Duoflam 400mg/500mg Tablet is a combination of two medicines: Ibuprofen and Paracetamol/Acetaminophen. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Duoflam Tablet related warnings

Alcohol

UNSAFE

It is unsafe to consume alcohol with Duoflam 400mg/500mg Tablet Taking Ibuprofen+Paracetamol/Acetaminophen with alcohol can cause liver damage.

Pregnancy

CONSULT YOUR DOCTOR

Duoflam 400mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Lactation

SAFE IF PRESCRIBED

Duoflam 400mg/500mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Duoflam 400mg/500mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Duoflam 400mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Duoflam 400mg/500mg Tablet may be needed. Please consult your doctor.
Use of Duoflam 400mg/500mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.

Liver

CAUTION

Duoflam 400mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Duoflam 400mg/500mg Tablet may be needed. Please consult your doctor.
However, the use of Duoflam 400mg/500mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Alternate Brands

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Expert Advice

You have been prescribed this combination medicine to relieve pain, inflammation, and fever.
Take it with food to avoid getting an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to stomach bleeding and kidney problems.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Duoflam 400mg/500mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Patient Concerns

Questions Related to Duoflam

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First step is to assess the severity of the problem. A Physical examination in clinic is required for that. Based on findings a treatment plan will be adviced

Very severe pain in legs. From upper thighs upto knees. I took one Combiflame yesterday morning and one yesterday evening with oil massage but relief for just short period Its so un bearable again I feel like crying. No fever as yet.today took one Voveron sr100 at 4.30 am but No respite.I am really worried pls advice

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Do Hot Fomentation and apply Dynapar QPS spray and take Tab Myospas-D thrice daily and Tab Flotrip-forte thrice daily and Cap Nurokind-Gold twice daily for 5 days.Avoid forward bending and Avoid lifting heavy weightIn extreme pain take one tablet of NAXDOM-500 for immediate pain relief

Do you have any questions related to Duoflam 400mg/500mg Tablet?

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User Feedback

Patients taking Duoflam 400mg/500mg Tablet

Twice A Day

45%

Once A Day

31%

Thrice A Day

22%

What are you using Duoflam Tablet for?

Others

50%

Fever

50%

FAQs

Q. What is Duoflam?

Duoflam is a combination of two medicines: Ibuprofen and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of certain chemical substances in the body that cause pain and inflammation.

Q. Is it safe to use Duoflam?

Duoflam is safe for most of the patients. However, in some patients, it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea, and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem due to the medication.

Q. Can I stop taking Duoflam when my pain is relieved?

Duoflam should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.

Q. Can the use of Duoflam cause nausea and vomiting?

Yes, the use of Duoflam can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Q. Can the use of Duoflam cause dizziness?

Yes, the use of Duoflam can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines.

Q. Are there any specific contraindications associated with the use of Duoflam?

The use of Duoflam is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.

Q. Is Duoflam helpful in relieving stomach pain?

No, Duoflam preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Q. Can the use of Duoflam cause damage to kidneys?

Yes, the long-term use of Duoflam can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lower the levels of prostaglandins in the body leading to kidney damage because of long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Is it safe to take a higher dose of Duoflam than recommended?

No, taking a higher than the recommended dose of Duoflam can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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References

Drugs.com. Ibuprofen. [Accessed 02 Apr. 2019] (online) Available from:
Paracetamol. Barnstaple, Devon: Actavis UK Ltd.; 1980 [revised 23 Dec. 2016]. [Accessed 02 Apr. 2019] (online) Available from:
Ibuprofen. North Harrow, Middlesex: Accord Healthcare Limited; 2016 [revised 16 Mar. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:

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