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Epalrest-M Tablet is a medicine used in the treatment of diabetic nerve disease. It protect the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
₹135 MRP ₹146.258% off 
 
 
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Epalrest-M Tablet image
Epalrest-M Tablet image

Product introduction

Epalrest-M Tablet may be taken with or without food, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

The most common side effects of this medicine include nausea, vomiting, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.

Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.

Uses of Epalrest-M Tablet

Benefits of Epalrest-M Tablet

Diabetic nerve pain
Epalrest-M Tablet is a medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and also improves nerve conduction. Taking Epalrest-M Tablet regularly will improve your physical and social functioning and overall quality of life.

Side effects of Epalrest-M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epalrest-M
  • Nausea
  • Vomiting
  • Increased liver enzymes

How to use Epalrest-M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalrest-M Tablet may be taken with or without food.

How Epalrest-M Tablet works

Epalrest-M Tablet is a combination of two medicines:.

Quick tips

  • Take it only as per the dose and duration prescribed by your doctor. 
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Inform your doctor if you have:
    • Cut or sore on your feet that is infectious or not healing
    • Burning or tingling sensation in arm or feet that hamper your routine activities
    • Trouble in digestion, urination, or sexual functioning
    • Dizziness
  • To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
  • Monitor your blood sugar level regularly.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Epalrest-M Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Epalrest-M Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Epalrest-M Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Epalrest-M Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Epalrest-M Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Epalrest-M Tablet in patients with liver disease.

Frequently asked questions

Epalrest-M Tablet is mainly used to treat diabetic neuropathy, a nerve problem caused by diabetes that can lead to pain, tingling, numbness, or weakness—especially in the legs and feet.
Individuals should not take Epalrest-M Tablet if they are allergic to vitamin B12 or any ingredient in the medicine, have a rare inherited eye condition called Leber's hereditary optic neuropathy (which causes vision loss), or toxic optic neuropathy related to tobacco use. Also, do not use it if you have diabetic ketoacidosis (a serious diabetes complication).
Although they are rare, serious side effects of Epalrest-M Tablet include skin rash, itching, nausea, stomach pain, headaches, dizziness, fatigue, severe confusion, extreme tiredness, or allergic reactions (swelling, trouble breathing). Seek medical help immediately if you experience any of these symptoms.
Symptoms of Epalrest-M Tablet overdose may include extreme fatigue, confusion, and significant gastrointestinal discomfort. If you suspect an overdose, seek emergency medical attention immediately.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Related lab tests

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Johnlee Pharmaceuticals Pvt Ltd
Address: 42/44, Babu Genu Road, Shop No. 06, 2nd Floor, Om Shanti Co-op Housing Society, Kalbadevi Road, Mumbai-400002. (India)

Vendor Details

Country of origin: India
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