DURANZO 50 MG/50 MG TABLET

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Ajanta Pharma Ltd

Composition for DURANZO 50 MG/50 MG TABLET

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Primarily used for

Potentiallyunsafewith
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Alcohol
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Pregnancy
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Substitutes for DURANZO 50 MG/50 MG TABLET

CODERAN 50 MG/50 MG TABLET
Novartis India Ltd
₹8.8/tablet
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Medicine Overview of DURANZO 50 MG/50 MG TABLET

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Uses of Diclofenac

Diclofenac is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
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Side effects of Diclofenac

Common

Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.

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How to use Diclofenac

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How DURANZO 50 MG/50 MG TABLET works

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
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Uses of Codeine

Codeine is used for pain and dry cough.
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Side effects of Codeine

Common

Sweating, Headache, Dizziness, Sleepiness, Vomiting, Weakness, Dehydration, Lightheadedness, Nausea, Edema, Dry mouth, Fatigue, Anemia, Sedation, Constipation.

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How to use Codeine

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How DURANZO 50 MG/50 MG TABLET works

Codeine decreases the perception of pain by blocking the transmission of pain signals to the brain.

In Depth Information on DURANZO 50 MG/50 MG TABLET

Expert advice for Diclofenac

  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • It should be taken with food or milk to avoid getting an upset stomach.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Diclofenac can raise a risk of blood clots, heart attack, or a stroke.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Expert advice for Codeine

Do not drink alcohol while you are on codeine medication. Take the drug with meals or a snack to prevent stomach upset. Do not drive or operate machinery. Do not use for pain relief in children and adolescents (0-18 years of age) as it may cause serious breathing problems.Codeine can be habit forming, so do not take larger doses or for longer duration than what is prescribed by your doctor. Codeine commonly cause a sudden drop in blood pressure, especially when you change positions, such as going from sitting to standing. Be careful since you can feel dizzy or fall. If symptoms continue for more than a week, you may need to change the dose or medicine after consulting your doctor.Always consult your doctor if you are using drugs or have used drugs in the past, are taking or have taken within the last two weeks, monoamine oxidase inhibitors (MAOIs) such as moclobemide, or phenelzine used in the treatment of depression.Codeine may cause constipation. Consult your doctor about changing your diet and using other medications to treat or prevent constipation.Doctor’s advice should be considered in any of following disease conditions
  • Attacks of asthma, bronchitis or emphysema, cor-pulmonale.
  • Severe obesity.
  • Severely deformed spine, mental illness brought on by an infection.
  • Liver problems, kidney problems, problems with your bile duct.
  • Enlarged prostate gland (in men) or difficulty in passing urine.
  • Under-active thyroid or adrenal gland.
  • Low blood pressure.
  • Inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis or a blockage in the bowel, fits.
  • Myasthenia gravis.
Warnings
Special precautions for DURANZO 50 MG/50 MG TABLET
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Alcohol
CAUTION
Duranzo 50 mg/50 mg tablet may cause excessive drowsiness and calmness with alcohol.

Taking diclofenac with alcohol can increase your risk of stomach bleeding.
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Pregnancy
WEIGH RISKS VS BENEFITS
Duranzo 50 mg/50 mg tablet is unsafe to use during pregnancy.

There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
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Lactation
CAUTION
Duranzo 50 mg/50 mg tablet is probably unsafe to use during
breastfeeding. Please consult your doctor.
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Driving
CAUTION
Patients should not drive or operate machinery if they get affected symptoms like dizziness, drowsiness, fatigue, visual disturbances.

Caution is advised when driving or operating machinery.
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Kidney
CAUTION
Caution should be used in patients with renal impairment.
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Liver
There is no data available. Please consult doctor before consuming the drug.

Patient Concerns

Frequently asked questions for DURANZO 50 MG/50 MG TABLET

Frequently asked questions for Diclofenac

Q. What is the difference between Diclofenac and naproxen?
In research studies, naproxen has been found to have lesser cardiovascular events like stroke and heart attack than Diclofenac. Another key variations naproxen may be more likely to be recommended for the treatment of inflammatory conditions in young patients as compared to Diclofenac.
Q. What is the difference between Diclofenac and ketoprofen?
Although both these agents are non-steroidal anti-inflammatory drugs (NSAIDs), there is a subtle difference in the way they act. Ketoprofen blocks the Cyclo-oxygenase (COX) enzyme without any preference for blocking of any one of this enzyme subtypes. Diclofenac has the preference to block COX-2 subtype of Cyclooxygenase enzyme. Blocking of COX reduces prostaglandins (chemicals naturally produced by the body that is responsible for pain and inflammation).
Q. Can Diclofenac be used along with warfarin?
No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.
Q. Are Diclofenac and ibuprofen same?
No. Diclofenac and Ibuprofen are different medicines but they both belong to the same class of drugs i.e. Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Both are commonly used as painkillers.
Q. Is Diclofenac a painkiller?
Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.
Q. Is Diclofenac a narcotic?
No. Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
Q. Can I use Diclofenac along with vitamins?
Yes. There is no known interaction between Diclofenac and Vitamins.
Q. Can Diclofenac be used for the treatment of hepatitis?
No. Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.
Q. Can Diclofenac be used after C-section?
Yes. Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.
Q. What is the difference between Diclofenac and baclofen?
Diclofenac is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Baclofen is a depressant of the nervous system, used to relax the muscles and also used in to reduce pain. Baclofen is used for the treatment of spinal cord injury, cerebral palsy, and multiple sclerosis.
Q. What is the difference between Diclofenac and lidocaine?
Diclofenac is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Lidocaine (also known as xylocaine and lignocaine) is a medication primarily used to numb tissue in a specific area before any surgical procedure and is also used to treat ventricular tachycardia (a condition where the beating rhythm of the heart gets disturbed.
Q. What is the Cmax of Diclofenac?
Cmax of Diclofenac (50 mg) is 3.9 µmol/l.
Q. Which is the best choice between Diclofenac and aceclofenac?
The researcher has proved that aceclofenac is a better alternative to Diclofenac with fewer side effects, especially in the treatment of osteoarthritis, ankylosing spondylitis. Both Aceclofenac and Diclofenac are NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and used as painkillers.
Q. What is Diclofenac SR?
Diclofenac SR refers to the 'Sustained Release' preparation of Diclofenac. Sustained release preparations are designed to release Diclofenac at a known rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects. This decreases the number of tablets you need to swallow with almost similar benefits.
Q. What is the half-life of Diclofenac?
The half-life of Diclofenac is 1-2 hours. This is the time required for the concentration or amount of drug in the body to be reduced by one-half.
Q. Which is the best choice between Diclofenac and ibuprofen for back pain?
Both Diclofenac and Ibuprofen can be used for back pain.
Q. Which is the best choice between Diclofenac and ibuprofen for a toothache?
Both Diclofenac and Ibuprofen can be used for toothache. Currently, there are not many studies which can identify the best treatment between the these two agents. However according to one study, a combination of Diclofenac with paracetamol has been found to be better then a combination of Ibuprofen and paracetamol.
Q. What is the difference between Diclofenac and meloxicam?
Meloxicam has been found to have fewer gastrointestinal side effects than Diclofenac and its use is associated with an increased risk of cardiovascular events such as heart attack and stroke.
Q. Can I take Diclofenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).
Q. Can I take Diclofenac along with vitamins?
Yes. There is no known interaction between Diclofenac and Vitamins.
Q. Can I take Diclofenac while I am on thyroxine?
Yes. There is no known interaction between Diclofenac and Thyroxine.
Q. What is the difference between Diclofenac potassium and Diclofenac sodium?
Diclofenac exists in two forms - the sodium salt (Diclofenac sodium) and the potassium salt (Diclofenac potassium). Each has the same amount of Diclofenac base - the main difference is that Diclofenac potassium is slightly more soluble in water than Diclofenac sodium.
Q. Can Diclofenac be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like Diclofenac can lead to a risk of increased bleeding tendency. So refrain from taking piroxicam or any pain killer in the case of any fever with joint pain. Consult your doctor before starting Diclofenac.
Q. Where is Diclofenac metabolised?
Diclofenac is metabolised in the liver.
Q. How much of Diclofenac is absorbed?
Diclofenac is rapidly and completely absorbed from tablets. Food intake does not affect absorption.
Q. Why Diclofenac should be stopped before surgery?
Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.
Q. What are the contraindications for Diclofenac?
Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, active ulcer in the stomach, bleeding from stomach, allergic reactions (including asthma, urticaria, rhinitis etc) to other NSAIDs like Aspirin, Severe heart failure, liver failure, kidney failure and a history of heart attack.
Q. Can Diclofenac affect the chance of conceiving?
Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Why does Diclofenac cause an ulcer?
Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.
Q. Why is Diclofenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. What is Diclofenac ER?
ER is a short name for 'Extended Release'. Diclofenac ER tablets deliver the drug Diclofenac for a prolonged period of time. This, in turn, decreases the number of tablets you swallow per day.
Q. Is Diclofenac good for back pain?
Yes. Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.
Q. Can I use Diclofenac during my fever treatment?
Yes. Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.
Q. Can I use Diclofenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.
Q. Can I use Diclofenac to treat UTI?
Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.
Q. Can Diclofenac cause sedation?
Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.
Q. Can I take Diclofenac for kidney stones?
Yes. Diclofenac is given to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.
Q. Can I use Diclofenac for nerve pain?
Yes. Studies have shown Diclofenac (topical preparations) to be of use in nerve pain like Post-Herpetic pain.
Q. Can I use Diclofenac for eye management?
Yes. Diclofenac eye drops can be used to treat non-bacterial inflammation,e.g. post-operative state. Diclofenac eye drops have also been used to manage pain for traumatic corneal abrasion.
Q. Can I use Diclofenac for the treatment of arthritis?
Yes. Diclofenac belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.
Q. Can I use Diclofenac with diuretics?
No. Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can I use Diclofenac with mifepristone?
No. Effect of mifepristone may be reduced by NSAIDs like Diclofenac. Mifepristone is used for medical abortion.
Q. Can I use Diclofenac with lithium?
No. Diclofenac may increase the blood level of lithium, causing increased side effect.
Q. Can smoking be harmful over diclofenac?
Yes. Smoking is a known risk factor causing an ulcer in the stomach. Diclofenac too can cause ulceration of stomach as a side effect. Both together may increase the chance of forming ulcer in the stomach and bleeding. Therefore it is advised to quit smoking while on Diclofenac therapy.
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Frequently asked questions for Codeine

Q. Is codeine legal in India?
Yes, however codeine containing tablets require prescription in India
Q. Is codeine addictive?
Codeine may cause addiction when consumed for longer duration. Patients should follow the advice of the doctor regarding its use
Q. Is codeine a narcotic/hydrocodone/morphine/depressant?
Codeine is a naturally occurring form of morphine and called as narcotic. Hydrocodone is derived form of codeine. Codeine is not a depressant drug
Q. Is codeine strong?
It depends on the dose. Patients should follow the advice of the doctor regarding its use
Q. Is codeine/Corex/Phensedyl over the counter or banned in India?
No, it is available in India with doctor's prescription only
Q. Is codeine/Corex bad or harmful?
It is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Corex a drug?
No, Corex is a cough syrup which contains codeine as one of its component
Q. What is Paracodin/Paracodin tablets/Paracodin 10 mg/Paracodol/Paracodina/Paracodin drops/Phensedyl/Phensedyl cough syrup used for?
These are the trade names of codeine containing products. Your doctor may prescribe it (depending on the disease condition) for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome
Q. Can I take codeine for flu/headache/toothache/cold/back pain/tonsillitis/migraine/menstrual cramps/stomach pain?
Codeine is specifically used for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome. Patients should follow the advice of the doctor regarding its use
Q. Can I take codeine with naproxen/paracetamol/ibuprofen/advil/ warfarin/metronidazole/hydrocodone/diclofenac/ amoxicillin?
You can take codeine with paracetamol/ibuprofen/ Advil/ warfarin/ diclofenac/amoxicillin/naproxen. Taking metronidazole and hydrocodone may alter the effects of codeine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does codeine expire?
Codeine containing tablets are available with mention of expiry date on it. Before taking medicine, patient should consult pharmacist or doctor
Q. Does codeine make you high/tired/fat/awake/ sleep/constipate/thin blood/headache?
Codeine causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects
Q. Does codeine have acetaminophen in it?
No, it does not contain acetaminophen in it. However, your doctor may prescribe codeine along with acetaminophen.
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