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MDS (Oral Pathology & Microbiology), BDS
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MD (Pharmacology), MBBS
Last updated on:
18 Jul 2019 | 02:57 PM (IST)
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Durapain 75mg/50mg Tablet


Uses of Durapain Tablet

Durapain Tablet side effects

  • Nausea
  • Vomiting
  • Indigestion
  • Heartburn
  • Stomach pain
  • Loss of appetite
  • Dryness in mouth
  • Dizziness
  • Sleepiness

How to use Durapain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Durapain 75mg/50mg Tablet is to be taken with food.
This will help to avoid acidity and heartburn.

How Durapain Tablet works

Durapain 75mg/50mg Tablet is a combination of two medicines: Diclofenac and Tramadol, which relieves severe pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tramadol is an opioid which works by blocking transmission of pain signals to the brain to lower pain perception.

Durapain Tablet related warnings

It is unsafe to consume alcohol with Durapain 75mg/50mg Tablet. Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Durapain 75mg/50mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Durapain 75mg/50mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Do not drive unless you are feeling well.
Durapain 75mg/50mg Tablet may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Durapain 75mg/50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Durapain 75mg/50mg Tablet may be needed. Please consult your doctor.
Durapain 75mg/50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Durapain 75mg/50mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Durapain 75mg/50mg Tablet
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Patient Concerns

Questions Related to Durapain

As i have an operation of joints so my doctor gave me 3 tablets to reduce swelling and pain bt as i take that tablets it uses to vomit out so what should i do. Tableta are pantop 40, phlogam and durapain.
Dr. Akshat Goel
Bone & Joint Specialist
Reduce dose of Durapain to halfOr you can take Tab Kinedol-EF in place of Durapain
I am experiencing neck to arm problem. I cant bear the pain. X ray is normal. When i lay down to the bed then its ok, but when i sit or stand within 4 min. I get neck pain and my arm is just hanged. What to do. I m taking lyrica 75 mg. , duzela, durapain, contramal dt and robinaxol. Then also no effect on my pain. What to do
Dr. Vikas Sharma
do mri cervical spine; show to neurologist
Do you have any questions related to Durapain 75mg/50mg Tablet?

User Feedback


Q. Can I discontinue the medication when my pain is relieved?

Durapain is usually used for short term and can be discontinued when your pain is relieved. However, Durapain should be continued if you are advised by the doctor to do so.

Q. Can the use of Durapain cause constipation?

Yes, the use of Durapain can cause constipation. Talk to your doctor about treating constipation if it persists for a long time.

Q. Are there any specific contraindications associated with the use of Durapain?

Durapain should be avoided in patients with known allergy to any of the components or excipients of this medicine. Durapain can cause problems when used with medicines that can cause sleepiness or MAO inhibitors (certain medicines that are used in the treatment of depression or Parkinson’s disease). Durapain should not be used in patients who are suffering from severe liver disease or epilepsy.

Q. Can the use of Durapain cause damage to kidneys?

Yes, long-term use of Durapain can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can the use of Durapain cause dry mouth?

Yes, the use of Durapain can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.

Q. What are the instructions for the storage and disposal of Durapain?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:External Link
  3. Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. FDA approved prescribing information. Tramadol hydrochlorid; 1995 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:External Link
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16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
We do not facilitate sale of this product at present


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