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GEMcal -Kit is a combination medicine used in the treatment of osteoporosis. It prevents bone loss and makes the bones stronger. This way it helps prevent bone fractures.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Apr 2026 | 04:05 PM (IST)
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GEMcal -Kit image
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Product introduction

GEMcal -Kit is best taken on an empty stomach. You should take it regularly at a fixed time each day. Taking it at the same time every day will help you remember to take it. It may take several days to get the full benefit of this drug. Do not stop taking the medicine until your doctor tells you it is right to stop. This medicine may only be part of a treatment program that may also include changes to your diet and taking other medicines and vitamin supplements.


The most common side effects of GEMcal -Kit include headache, back pain, musculoskeletal (bone, muscle, or joint) pain, indigestion, heartburn, and diarrhea. These are generally mild and usually resolve on their own. If they do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.


Before using GEMcal -Kit, let your doctor know if you have any medical conditions or disorders. To make sure the medicine is safe for you, let your doctor know all the other medicines you are taking. You may need frequent medical tests to check your kidney function and mineral levels while on treatment with this medicine. You should avoid consuming large amounts of alcohol, as it can cause bone loss. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of GEMcal Tablet

Benefits of GEMcal Tablet

Treatment of Osteoporosis
Osteoporosis is a common condition that causes bones to become fragile and brittle so that they break (fracture) more easily. Fractures may be painful and restrict a person’s ability to carry out their normal daily tasks. GEMcal -Kit reduces the risk of a fracture occurring in osteoporosis. It also helps in the growth and development of bones as well as maintaining strong bones. Along with medicines, eat a balanced diet rich in calcium and vitamin D, like dairy products, green leafy vegetables, etc.

Side effects of GEMcal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of GEMcal
  • Headache
  • Increased calcium level in blood
  • Abdominal pain
  • Nausea
  • Rash
  • Urinary tract infection

How to use GEMcal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. GEMcal -Kit is to be taken on an empty stomach.

How GEMcal Tablet works

GEMcal -Kit is a combination of four medicines: calcitriol, calcium carbonate, zinc, and risedronate, which treat osteoporosis. Calcitriol is a form of vitamin D that helps your body effectively absorb calcium carbonate and supports the muscles needed to avoid falls. Calcium carbonate and zinc are minerals that help build and maintain bones. Risedronate is a bisphosphonate that works by suppressing the activity of osteoclasts, cells that destroy bone. This strengthens the bone and minimizes the risk of fractures.

Quick tips

  • Drink plenty of water while taking this medicine.
  • Along with taking GEMcal -Kit, maintain a healthy lifestyle, take a balanced diet, exercise (regular weight-bearing exercise) with your doctor's advice, and take proper measures to reduce the risk of falls.
  • Let your doctor know if you’re taking an iron supplement, as the absorption rate might be affected.
  • Inform your doctor if you have kidney problems or if you have ever had kidney stones.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with GEMcal -Kit. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of GEMcal -Kit during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
GEMcal -Kit may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
GEMcal -Kit may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
GEMcal -Kit should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
No dose adjustment is recommended in patients with mild to moderate kidney disease. However, use of GEMcal -Kit is not advised in severe kidney disease patients.
Liver

Liver

CAUTION
GEMcal -Kit should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

You should take GEMcal -Kit first thing in the morning on an empty stomach with a full glass of water (not juice/coffee).
Individuals should avoid using GEMcal -Kit if they are allergic to any of its ingredients. It should also be avoided in cases of high blood calcium levels (hypercalcemia), severely reduced kidney function, or bone softening not caused by vitamin D deficiency. Additionally, people with esophageal problems (such as difficulty swallowing or a very narrow food pipe) or those unable to stand or sit upright for at least 30 minutes should not use GEMcal -Kit.
While taking GEMcal -Kit, avoid lying down for at least 30 minutes afterward, as it may irritate your food pipe. Do not take calcium, antacids, or iron supplements within 2 hours of this medicine, as they can reduce its absorption. Also, avoid taking it with milk or dairy products, as they may interfere with how well it works.
During GEMcal -Kit treatment, contact your doctor immediately if you experience chest pain or difficulty swallowing, as these may be signs of esophageal damage. Seek help if you notice severe bone, joint, or muscle pain, jaw pain or swelling (which could indicate a rare condition called osteonecrosis of the jaw, where the jawbone doesn’t heal properly), eye pain or vision changes, or worsening of asthma (if you have or had asthma).
The exact time GEMcal -Kit takes to show its benefits is not known. However, you may expect improvement in bone density in a few months of regular use. Your doctor may do scans to observe how you are doing on the GEMcal -Kit treatment.
Avoid self-administering GEMcal -Kit if you have a kidney or any other disease. GEMcal -Kit requires dosage adjustment in kidney issues. Your doctor may closely monitor serum calcium/creatinine levels.
You should inform your dentist if you are taking GEMcal -Kit. GEMcal -Kit may need to be paused if you are having tooth extractions, getting dental implants, or experiencing jaw infections/pain.

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User feedback

Once A Day
100%
Others
83%
Nutritional deficiencies
17%
Poor
48%
Excellent
29%
Average
24%
No Side Effect
56%
Headache
11%
Back pain
11%
Heartburn
11%
Indigestion
11%
With food
62%
Empty stomach
38%
Expensive
38%
Average
33%
Not Expensive
29%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver GEMcal -Kit. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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