Epofit 4000IU Injection
Prescription Required
Product introduction
Epofit 4000IU Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV.
Epofit 4000IU Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Epofit 4000IU Injection needs to be stored in a fridge but used at room temperature.
The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention.
Before using Epofit 4000IU Injection you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
Uses of Epofit Injection
Benefits of Epofit Injection
In Treatment of Anemia due to cancer chemotherapy
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epofit 4000IU Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.
In Treatment of Anemia due to chronic kidney disease
Epofit 4000IU Injection is a man-made protein that helps your bone marrow to produce more red blood cells. It is used to treat anemia which is caused by kidney disease in adults and children who are on dialysis. Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. This medicine helps reduce weakness and tiredness that you may be experiencing due to anemia. The injection is usually given by a doctor after a dialysis treatment.
Side effects of Epofit Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epofit
- High blood pressure
- Nausea
- Vomiting
- Fever
- Rash
- Joint pain
- Headache
- Insomnia (difficulty in sleeping)
- Chills
- Cough
- Bone pain
- Muscle spasm
- Dizziness
- Vascular occlusion
- Injection site irritation
- Stomatitis (Inflammation of the mouth)
- Weight loss
- Decreased white blood cell count (lymphocytes)
- Increased glucose level in blood
- Blood clot in the blood vessels
How to use Epofit Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Epofit Injection works
Epofit 4000IU Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Epofit 4000IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Epofit 4000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Epofit 4000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Epofit 4000IU Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Epofit 4000IU Injection is safe to use in patients with kidney disease. No dose adjustment of Epofit 4000IU Injection is recommended.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver
CAUTION
Epofit 4000IU Injection should be used with caution in patients with liver disease. Dose adjustment of Epofit 4000IU Injection may be needed. Please consult your doctor.
What if you forget to take Epofit Injection?
If you miss a dose of Epofit 4000IU Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Epofit 4000IU Injection
₹1918/Injection
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Quick tips
- Epofit 4000IU Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
- It is given as a single injection under your skin.
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
- Stop taking Epofit 4000IU Injection and inform your doctor if you develop shortness of breath or skin rash.
Fact Box
Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Erythropoiesis-stimulating agent (ESA)
Patient concerns
User feedback
Patients taking Epofit 4000IU Injection
Twice A Week
60%
Once A Week
40%
What are you using Epofit Injection for?
Anemia due to*
75%
Others
25%
*Anemia due to chronic kidney disease
How much was the improvement?
Average
44%
Excellent
33%
Poor
22%
What were the side-effects while using Epofit 4000IU Injection?
High blood pr*
50%
No Side Effec*
25%
Rash
25%
*High blood pressure, No Side Effect
How do you take Epofit Injection?
With food
50%
With or witho*
50%
*With or without food
Please rate Epofit 4000IU Injection on price
Average
50%
Expensive
50%
FAQs
How should Epofit 4000IU Injection be stored?
In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8 ℃. If you are using this medicine at home, it is important that the pre-filled syringe is stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Epofit 4000IU Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.
What to do if you use too much Epofit 4000IU Injection?
Tell the doctor or nurse immediately if you think too much Epofit 4000IU Injection has been injected.
When should Epofit 4000IU Injection not be used?
Epofit 4000IU Injection should not be used if the solution is clouded or you can see particles floating in it or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.
Can Epofit 4000IU Injection be used in children?
Yes, Epofit 4000IU Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Epofit 4000IU Injection and side effects seen in children are similar to adults.
Can Epofit 4000IU Injection affect blood pressure?
Yes, Epofit 4000IU Injection can affect blood pressure. During initial therapy with Epofit 4000IU Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Epofit 4000IU Injection if the blood pressure remains uncontrolled.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- ScienceDirect. Recombinant Human Erythropoietin Alfa/Epoetin Alfa. [Accessed 07 Apr. 2019] (online) Available from:
- Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Leiden, Netherlands: Janssen Biologics B.V; [revised Oct. 2018]. [Accessed 07 Apr. 2019] (online) Available from:
- Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Amgen Inc; 1989 [revised Dec. 2013]. [Accessed 07 Apr. 2019] (online) Available from:
- Epoetin alfa [Prescribing Information]. Horsham, Pennsylvania: Janssen Products, LP; 2017. [Accessed 28 Mar. 2023] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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1.0 ml in 1 prefilled syringe
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