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Epsipan L Tablet is a medicine used to treat gastroesophageal reflux disease (acid reflux) by relieving the symptoms of acidity, such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Dec 2025 | 12:55 PM (IST)
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Epsipan L Tablet image
Epsipan L Tablet image

Product introduction

Epsipan L Tablet can be taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects are stomach pain, vomiting, diarrhea, headache, fever, nausea, rash, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine, as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food, or chocolate can help you get better results.


Before you start taking this medicine, it is important to inform your doctor if you are suffering from kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Benefits of Epsipan L Tablet

Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your oesophagus and mouth. Epsipan L Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Epsipan L Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epsipan L
  • Stomach pain
  • Vomiting
  • Diarrhea
  • Nausea
  • Headache
  • Flatulence
  • Dizziness
  • Joint pain

How to use Epsipan L Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epsipan L Tablet may be taken with or without food.

How Epsipan L Tablet works

Levosulpiride is a prokinetic that works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of the stomach and intestines and prevents reflux (acid going up to the food pipe). Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and ulcers.

All substitutes for Epsipan L Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Epsipan L Tablet can be taken with or without food. Take it preferably 30 minutes before food.
  • Inform your doctor if you get watery diarrhea or stomach pain that does not go away.
  • Do not consume alcohol while taking Epsipan L Tablet, as it can increase the risk of stomach damage.
  • Long-term use of Epsipan L Tablet may cause weak or broken bones. Take an adequate intake of dietary calcium and vitamin D or their supplements. Do not take Epsipan L Tablet for longer than prescribed.
  • Epsipan L Tablet is prescribed to give relief from acidity and its associated symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Epsipan L Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Epsipan L Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Epsipan L Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Epsipan L Tablet may cause side effects that could affect your ability to drive.
Epsipan L Tablet may cause drowsiness, dizziness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Kidney

Kidney

CAUTION
Epsipan L Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Epsipan L Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Epsipan L Tablet may be taken with or without food. Take it exactly as directed by your doctor for the best results.
The use of Epsipan L Tablet should be avoided in patients with known allergies to any of the components or excipients of this medicine.
Yes, the use of Epsipan L Tablet can cause dizziness (feeling faint, weak, unsteady, or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume your activities once you feel better.
Several studies in adults suggest that Epsipan L Tablet may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine. The risk of fracture was higher in patients who received high doses. High doses can mean multiple daily doses, and long-term therapy (a year or longer).

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aprica Pharmaceuticals Pvt Ltd
Address: A/4 4th Floor, Safal Profitaire,Corporate Road,Nr Prahladnagar Garden, Prahladnagar,Ahmedabad- 380015, Gujarat, India.

Vendor Details

Country of origin: India
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