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MRP: Rs. 6131 for 1 vial(s) (1 injection each)
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Composition for GEMITA

Gemcitabine(1000 mg),Mannitol(62.5 mg)

food interaction for GEMITA

alcohol interaction for GEMITA

pregnancy interaction for GEMITA

lactation interaction for GEMITA

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Gemita 1000mg/62.5mg injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Gemita 1000mg/62.5mg injection is probably unsafe to use during breastfeeding. Please consult your doctor.


Gemcitabine(1000 mg)


Gemcitabine is used in combination with other drugs for the treatment of local or advanced cancers like non-small cell lung cancer, epithelial ovarian cancer, bladder cancer, adenocarcinoma of the pancreas. It is also used for treating recurrent breast cancer that cannot be treated with surgery.

How it works

Gemcitabine belongs to a class of medication called anti-metabolites. It is cytotoxic in nature. They kill rapidly dividing cells (e.g. cancer cells) thus slowing down the spread of cancer in the body.

Common side effects

Decreased urination, Constipation, Diarrhoea, Fever, Hair loss, Headache, Influenza like symptoms, Loss of appetite, Mouth ulcer, Nausea, Sore throat, Tarry stools, Urine discolouration, Vomiting
Mannitol(62.5 mg)


Mannitol is used to prevent or treat excess body water in certain kidney conditions, such as oliguric phase (production of abnormally small amounts of urine) of acute renal failure and for reducing swelling of the brain, or reducing pressure in the eye.

How it works

Mannitol belongs to a class of drugs called osmotic diuretics. Mannitol works by increasing the amount of fluid excreted by the kidneys and helps the body to decrease pressure in the brain and eyes.

Common side effects

Nausea, Pulmonary edema, Acidosis, Anaphylactic reaction, Chest pain, Chills, Convulsion, Dizziness, Electrolyte imbalance, Fever, Headache, Increased blood pressure, Inability to empty the urinary bladder, Inflammation of vein due to blood clot in the blood vessels, Vomiting


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Expert advice for GEMITA

  • Not recommended in children or adolescents below 18 years of age.
  • Inform your doctor if you have history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression).
  • Inform your doctor if you have breathing problems or feel weak and pale as this could be a sign of kidney dysfunction; unexplained new or worsening dyspnea or evidence of severe pulmonary toxicity.
  • Take precautions if you are on a controlled sodium diet, as this medicine contains some amount of sodium.
  • You should undergo blood count, heart/kidney/liver function tests before therapy.
  • Do not take live or attenuated vaccines during therapy and avoid contact with persons who receive them.
  • Alcohol is an ingredient of this infusion. If you are suffering from alcoholism or epilepsy, you may have serious side effects. Other medication taken at this time may have altered effects. 
  • Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies. 
  • They should use two effective methods of contraception while on this therapy and 6 months after it.
  • Men who are going to use this therapy should not father a child while on this therapy and 6 months after it. They should also seek guidance and counselling on sperm conservation before taking this therapy.
  • Do not drive or use machinery after taking this drug as it may cause sleepiness which may worsen with alcohol use.

Frequently asked questions for GEMITA


 Q. Is gemcitabine a vesicant/ anthracycline/ prodrug?
Gemcitabine is not a vesicant/ anthracycline/ prodrug.
Q. Does gemcitabine cause hair loss or abdominal pain?
Yes, gemcitabine has hair loss and abdominal pain as side effects. Please consult your doctor immediately if you experience such side effects.
Q. Is gemcitabine a cytotoxic or chemotherapy agent?
Yes, gemcitabine is a cytotoxic chemotherapy agent.
Q. Does gemcitabine work in pancreatic cancer?
Yes, gemcitabine is used to treat pancreatic cancer.


Q. Is mannitol a sugar?
Mannitol is a polyol (sugar alcohol).

Q. Is mannitol salt agar selective?
Yes, mannitol salt agar is a selective, differential and Indicator medium.


Content on this page was last updated on 07 July, 2014, by Dr. Varun Gupta (MD Pharmacology)