Epithra 50 Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 30 Jan 2026 | 03:40 PM (IST)

Epithra 50 Injection is used in the treatment of various types of cancers of blood, breast, stomach, lung, ovaries and soft tissues. It also helps to prevent the recurrence of bladder cancer after surgery.

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1 Injection

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Cold stored

Stored between 2-8°C

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General Information

Contains

Epirubicin (50mg)

Marketer

Glenmark Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. It can be used alone, or sometimes given together with certain other medicines as part of combination chemotherapy. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include nausea, low blood platelets, hair loss, absence of menstrual periods, fever and rash. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have liver disease, or have heart problem. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding.

Uses of Epithra Injection

Cancer

Benefits of Epithra Injection

Cancer
Epithra 50 Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Epithra 50 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Epithra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epithra

Low blood platelets
Nausea
Hair loss
Absence of menstrual periods
Fever
Anemia (low number of red blood cells)
Diarrhea
Weight loss
Decreased white blood cell count (neutrophils)
Hot flashes
Gastrointestinal inflammation
Rash
Low energy
Eye disorder

How to use Epithra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Epithra Injection works

Epithra 50 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the breast cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of breast cancer cells and eventually kills them.

All substitutes for Epithra 50 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Epithra 50 Injection is used alone or in combination with other medicines for the treatment of various types of cancers.
It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Epithra 50 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Epithra 50 Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Epithra 50 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Epithra 50 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Epithra 50 Injection may cause episodes of nausea and vomiting, which can temporarily lead to an impairment of the ability to drive.

Kidney

SAFE IF PRESCRIBED

Epithra 50 Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Lower doses may be considered in patients with serum creatinine > 5 mg/dL.

Liver

CAUTION

Epithra 50 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Epithra 50 Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Epithra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening