Endol Plus 650mg/10mg Tablet

Paracetamol (650mg)+ Promethazine (10mg)

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Endol Plus 650mg/10mg Tablet is a combination medicine used to treat common cold symptoms. It provides temporary relief from congestion and stuffiness in the nose. It also helps to relieve allergy symptoms like runny nose, sneezing, throat irritation, and watery eyes.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Feb 2026 | 11:44 AM (IST)

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General Information

Contains

Paracetamol (650mg)+ Promethazine (10mg)

Marketer

Bangalore Antibiotics & Biologicals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Endol Plus 650mg/10mg Tablet is taken with or without food in a dose and duration as advised by the doctor. It is better to take it with food to avoid stomach upset. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effect is allergic reactions which are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It can also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before taking it, you should tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Endol Plus Tablet

Treatment of Common cold

Benefits of Endol Plus Tablet

Treatment of Common cold
Endol Plus 650mg/10mg Tablet is a combination medicine that effectively relieves symptoms of the common cold, such as a blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier.

Endol Plus 650mg/10mg Tablet is safe and effective. It usually starts to work within a few minutes, and the effects can last up to several hours. Take it as prescribed by your doctor, and do not stop using it unless you are advised otherwise.

Side effects of Endol Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Endol Plus

Sleepiness
Allergic reaction

How to use Endol Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endol Plus 650mg/10mg Tablet may be taken with or without food.

How Endol Plus Tablet works

Endol Plus 650mg/10mg Tablet is a combination of two medicines: Paracetamol and Promethazine which relieve common cold symptoms.

Quick tips

Endol Plus 650mg/10mg Tablet is prescribed to get relief from symptoms of common cold.
Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
Call your doctor if your symptoms have not improved within seven days of treatment.
Inform your doctor if you are taking any other medications for cold.
Along with taking Endol Plus 650mg/10mg Tablet do the following simple tips at home to get relief:
1. Steam inhalation.
2. Gargling with warm saltwater.
3. Apply vapor rubs on chest, back if needed. Take enough rest.
4. Take warm food and fluid only. Ensure adequate fluid intake.
5. Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcases, etc.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Endol Plus 650mg/10mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Endol Plus 650mg/10mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Endol Plus 650mg/10mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
For prolonged use and repeated doses of Endol Plus 650mg/10mg Tablet, observe the baby for excessive sleepiness.

Driving

CONSULT YOUR DOCTOR

It is not known whether Endol Plus 650mg/10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Endol Plus 650mg/10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them.

Liver

UNSAFE

Endol Plus 650mg/10mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Endol Plus 650mg/10mg Tablet used for?

Endol Plus 650mg/10mg Tablet is used to treat the symptoms of the common cold and flu, such as a runny nose, cough, sneezing, and watery eyes. It is also one of the commonly used medicines in chickenpox for symptomatic relief.

Will Endol Plus 650mg/10mg Tablet make me drowsy?

Promethazine, present in Endol Plus 650mg/10mg Tablet, causes significant drowsiness and sleepiness. Because of this, it is an excellent choice for nighttime relief of cold and flu symptoms, as it can help you get the rest you need to recover. You should not drive or operate heavy machinery after taking it.

How quickly will Endol Plus 650mg/10mg Tablet start to work?

You can expect to feel relief from pain and fever within about 30 to 60 minutes of taking Endol Plus 650mg/10mg Tablet. The sedating effects of this medicine will typically begin within about 20 minutes and reach their peak in a couple of hours, helping you to fall asleep.

Can I use Endol Plus 650mg/10mg Tablet for motion sickness or nausea?

Endol Plus 650mg/10mg Tablet can be used to prevent and treat nausea and vomiting, including motion sickness. It can also be helpful if your nausea is accompanied by a headache or general discomfort. However, it is advised to consult a doctor for the proper dose and duration for safer and desired results.

What should I tell my doctor before I start taking Endol Plus 650mg/10mg Tablet?

Before starting Endol Plus 650mg/10mg Tablet, you should inform your doctor if you have a history of breathing problems (like asthma or COPD), glaucoma, or difficulty urinating due to an enlarged prostate. This medicine can sometimes make these conditions worse, so your doctor will need to determine if it is safe for you.

Can Endol Plus 650mg/10mg Tablet be used to treat a cough?

While Endol Plus 650mg/10mg Tablet is not a primary cough suppressant, the antihistamine effect of promethazine present in this medicine can help to reduce a cough that is caused by post‑nasal drip from allergies or a cold. It helps to dry up the mucus that can tickle the back of your throat and make you cough.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bangalore Antibiotics & Biologicals Pvt Ltd
Address: 5/235,B, 1st Floor, Thistle House, PHED Road, Eranhipalam, Civil Station P.O, Calicut - 673 020, Kerala, India.

Vendor Details

Country of origin: India

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Endol Plus 650mg/10mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Endol Plus Tablet

Benefits of Endol Plus Tablet

Side effects of Endol Plus Tablet

How to use Endol Plus Tablet

How Endol Plus Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Endol Plus 650mg/10mg Tablet used for?

Will Endol Plus 650mg/10mg Tablet make me drowsy?

How quickly will Endol Plus 650mg/10mg Tablet start to work?

Can I use Endol Plus 650mg/10mg Tablet for motion sickness or nausea?

What should I tell my doctor before I start taking Endol Plus 650mg/10mg Tablet?

Can Endol Plus 650mg/10mg Tablet be used to treat a cough?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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