Durapain 75mg/50mg Tablet

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Durapain 75mg/50mg Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.

Durapain 75mg/50mg Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects on of this medicine include nausea, vomiting, indigestion, heartburn, stomach pain, loss of appetite, and dryness in mouth. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent the side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Durapain Tablet

Benefits of Durapain Tablet

In Pain relief

Durapain 75mg/50mg Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis and osteoarthritis. It also helps to manage short term symptoms such as muscle and back pain, toothache, or pain in the ear and throat. It works by reducing substances in the body that cause pain and swelling. By reducing pain, it improves the quality of your life.

Side effects of Durapain Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Durapain

  • Nausea
  • Vomiting
  • Indigestion
  • Heartburn
  • Stomach pain
  • Loss of appetite
  • Dryness in mouth
  • Dizziness
  • Sleepiness

How to use Durapain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Durapain 75mg/50mg Tablet is to be taken with food.

How Durapain Tablet works

Durapain 75mg/50mg Tablet is a combination of two medicines: Diclofenac and Tramadol, which relieves severe pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tramadol is an opioid which works by blocking transmission of pain signals to the brain to lower pain perception.

Safety Advice

It is unsafe to consume alcohol with Durapain 75mg/50mg Tablet.
Durapain 75mg/50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Durapain 75mg/50mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Durapain 75mg/50mg Tablet may cause side effects which could affect your ability to drive.
Durapain 75mg/50mg Tablet may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Durapain 75mg/50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Durapain 75mg/50mg Tablet may be needed. Please consult your doctor.
Durapain 75mg/50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Durapain 75mg/50mg Tablet may be needed. Please consult your doctor.

What if you forget to take Durapain Tablet?

If you miss a dose of Durapain 75mg/50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Durapain 75mg/50mg Tablet
Dibol 75 mg/50 mg Tablet
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Tramazide D 75mg/50mg Tablet
Ikon Remedies Pvt Ltd
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Dolinsta Tablet
Indoco Remedies Ltd
44% cheaper
Dibol S Tablet
Ajanta Pharma Ltd
36% cheaper

Quick Tips

  • Durapain 75mg/50mg Tablet is used to treat various painful conditions.
  • Durapain 75mg/50mg Tablet should be taken with, or straight after, a meal or snack. This helps to reduce the risk of stomach upset.
  • Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
  • Keep sipping water or have chewing sugar-free gum in order to relieve dryness in the mouth.
  • You might experience nausea, ask your doctor to prescribe you an antiemetic (anti-sickness medicine) if it troubles you.
  • Inform your doctor if you have a history of depression or taking any anti-depressants.
  • Seek medical attention right away if you have symptoms, such as agitation, hallucinations,  sweating, shivering, fast heart rate, muscle stiffness, twitching, or loss of coordination.

Fact Box

Habit Forming
Therapeutic Class

Patient Concerns

As i have an operation of joints so my doctor gave me 3 tablets to reduce swelling and pain bt as i take that tablets it uses to vomit out so what should i do. Tableta are pantop 40, phlogam and durapain.
Dr. Akshat Goel
Reduce dose of Durapain to halfOr you can take Tab Kinedol-EF in place of Durapain
One of my teeth is sensitive. It some times pains
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief
Do you have any questions related to Durapain 75mg/50mg Tablet ?

User Feedback


Q. Can I discontinue the medication when my pain is relieved?

Durapain 75mg/50mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Durapain 75mg/50mg Tablet should be continued if you are advised by the doctor to do so.

Q. Can the use of Durapain 75mg/50mg Tablet cause constipation?

Yes, the use of Durapain 75mg/50mg Tablet can cause constipation. Talk to your doctor about treating constipation if it persists for a long time.

Q. Are there any specific contraindications associated with the use of Durapain 75mg/50mg Tablet?

Durapain 75mg/50mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. Durapain 75mg/50mg Tablet can cause problems when used with medicines that can cause sleepiness or MAO inhibitors (certain medicines that are used in the treatment of depression or Parkinson’s disease). Durapain 75mg/50mg Tablet should not be used in patients who are suffering from severe liver disease or epilepsy.

Q. Can the use of Durapain 75mg/50mg Tablet cause damage to kidneys?

Yes, long-term use of Durapain 75mg/50mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can the use of Durapain 75mg/50mg Tablet cause dry mouth?

Yes, the use of Durapain 75mg/50mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.

Q. What are the instructions for the storage and disposal of Durapain 75mg/50mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:External Link
  3. Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. FDA approved prescribing information. Tramadol hydrochlorid; 1995 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of Origin: India

We do not facilitate sale of this product at present


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