MRP:Rs. 175.75 for 1 strip(s) (10 tablet each)


Trypsin(48 mg)


Trypsin is used to treat osteoarthritis, ulcers, wound cleansing and healing and to improve digestion.

How it works

Trypsin is an enzyme, which breaks down proteins into smaller fragments, thereby making it available for absorption into the blood. Trypsin when applied directly to wounds and ulcers removes dead tissue and improves healing.

Common side effects

Swelling of the mouth, Tightness in the chest, Hives, Difficulty breathing, Itching, Rash, Temporary stinging sensation.other side effects may include pain and burning sensation

Bromelain(90 mg)


Bromelain is used for reducing swelling (inflammation) after surgery or injury, especially of the nose and sinuses. It is also used for hay fever, treating a bowel condition that includes swelling and ulcers (ulcerative colitis), removing dead and damaged tissue after a burn (debridement), preventing the collection of water in the lung (pulmonary edema), relaxing muscles, stimulating muscle contractions, slowing clotting, improving the absorption of antibiotics, preventing cancer, shortening labor, and helping the body to get rid of fat.

How it works

Bromelain is an enzyme obtained from pineapple juice. It causes the body to produce substances that fight pain and swelling (inflammation). It also contains chemicals that interfere with the growth of tumor cells and slow blood clotting.

Common side effects

Changes in menstrual cycles, Breathing difficulties, Nausea, Disturbance of menstrual cycle, Vomiting, Diarrhea, Stomach pain, Increased heart rate

Rutoside(100 mg)


Hemorrhoids, surgical anaesthesia, zollinger-ellison syndrome.

How it works

Not known.

Common side effects

Rashes, Pounding in the ears, Dizziness, Swelling of feet or ankles, Stomach upset, A rapid or irregular heartbeat, Headache, Redness of skin, Itching, Blurred vision, Fluid accumulation in lower legs, Nervousness or restlessness, Weakness or heaviness in the hands or feet

Diclofenac(50 mg)


Diclofenac is used in the treatment of painful conditions of joints, lower back pain, sprains or bone fractures, inflammation of joints (frozen shoulder, gout), pain and swelling following skeletal muscle, dental and other minor surgeries. It is also used in treatment of migraine.

How it works

Diclofenac belongs to group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation.

Common side effects

Toxic epidermal necrolysis, Parenteral:abnormal kidney function, Stomach ulcers or bleeding, Itching and venous thromboembolic events, Epigastric pain


27 Substitutes
Sorted By
    (10 tablet in strip)
    Macleods Pharmaceuticals Pvt Ltd
    Rs. 17.57/tablet
    Rs. 175.75
    same price
    (10 tablet in strip)
    Aristo Pharmaceuticals Pvt Ltd
    Rs. 14.78/tablet
    Rs. 147.75
    save 16% more per tablet
    (10 tablet in strip)
    Corona Remedies Pvt Ltd
    Rs. 16.50/tablet
    Rs. 165
    save 6% more per tablet
    (10 tablet in strip)
    Pharmed Ltd
    Rs. 17.40/tablet
    Rs. 174
    save 1% more per tablet
    (10 tablet in strip)
    Obsurge Pharma P Ltd
    Rs. 15.90/tablet
    Rs. 159
    save 10% more per tablet

Expert advice

  • Do not apply trypsin ointment to fresh blood clots.
  • Avoid contact of trypsin ointment with eyes.
  • Do not start or continue the trypsin tablets/ointment and consult your doctor: If you are pregnant, planning to become pregnant, or are breast-feeding, If you have a wound that contains fresh blood clot.

Frequently asked questions


Q. Is trypsin an enzyme, hormone, protein, endopeptidase?
Trypsin is an enzyme, a protein, an endopeptidase. Trypsin is not a hormone.

Q. Is trypsin acidic or basic?
Trypsin is neither acidic nor basic, it works on optimal operating pH of about 7.5-8.5.

Q. Is trypsin a zymogen, lipase?
Trypsin is a zymogen prior to activation. Trypsin is not a lipase.

Q. Is trypsin found in the stomach? Does trypsin work in the stomach?
Yes trypsin is found in and works in stomach.

Q. Is trypsin harmful? Does trypsin kill cells?
Trypsin is not harmful if used as recommended. Trypsin can damage the cells. In case of any side effects, consult your doctor. 

Q. Does trypsin digest itself? Does trypsin digest proteins? Does trypsin break down starch? Does trypsin break down fats?
Trypsin digests/breaks down proteins into smaller fragments. Trypsin does not breakdown starch or fats. Trypsin can digest itself.

Q. Does trypsin activate pepsinogen? Does trypsin cleave histidine?
Trypsin does not activate pepsinogen. Trypsin does not cleave histidine.

Q. Does trypsin require calcium?
In presence of calcium trypsin remains stabilized which possess greater enzyme activity.


Q. Is bromelain safe?
This drug is safe if used at prescribed dose and duration as advised by your doctor.
Q. Is bromelain safe during pregnancy or breastfeeding?
Bromelain should not be used during pregnancy or breastfeeding. Patients should follow the advice of the doctor regarding its use.
Q. Is bromelain gluten free/ in pineapple?
Yes. Drug is gluten free. However, please refer to package insert of the prescribed brand      before use. Yes, pineapple contains some amount of bromelain in it.
Q. Is bromelain good for gout?
It is not indicated for gout, but may be used in treatment of joint pain. Patients should follow  the advice of the doctor regarding its use.
Q. Is bromelain safe to take before surgery?
No, it is not safe to take before surgery. Patients should follow the advice of the doctor  regarding its use.
Q. How long can I take bromelain for?
Patient should take bromelain for prescribed dose and duration as advised by your doctor.
Q. Can I take bromelain with antibiotics/ibuprofen/prednisone/Coumadin?
No, taking other medicines may alter the effects of bromelain. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does bromelain help with weight loss/swelling/inflammation?
Yes, it is used to reduce swelling, inflammation and helps with weight loss by getting rid of fat.
Q. Does bromelain work?
Yes, it works at prescribed dose and duration for particular disease condition as advised by your doctor.
Q. Does bromelain increase blood pressure/ thin the blood?
Bromelain causing these side effects is rare or uncommon. Always consult your doctor if you experience these side effects.
Q. Does bromelain aid digestion?
It may aid digestion by contraction of smooth muscles, but is used to treat swelling and ulcers (ulcerative colitis). Patients should follow the advice of the doctor regarding its use.


Q. Is diclofenac safe?
Diclofenac (also available as voveran, dynapar) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is diclofenac safe in pregnancy?
Diclofenac should not be used during the first two trimesters (24 weeks) of pregnancy or labor unless the potential benefit to the patient outweighs the potential risk to fetus. Patients should follow the advice of the doctor regarding its use.
Q. Is diclofenac safe in lactation?
Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the benefit of the drug to the mother outweighs the risk to fetus. Patients should follow the advice of the doctor regarding its use.
Q. Is diclofenac nephrotoxic?
Diclofenac can interfere with normal kidney function when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding its uses.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac in asthma.
Q. Is diclofenac banned in India?
Diclofenac is available over-the-counter and it is not banned in India.
Q. Is diclofenac a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, consult your doctor before taking diclofenac if you are already suffering from high blood pressure or any other heart disease.
Q. Does diclofenac induce sleep?
Diclofenac does not induce sleep.

Content on this page was last updated on 29 April, 2016, by Dr. Varun Gupta (MD Pharmacology)