Gliotem 250mg Capsule is used in the treatment of a specific type of cancer of the brain. It is used to treat brain tumors if they return or get worse after standard treatment. It may be also used to treat other conditions, as determined by the doctor.

Gliotem 250mg Capsule should be taken empty stomach and at same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, constipation, headache and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking it, tell your doctor if have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.

Uses of Gliotem Capsule

Brain tumor

Benefits of Gliotem Capsule

In Brain tumor

Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Gliotem 250mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Gliotem Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gliotem

Nausea
Vomiting
Constipation
Headache
Fatigue
Convulsion
Coordination disorder
Diarrhea
Dizziness
Fever
Hair loss
Hemiparesis (weakness on one side of the body)
Insomnia (difficulty in sleeping)
Loss of appetite
Memory loss
Rash
Viral infection
Weakness

How to use Gliotem Capsule

Take this medicine in the dose and duration as advised by your doctor. Gliotem 250mg Capsule is to be taken empty stomach.

How Gliotem Capsule works

Gliotem 250mg Capsule is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Gliotem 250mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Gliotem 250mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Gliotem 250mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Gliotem 250mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Gliotem 250mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Gliotem 250mg Capsule may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking Gliotem 250mg Capsule.

Liver

CAUTION

Gliotem 250mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Gliotem 250mg Capsule may be needed. Please consult your doctor.
Limited information is available on the use of Gliotem 250mg Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Gliotem Capsule?

If you miss a dose of Gliotem 250mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

Gliotem 250mg Capsule should be taken on an empty stomach.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.

Fact Box

Chemical Class

Dacarbazine Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

Interaction with drugs

Taking Gliotem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Molgramostim (Oral Route) Life-threatening

Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Temozolomide from 1 day before until 1 day after taking Molgramostim. ... More

Lenograstim (Oral Route) Life-threatening

Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot... More

Pegfilgrastim (Oral Route) Life-threatening

Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Temozolomide from 14 days before until 24 days after taking Pegfilgras... More

Sargramostim (Oral Route) Life-threatening

Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Temozolomide from 1 day before until 1 day after taking Sargramostim. ... More

Natalizumab (Oral Route) Life-threatening

Concomitant use may increase the risk of opportunistic infections. Do not consume Natalizumab with Temozolomide.

View all drug interactions

Patient concerns

any treatment of brain tumor w

Dr. Saurav Arora

Homeopathy

Dear sir in this case homeopathy can be given as add-on with conventional medicine. By doing so we can improve the longevity of patient, quality of life and decrease disease progression.

He is suffering of brain tumor gbm4 glioblastoma

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

User feedback

What are you using Gliotem Capsule for?

Brain tumor

100%

What were the side-effects while using Gliotem 250mg Capsule?

Nausea

100%

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

Marketer details

Name: Sun Pharmaceutical Industries Ltd

Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Country of origin: India

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