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Epriplus Tablet SR is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 21 Sep 2025 | 05:35 PM (IST)
₹206 MRP ₹233.4412% off 
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General Information

Contains

Eperisone (150mg)+ Aceclofenac (200mg)

Marketer

Skycee Healthcare

Storage

Store below 25°C
The content is shown in English
Epriplus Tablet SR image
Epriplus Tablet SR image
Epriplus Tablet SR image

Product introduction

Epriplus Tablet SR should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.


Some of the common side effects of this medicine include nausea, vomiting, stomach pain, loss of appetite, diarrhea, and dizziness. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.


The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of Epriplus Tablet SR

  • Pain due to muscle spasm

Benefits of Epriplus Tablet SR

Pain due to muscle spasm
Epriplus Tablet SR treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly. It is advisable to continue taking Epriplus Tablet SR until your doctor advises you to stop.

Side effects of Epriplus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epriplus
  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain/epigastric pain
  • Loss of appetite
  • Diarrhea
  • Dizziness
  • Weakness
  • Sleepiness

How to use Epriplus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epriplus Tablet SR is to be taken with food.

How Epriplus Tablet SR works

Epriplus Tablet SR is a combination of two medicines: Eperisone and Aceclofenac, which relieve pain and relax the muscles. Eperisone is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

All substitutes for Epriplus Tablet SR

For information purposes only. Consult a doctor before taking any medicine.

Acemyoset Tablet SR

by Sparsh Remedies Pvt Ltd
₹20.7/tablet sr
same price
<h3 class=bodySemiBold>Acemyoset Tablet SR</h3>

Meuzosone-AC Tablet SR

by Vanprom Lifesciences Pvt Ltd
₹21.6/tablet sr
5% costlier
<h3 class=bodySemiBold>Meuzosone-AC Tablet SR</h3>

Quick tips

  • Epriplus Tablet SR is usually used along with rest and physical therapy.
  • Take it with food to avoid an upset stomach.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Epriplus Tablet SR, as it may cause excessive drowsiness.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Epriplus Tablet SR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Epriplus Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Epriplus Tablet SR during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Epriplus Tablet SR may cause side effects which could affect your ability to drive.
Kidney

Kidney

CAUTION
Epriplus Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Epriplus Tablet SR may be needed. Please consult your doctor.
Use of Epriplus Tablet SR is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Epriplus Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Epriplus Tablet SR may be needed. Please consult your doctor.
Use of Epriplus Tablet SR is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while the patient is taking this medicine.

Frequently asked questions

Epriplus Tablet SR is used to relieve muscle pain and stiffness, especially in conditions like back pain, neck pain, arthritis, or muscle spasms.
You should avoid taking Epriplus Tablet SR if you are allergic to eperisone, aceclofenac, or other NSAIDs such as ibuprofen. Do not take this medicine if you have stomach ulcers, bleeding, or other digestive problems. It should also be avoided if you have liver or kidney disease, heart failure, or a history of heart attacks. Additionally, it is not recommended during the later stages of pregnancy.
You should stop taking Epriplus Tablet SR and contact your doctor immediately if you experience serious side effects. These may include severe stomach pain, vomiting blood, or black stools (which could indicate a bleeding ulcer), yellowing of the skin or eyes (a possible sign of liver problems), and chest pain or shortness of breath (which may signal an asthma attack). You should also seek help if you notice allergic reactions such as a rash, itching, or swelling of the face or lips.
The exact time Epriplus Tablet SR takes to work is not known. However, you may start noticing a reduction in pain in a few hours.
Yes, Epriplus Tablet SR may cause sleepiness and light-headedness. You should avoid indulging in activities requiring alertness until the symptoms subside.
Yes, gastrointestinal issues such as stomach pain, diarrhea, or constipation are some common side effects associated with Epriplus Tablet SR. Consult your doctor if these side effects disturb your daily routine. Additionally, monitor and report immediately if any signs of blood in the stool are observed.
The safety and efficacy of Epriplus Tablet SR in children have not been evaluated. It is always a safer and better choice to consult a doctor before giving any medicine to the child.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Eperisone. Bunkyo-ku, Tokyo: Eisai Co., Ltd.; 2009. [Accessed 29 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Skycee Healthcare
Address: GANDHI NAGAR, ASSAM

Vendor Details

Country of origin: India

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