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MRP: Rs. 405.95 for 1 strip(s) (1 capsule each)
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Composition for GLIOTEM

Temozolomide(20 mg)

food interaction for GLIOTEM

alcohol interaction for GLIOTEM

pregnancy interaction for GLIOTEM

lactation interaction for GLIOTEM

food
alcohol
pregnancy
lactation
It is better to take Gliotem 20 mg capsule empty stomach (1 hour before food or 2 hours after food).
Interaction with alcohol is unknown. Please consult your doctor.
Gliotem 20 mg capsule is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Gliotem 20 mg capsule is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for GLIOTEM

Temozolomide(20 mg)

Uses

Gliotem 20 mg capsule is used in the treatment of brain tumor.

How it works

Gliotem 20 mg capsule is an antitumor drug and belongs to a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in the body.

Common side effects

Nausea, Pale colored skin, Altered vision, Memory impairment, Confusion, Constipation, Diarrhoea, Dizziness, Fainting, Fever, Hair loss, Headache, Insomnia, Loss of appetite, Balance disorder (loss of balance), Coordination impaired, Sore mouth, Sore throat, Vomiting, Weakness

SUBSTITUTES for GLIOTEM

9 Substitutes
Sorted By
RelevancePrice
  • GLIOZ 20MG CAPSULE
    (5 capsules in strip)
    Dr Reddy's Laboratories Ltd
    Rs. 404.13/capsule
    Capsule
    Rs. 2020.66
    same price
  • TEMODAL 20MG CAPSULE
    (5 capsules in strip)
    Fulford India Ltd
    Rs. 1585.71/capsule
    Capsule
    Rs. 7928.57
    pay 291% more per capsule
  • TEMOTRUST 20MG CAPSULE
    (5 capsules in strip)
    Panacea Biotec Ltd
    Rs. 394.09/capsule
    Capsule
    Rs. 1970.46
    save 3% more per capsule
  • NUBLAST 20MG CAPSULE
    (5 capsules in strip)
    Zydus Cadila
    Rs. 420/capsule
    Capsule
    Rs. 2100
    pay 3% more per capsule
  • GLISTROMA 20MG CAPSULE
    (5 capsules in strip)
    Alkem Laboratories Ltd
    Rs. 467.74/capsule
    Capsule
    Rs. 2338.68
    pay 15% more per capsule

Expert advice for GLIOTEM

  • Swallow full tablets on an empty stomach, one hour before your meal.
  • Avoid being near people who are sick or have infections. Consult your doctor if you develop symptoms of opportunistic infections (such as Pneumocystis jirovecii pneumonia) and reactivation of infections (such as hepatitis B virus) Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Be aware about your specific risk.
  • You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.
  • Your blood will be tested frequently during treatment to monitor the side effects of temozolomide on your blood cells as you may have a small risk of other changes in blood cells, including leukemia.
  • Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
  • Do not drink alcohol while taking temozolomide.
  • Do not drive or operate machinery while using temozolomide as it may make you tired or sleepy.
  • Both male and female patients should take effective contraceptive precautions during and after 6 months of treatment. Male patients should seek advice on conservation of sperm prior to treatment as temozolomide treatment may cause infertility.

Frequently asked questions for GLIOTEM

Temozolomide

Q.What is temozolomide used for/ what does temozolomide treat/ Is temozolomide chemotherapy/ is temozolomide cytotoxic/ is temozolomide a radiosensitizer?
Temozolomide is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer

Q.Is temozolomide effective/ does temozolomide work?
Temozolomide is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor

Q.How is temozolomide given/administered/ metabolized/ how long does temozolomide stay in the body?
Temozolomide is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours

Q.How does temozolomide cross the blood-brain barrier?
Temozolomide because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid

Q.Does temozolomide cause hair loss?
Hair loss is a side effect of using temozolomide. Always follow doctor's advice regarding its use

Q.Is temozolomide FDA approved?
Temozolomide is a FDA approved drug.

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Content on this page was last updated on 24 December, 2014, by Dr. Varun Gupta (MD Pharmacology)