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Composition for GCOM

Gatifloxacin Topical(0.3% w/v),Ketorolac(4% w/v)

food interaction for GCOM

alcohol interaction for GCOM

pregnancy interaction for GCOM

lactation interaction for GCOM

There is no data available. Please consult doctor before consuming the drug.
Taking Ketorolac with alcohol increases the risk of stomach bleeding.
Gcom 0.3%/4% eye drops may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Gatifloxacin Topical(0.3% w/v)


Gatifloxacin topical is used as a local treatment for bacterial eye infection (conjunctivitis) and ear infections in adults and children older than 1 year of age.

How it works

Gatifloxacin belongs to the class of medications called as fluoroquinolone antibiotics. It inhibits protein synthesis in the susceptible bacteria, thereby killing the bacteria.

Common side effects

Altered taste, Blurred vision, Eye irritation, Eye redness, Teary eyes, Eyelid swelling, Eye itching, Eye discharge, Eye pain
Ketorolac(4% w/v)


Ketorlac is used orally and as injectable form for short term (3-5 days) relief of moderately severe pain. It is also used as eye drops to prevent and treat pain and swelling in the eye after eye surgery.

How it works

Ketorolac belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the effect of enzyme called cyclooxygenase resulting in decreased production of prostaglandins (a chemical associated with pain) thereby easing pain, swelling and inflammation.

Common side effects

Constipation, Diarrhoea, Dizziness, Drowsiness, Flatulence, Headache, Increased sweating, Sore lip, Sore mouth


No substitutes found

Expert advice for GCOM

  • Avoid contact lenses if you have bacterial conjunctivitis or you are applying eye drops. 
  • Inform your doctor about your existing medical conditions, allergies, and all medicines that you use.
  • Do not drive or operate machinery as you may have blurred vision after using gatifloxacin topical.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • It should not take if patient is allergic to gatifloxacin or any of its ingredients. 

Frequently asked questions for GCOM

Gatifloxacin Topical

Q. Does gatifloxacin topical contain sulfa?
Gatifloxacin topical does not contain sulfa. It is a fluoroquinolone antibiotic.
Q. Is gatifloxacin topical the same as Zymaxid?
Zymaxid is the brand name for gatifloxacin eye solution.
Q. Is gatifloxacin topical the same as ofloxacin?
Both gatifloxacin and ofloxacin are fluoroquinolone antibiotics and have the same mechanism of killing bacteria. Ofloxacin topical is used to treat eye and ear infections, whereas gatifloxacin is used in the form of eye/ear drops for the treatment of eye and ear infections only. They are also different with respect to the side-effects they cause.
Q. Is gatifloxacin topical banned in India?
Gatifloxacin is banned in India for oral/injectable use in humans, however its use as eye/ear drops is not banned.


Q. Is ketorolac same as tramadol, aspirin, codeine, acetaminophen?
No. Ketorolac is non-steroidal anti-inflammatory drug (NSAID) while tramadol, codeine are opioid (derived from opium) pain killers. Aspirin and acetaminophen are NSAIDs different than ketorolac.

Q. What is Toradol?
 Toradol is proprietary (brand) name of ketorolac trometamine.
Q. Is ketorolac stronger than hydrocodone?
No. Opioid agents (hydrocodone) are generally stronger pain relievers than non-steroidal anti-inflammatory drug like ketorolac.
Q. Is ketorolac a muscle relaxer, blood thinner, or sulfa drug?
Ketorolac is a non-steroidal anti-inflammatory drug and can be used to treat mild pain and inflammation. It is however extensively prescribed to treat pain occurring after eye surgery and administered directly into the eyes. It is not a muscle relaxant, blood thinner or sulfa drug.
Q. Is ketorolac addictive or controlled substance?
No. Ketorolac is not addictive or controlled substance however it belongs to schedule H drug category and can be obtained only on production of valid prescription.
Q. Can I take ketorolac with Vicodin, Aleve, ibuprofen, oxycodone, tramadol, hydrocodone, cyclobenzaprine, Tylenol or naproxen?
Tylenol is the brand name of paracetamol (acetaminophen). Aleve is the brand name of naproxen. Vicodin contains paracetamol and hydrocodone. It is not advisable to take two or more non-steroidal anti-inflammatory drugs (NSAIDs) together as it increases the risk of adverse effects. Therefore Tylenol, Aleve, ibuprofen shouldn’t be taken with ketorolac. Cyclobenzaprine is a muscle relaxant and may be given if ketorolac is used as tablet or injection to treat pain in muscles and joints.
Q. Does ketorolac cause drowsiness or urinary retention?
Yes. NSAIDs may cause sleepiness or fluid retention in some patients but small doses given in eyes are unlikely to cause such effect with ketorolac.
Q. Can I take ketorolac for a headache, cramps, toothache or back pain?
Ketorolac eye drops are generally used in the treatment of mild to moderate pain after the surgery. In order to relieve headache, cramps, toothache or back pain, tablet or injection may be required.
Q. Does ketorolac expire?
Like all drugs, ketorolac has an expiry date, which will be printed on the eye drop bottle. Do not use ketorolac eye drops beyond expiry date.


Content on this page was last updated on 20 March, 2014, by Dr. Varun Gupta (MD Pharmacology)