


Enhertu 100mg Injection
Trastuzumab Deruxtecan (100mg)
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Stored between 2-8°C
Enhertu 100mg Injection is used to treat HER2-positive metastatic breast cancer and gastric cancer. These cancers have high levels of the protein called HER2, which promotes cancer cell growth. It binds to HER2 proteins and delivers chemotherapy directly to cancer cells, destroying them while sparing healthy cells.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 01 Oct 2026 | 01:04 AM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 01 Oct 2026 | 01:04 AM (IST)
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Get upto Rs.150 Cashback on minimum transaction of Rs.599/- with Mobikwik UPI (@ikwik).
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General Information
Contains
Trastuzumab Deruxtecan (100mg)
Marketer
AstraZeneca
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English



Product introduction
Enhertu 100mg Injection is used to treat relapsing forms of brain disorders that are caused due to improper working of brain cells
Uses of Enhertu Injection
- Treatment of Stomach cancer
- Treatment of Metastatic breast cancer
Benefits of Enhertu Injection
Treatment of Stomach cancer
Enhertu 100mg Injection is used in the treatment of HER2-positive stomach cancer, particularly those whose cancer has spread or resisted prior treatments. When administered, Enhertu 100mg Injection specifically seeks out HER2-positive cancer cells, delivering chemotherapy directly into these cells while minimizing damage to healthy tissue. This focused approach slows tumor growth and shrinks tumors, offering patients a new line of defense when standard treatments are no longer effective. It improves disease control and helps enhance the patient's survival and quality of life.
Enhertu 100mg Injection is used in the treatment of HER2-positive stomach cancer, particularly those whose cancer has spread or resisted prior treatments. When administered, Enhertu 100mg Injection specifically seeks out HER2-positive cancer cells, delivering chemotherapy directly into these cells while minimizing damage to healthy tissue. This focused approach slows tumor growth and shrinks tumors, offering patients a new line of defense when standard treatments are no longer effective. It improves disease control and helps enhance the patient's survival and quality of life.
Treatment of Metastatic breast cancer
Enhertu 100mg Injection is an effective treatment, especially for patients whose cancer has spread or continued to grow despite other treatments. It works by attaching to HER2 proteins on cancer cells and delivering chemotherapy straight into these cells. This makes the treatment work better against the cancer while causing less harm to healthy cells nearby. By specifically targeting cancer cells, Enhertu 100mg Injection can help slow down or even shrink the spread of cancer, giving patients a longer time before the disease progresses and improving their quality of life, even in advanced stages.
Enhertu 100mg Injection is an effective treatment, especially for patients whose cancer has spread or continued to grow despite other treatments. It works by attaching to HER2 proteins on cancer cells and delivering chemotherapy straight into these cells. This makes the treatment work better against the cancer while causing less harm to healthy cells nearby. By specifically targeting cancer cells, Enhertu 100mg Injection can help slow down or even shrink the spread of cancer, giving patients a longer time before the disease progresses and improving their quality of life, even in advanced stages.
Side effects of Enhertu Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Enhertu
- Nausea
- Fever
- Fatigue
- Vomiting
- Hair loss
- Constipation
- Diarrhea
- Decreased appetite
- Musculoskeletal (bone, muscle or joint) pain
- Abdominal pain
- Decreased white blood cell count
- Decreased hemoglobin
- Decreased white blood cell count (neutrophils)
- Decreased white blood cell count (lymphocytes)
- Low blood platelets
- Increased aspartate aminotransferase
- Increased alanine aminotransferase
- Increased alkaline phosphatase level in blood
- Decreased potassium level in blood
- Increased bilirubin in the blood
How to use Enhertu Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Enhertu Injection works
Enhertu 100mg Injection finds cancer cells that have a lot of the HER2 protein on their surface. These HER2-positive cells grow and multiply faster than normal cells. Once it attaches to the HER2-positive cancer cell, it’s pulled inside. Inside the cancer cell, Enhertu 100mg Injection causes damage and kills the cancer cell directly without affecting nearby healthy cells.
Quick tips
- For best results, ensure Enhertu 100mg Injection infusions are received consistently every three weeks without missed doses.
- Report any side effects, even mild ones, to your doctor so they can help you prevent or manage them.
- Since Enhertu 100mg Injection can lower your white blood cell count, minimizing your exposure to infections is important. Wash your hands frequently, avoid crowded places when possible, and clean any minor cuts or wounds.
- Fatigue is a common side effect with Enhertu 100mg Injection, so avoid strenuous activities, especially if your energy levels are low. However, light activities like short walks or stretching can boost energy levels and reduce fatigue.
- Drink plenty of water and eat balanced, nutritious meals to help support your immune system.
- Cancer treatment can be challenging, so remember that emotional support is just as important as physical care. Reach out to family, friends, or support groups, and let your doctor know if you need additional resources to support your mental health during treatment.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Enhertu 100mg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Enhertu 100mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Enhertu 100mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Enhertu 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Enhertu 100mg Injection in patients with kidney disease. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Enhertu 100mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions
Enhertu 100mg Injection is a targeted cancer therapy specifically used to treat HER2-positive metastatic breast cancer and HER2-positive stomach (gastric) cancer. It is particularly helpful for patients whose cancer has spread or returned after previous treatments.
Enhertu 100mg Injection targets the HER2 protein found on certain cancer cells. It combines an antibody with a chemotherapy drug, binding to HER2-positive cancer cells and delivering chemotherapy directly into the cell. This helps kill the cancer cells more effectively while sparing healthy cells.
Enhertu 100mg Injection is given through an intravenous (IV) infusion by a doctor or a nurse, typically every three weeks. It is vital to follow this schedule to allow the treatment to work optimally.
Yes. It’s essential to attend all scheduled treatments and follow any advice from your doctor. Staying hydrated, eating a balanced diet, and informing your doctor about any side effects or symptoms can also help you manage the treatment more effectively.
Avoid alcohol, as it may stress your liver, which is processing the medication. Also, avoid activities that increase the risk of injury, as low blood cell counts can make infections more dangerous. Discuss any new medications or supplements with your doctor to ensure they don’t interfere with your treatment.
Yes, some patients may experience serious side effects. One rare but severe side effect is interstitial lung disease (ILD), which causes inflammation in the lungs. Symptoms of ILD include coughing, shortness of breath, and difficulty breathing. If you experience these symptoms, contact your doctor immediately.
Enhertu 100mg Injection is not safe for pregnant women, as it may harm the unborn baby, and breastfeeding is not recommended during treatment. Women should discuss pregnancy prevention options with their doctors before starting Enhertu 100mg Injection.
The duration of treatment varies depending on individual responses and tolerance to the medication. Your doctor will monitor your progress and decide the best duration for your treatment with Enhertu 100mg Injection.
Enhertu 100mg Injection is not recommended for people with certain lung conditions or severe allergic reactions to trastuzumab-based drugs. It is also not suitable for pregnant or breastfeeding women. Your doctor will review your medical history to determine if Enhertu 100mg Injection is appropriate for you.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Monoclonal Antibodies (mAbs)
References
- Trastuzumab deruxtecan [Prescribing Information]. Basking Ridge, NJ: Daiichi Sankyo, Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Summary of Product Characteristics]. Munich, Germany: Daiichi Sankyo Europe GmbH; 2023. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Product Monograph]. Mississauga, Ontario: AstraZeneca Canada Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Enhertu (Trastuzumab deruxtecan) [Product Information]. 2024. [Accessed 30 Oct. 2024] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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