


Gabaprime Plus Gel
Gabapentin (6% w/w)+ Lidocaine (5% w/w)+ Baclofen (2% w/w)
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Gabaprime Plus Gel is a prescription medicine used for the treatment of neuropathic pain. It works by first cooling and then warming up the skin. Thus, it calms the damaged or overactive nerves by acting on the brain, thereby decreasing the sensation of pain.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 02 Aug 2026 | 01:04 AM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 02 Aug 2026 | 01:04 AM (IST)
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Gabaprime Plus Gel
tube of 30 gm Gel
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Same composition
Gabipenta Gel
tube of 30 gm Gel
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General Information
The content is shown in English



Product introduction
Gabaprime Plus Gel is for external use only. You should use this in the dose and duration advised by your doctor. Clean and dry the affected area before applying this medicine to the skin. You should always wash your hands after applying it unless hands are the affected area.
There are no major side effects associated with this medicine, but it can cause some application site burning, irritation, itching or redness. However, these side effects are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
Uses of Gabaprime Gel
Benefits of Gabaprime Gel
Neuropathic pain
Gabaprime Plus Gel is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life.
Gabaprime Plus Gel is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life.
Side effects of Gabaprime Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gabaprime
- Application site reactions (burning, irritation, itching and redness)
How to use Gabaprime Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
How Gabaprime Gel works
Gabaprime Plus Gel is composed of three medicines gabapentin, lidocaine and baclofen. Gabapentin works by binding to calcium channels in nerve cells, which reduces the release of pain signals and calms overactive nerves involved in neuropathic pain. Lidocaine is a local anesthetic that blocks sodium channels on nerve endings, preventing the transmission of pain signals from the affected area to the brain. Baclofen acts on GABA receptors in the spinal cord to reduce nerve excitability and relieve muscle spasms that may accompany nerve pain. Together, these three components target different mechanisms of pain, offering effective relief from the burning, tingling, and shooting sensations commonly seen in neuropathic conditions.
All substitutes for Gabaprime Plus Gel
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Gabaprime Plus Gel is used to treat certain types of long-lasting pain caused by damage to nerves.
- Avoid contact with the eyes, mouth, nose and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Along with taking Gabaprime Plus Gel, your doctor might advise you to undergo physiotherapy to get relief from pain.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Gabaprime Plus Gel during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Gabaprime Plus Gel may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established

Frequently asked questions
Gabaprime Plus Gel is used to treat neuropathic pain caused by nerve damage. A doctor may also prescribe this medicine to manage pain associated with joints or injury.
Yes, Gabaprime Plus Gel can be used for local joint and muscle pain due to nerve problems, muscle tightness, or chronic pain conditions such as back pain, arthritis, etc.
Mild irritation may occur after applying Gabaprime Plus Gel. However, if it persists or gets worse, stop using the medicine and contact your doctor.
Yes, Gabaprime Plus Gel is often prescribed for diabetic neuropathy and nerve pain after some surgeries to provide local relief.
If you see no benefit, or your pain or skin symptoms get worse, stop using Gabaprime Plus Gel and see your doctor for further advice.
You should leave a 30-minute gap before or after using other skin products and Gabaprime Plus Gel to avoid reactions or reduce effectiveness.
Do not use dressings or bandages after applying Gabaprime Plus Gel unless your doctor specifically tells you. This may increase absorption and potential side effects.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References
- Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
- White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
- White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 451-468.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Starus Pharmaceuticals
Address: STARUS PHARMACEUTICALS PRIVATE LIMITED, 1st FLOOR, MOPARTHY TOWERS, LANE BESIDE KARACHI BAKERY, ROAD NO:1, BANJARA HILLS, HYDERABAD-500034, INDIA
Address: STARUS PHARMACEUTICALS PRIVATE LIMITED, 1st FLOOR, MOPARTHY TOWERS, LANE BESIDE KARACHI BAKERY, ROAD NO:1, BANJARA HILLS, HYDERABAD-500034, INDIA
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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