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Epocrez 4K Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by medicines to treat HIV.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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0.1 ml Injection
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General Information

The content is shown in English
Epocrez 4K Injection image
Epocrez 4K Injection image

Product introduction

Epocrez 4K Injection is given by injection either under the skin or into a vein, which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Epocrez 4K Injection needs to be stored in a fridge but used at room temperature.


The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness, and aches and pains. These side effects are most common at the start of treatment, but if they persist, your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes, this medicine can cause serious blood clots that need urgent medical attention.


Before using Epocrez 4K Injection, you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (a disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Benefits of Epocrez Injection

Treatment of Anemia due to cancer chemotherapy
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epocrez 4K Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.
Treatment of Anemia due to chronic kidney disease
Epocrez 4K Injection is a man-made protein that helps your bone marrow to produce more red blood cells. It is used to treat anemia which is caused by kidney disease in adults and children who are on dialysis. Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. This medicine helps reduce weakness and tiredness that you may be experiencing due to anemia. The injection is usually given by a doctor after a dialysis treatment.

Side effects of Epocrez Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epocrez
  • Muscle spasm
  • Dizziness
  • Vascular occlusion
  • Injection site irritation
  • Stomatitis (Inflammation of the mouth)
  • Weight loss
  • Decreased white blood cell count (lymphocytes)
  • Increased glucose level in blood
  • Blood clot in the blood vessels
  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Rash
  • Joint pain
  • Headache
  • Insomnia (difficulty in sleeping)
  • Chills

How to use Epocrez Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Epocrez Injection works

Epocrez 4K Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Quick tips

  • Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, and electrolytes such as potassium in your blood.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure, such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
  • Stop taking Epocrez 4K Injection and inform your doctor if you develop shortness of breath or a skin rash.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Epocrez 4K Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Epocrez 4K Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Epocrez 4K Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Epocrez 4K Injection may cause side effects that could affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Epocrez 4K Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver

Liver

CAUTION
Epocrez 4K Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Tell the doctor or nurse immediately if you think too much Epocrez 4K Injection has been injected.
Epocrez 4K Injection should not be used if the solution is cloudy, or if you can see particles floating in it, or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.
Yes, Epocrez 4K Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Epocrez 4K Injection and side effects seen in children are similar to adults.
Yes, Epocrez 4K Injection can affect blood pressure. During initial therapy with Epocrez 4K Injection, blood pressure should be monitored, and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Epocrez 4K Injection if the blood pressure remains uncontrolled.
In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8℃. If you are using this medicine at home, the pre-filled syringe must be stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature before using it. This usually takes between 15 and 30 minutes. Epocrez 4K Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Erythropoiesis-Stimulating Agents (ESAs)
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100% genuine products
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cryzer Formulation
Address: krishna vatika sudamapuri, near gaur city, nh 24, noida phase-2, ghaziabad, 201001

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Epocrez 4K Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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