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Genryzon Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 11 Mar 2026 | 01:03 AM (IST)
Genryzon Injection is a long-acting form of human growth hormone designed to help initiate growth-promoting effects similar to the body’s natural growth hormone. It is used to treat children with growth disturbances due to inadequate secretion of growth hormone (GH).
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General Information

Contains

Somatrogon (60mg)

Marketer

Pfizer Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Genryzon Injection image
Genryzon Injection image
Genryzon Injection image
Genryzon Injection image
Genryzon Injection image
Genryzon Injection image

Product introduction

Genryzon Injection is administered as a subcutaneous injection, usually once weekly, under the supervision of a doctor. Proper training and instructions should be received from a healthcare professional before self-administering this medicine. The dose is individualized by your doctor, based on body weight and clinical response.


The most common side effects associated with Genryzon Injection include injection site reactions (such as pain, redness, or swelling), headache, fatigue, and rash. If these effects worsen or become bothersome, the individual should inform their doctor. Measures may be available to minimize or manage these reactions.


Before starting this medicine, inform your doctor if you have diabetes mellitus, impaired glucose tolerance, thyroid disorders, or a history of malignancy. During treatment, your doctor may require regular monitoring of blood glucose levels, thyroid function tests, insulin-like growth factor-1 (IGF-1) levels, and clinical growth response to ensure safety and optimal therapeutic benefit.

Benefits of Genryzon Injection

Growth disturbances due to growth hormone deficiency
In children with growth disturbances caused by growth hormone deficiency, Genryzon Injection helps support more consistent physical growth. Genryzon Injection may increase the rate at which children grow compared with their growth before the treatment. Genryzon Injection helps the individual move towards normal growth patterns for their age by supporting growth hormone to reach a level that enables the body to use nutrients more effectively, supports healthy bone lengthening (linear growth), and increases the speed at which a child grows in height over time. However, it should be used only if prescribed by a doctor and should not be self-administered.

Side effects of Genryzon Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Genryzon
  • Injection site reactions (pain, swelling, redness)
  • Fever
  • Headache

How to use Genryzon Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Genryzon Injection works

Genryzon Injection is a long-lasting version of human growth hormone that helps people whose bodies do not produce enough of this important hormone naturally. When Genryzon Injection enters the bloodstream, it travels to tissues such as the liver, muscles, and bones and attaches to specific cells. It sends a signal inside the cells, prompting them to produce a substance called insulin-like growth factor-1 (IGF-1). IGF-1 is responsible for most of the actual growth effects in the body. What makes Genryzon Injection different from regular growth hormone treatments is that it is designed to stick around in your body much longer. Genryzon Injection helps your bones grow longer (especially important for children and teens), supports your body in building proteins (the building blocks your body needs), and helps regulate how your body grows and uses energy, essentially doing everything natural growth hormone does.

Quick tips

  • Take Genryzon Injection exactly as prescribed. Do not stop using it without your doctor’s advice.
  • Change injection spots every week. Use the thigh, belly, or arm; rotating prevents lumps from forming. Do not use the same spot twice.
  • Always check the liquid before injecting. It should look completely clear. Do not use it and get a replacement pen from the pharmacy if it is cloudy or has particles.
  • A small amount of the medicine may remain in the pen after all doses have been correctly given. This is normal. Patients should not try to use the remaining solution.
  • Use a brand-new needle each time, and do not reuse the needles. Old needles can cause infections. Fresh needles are always safer.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Genryzon Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Genryzon Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Genryzon Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Genryzon Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Genryzon Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Genryzon Injection in patients with liver disease.

Frequently asked questions

No. Genryzon Injection must not be used in children with active cancer or tumors, diabetic retinopathy, serious acute illness (such as after major surgery, trauma, or respiratory failure), or known allergy to its ingredients. The doctor will decide if this medicine is suitable for the individual.
The main difference is convenience; instead of giving your child a shot every single day, Somatrogon only needs to be injected once a week. Genryzon Injection is designed to release slowly and steadily throughout the week, so it keeps working between doses. The effects on growth are similar to daily injections.
The best injection sites are areas with a bit of fatty tissue under the skin: the abdomen (belly), the front and outer thighs, the back of the upper arms, and the buttocks. It is important to rotate the sites where you inject each week; do not use the same spot repeatedly. This rotation helps prevent skin irritation, lumps, or changes in how well the medication absorbs. Your healthcare provider can show you the best technique and specific spots to use.
Yes, Genryzon Injection can affect how your body handles sugar, and in some cases, it may raise blood sugar levels. This does not mean everyone will develop problems, but it is something to be aware of, especially if there is diabetes in your family. Your doctor will likely check your child's blood sugar levels periodically during treatment. Watch for signs like increased thirst, frequent urination, or unusual tiredness, and report these to your doctor.
Before you first use the pen, keep it in the refrigerator (not the freezer). Once you have started using a pen, you can keep it in the fridge or at room temperature (25°C) for up to 28 days. Always keep the cap on when you are not using it. Check the manufacturer's instructions that come with your specific pen, as storage guidelines can vary slightly.
No. Discontinuing the medication without consulting your doctor may compromise treatment goals. Always consult your doctor before making changes.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

HORMONES
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: Belgium
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