Dotrasulide 40mg/100mg Tablet is a combination medicine used in the treatment of abdominal pain. It works effectively to reduce abdominal pain, bloating, discomfort and cramps by relaxing the muscles of the stomach and gut. It also blocks certain chemical messengers that cause pain, inflammation and fever.

Dotrasulide 40mg/100mg Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are diarrhea, nausea, vomiting, dryness in the mouth, feeling thirsty, and increased liver enzymes. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Note: As per the Ministry of Health and Family Welfare, Dotrasulide 40mg/100mg Tablet is banned for children under 12 years of age.

Uses of Dotrasulide Tablet

Abdominal pain

Side effects of Dotrasulide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dotrasulide

Vomiting
Dryness in mouth
Nausea
Vertigo
Insomnia (difficulty in sleeping)
Hypotension (low blood pressure)
Sweating
Constipation

How to use Dotrasulide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dotrasulide 40mg/100mg Tablet is to be taken with food.

How Dotrasulide Tablet works

Dotrasulide 40mg/100mg Tablet is a combination of two medicines: Drotaverine and Nimesulide, which relieves abdominal pain. Drotaverine is an anti-spasmodic medicine which relieves spasms associated with smooth muscles. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Dotrasulide 40mg/100mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Dotrasulide 40mg/100mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Dotrasulide 40mg/100mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Dotrasulide 40mg/100mg Tablet may cause side effects which could affect your ability to drive.
As Dotrasulide 40mg/100mg Tablet may cause vertigo.

Kidney

CAUTION

Dotrasulide 40mg/100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Dotrasulide 40mg/100mg Tablet may be needed. Please consult your doctor.
Use of Dotrasulide 40mg/100mg Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Dotrasulide 40mg/100mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Dotrasulide 40mg/100mg Tablet

₹2.91/Tablet

Nobel Spas 40mg/100mg Tablet

Mankind Pharma Ltd

₹9.4/tablet

223% costlier

Colibest Tablet

BestoChem Formulations India Ltd

₹5.97/tablet

105% costlier

Ospas 40mg/100mg Tablet

Auspi Medicaments

₹2.71/tablet

7% cheaper

Inlid Spas 40mg/100mg Tablet

Donnel Healthcare Pvt Ltd

₹3.68/tablet

26% costlier

Mielid Spas 40mg/100mg Tablet

Mits Healthcare Pvt Ltd

₹5.33/tablet

83% costlier

View all substitutes

Quick tips

You have been prescribed Dotrasulide 40mg/100mg Tablet to get relief from abdominal pain.
Dotrasulide 40mg/100mg Tablet should be taken with, or straight after, a meal or snack. This helps to reduce the risk of stomach upset.
Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
Drink plenty of water while taking Dotrasulide 40mg/100mg Tablet in case you experience diarrhea as its side-effect.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Actually i am surffering from kidney stone and because kidney stone i am suffering from stomache and also i am having pain in bladder

Dr. Sunil Sekhri

Diabetology

Kidney stone cause sever abdominal pain. consult a Surgeon

Left abdominal pain from last 3 days.Especially when I take a large breath(inhale)

Dr. Sunil Sekhri

Diabetology

All abdominal pain patients need to be seen and treated in clinic

Hello , sir since this past december i am facing problems like headache ,eye pain , weakness and sometimes abdominal pain .i want to tell you that 7 months ago i joined gym and i started to eat 25 chapatis and 100 gms of roasted peanuts daily to gain weight and i also ate used protien powder for about a month so i cannot figure out which thing caused illness or i am just depressed

Dr. Sunil Sekhri

Diabetology

Abdominal pain could be because of excess diet. Other symptoms are non specific.

I'm having stomach pain since the last few weeks. I also went to the doctor for a checkup and was diagnosed with enteritis and was given medication for some few days. I was fine then but after a week pain has started again. Please tell the right medication

Dr. Sfurti Mann

Internal Medicine

get ultrasound abdomen, LKT, KFT, amylase, lipase done to know the cause of pain. take tab meftal forte for abdominal spasmodic pain.

FAQs

Can I stop taking Dotrasulide 40mg/100mg Tablet when my pain is relieved?

Dotrasulide 40mg/100mg Tablet is usually used for short term and can be discontinued if there is no pain. However, it should be continued if your doctor told you to do so.

Can the use of Dotrasulide 40mg/100mg Tablet cause damage to the liver?

Dotrasulide 40mg/100mg Tablet contains nimesulide. This medicine is known to cause harm to the liver especially in the doses above the recommended level. Avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. The symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes, and abnormal liver enzymes.

Can I take a higher than the recommended dose of Dotrasulide 40mg/100mg Tablet?

No, taking a higher than the recommended dose of Dotrasulide 40mg/100mg Tablet can lead to increased chances of side effects. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the instructions for the storage and disposal of Dotrasulide 40mg/100mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop taking Dotrasulide 40mg/100mg Tablet when my pain is relieved?

Dotrasulide 40mg/100mg Tablet is usually used for short term and can be discontinued if there is no pain. However, it should be continued if your doctor told you to do so.

Can the use of Dotrasulide 40mg/100mg Tablet cause damage to the liver?

Can I take a higher than the recommended dose of Dotrasulide 40mg/100mg Tablet?

What are the instructions for the storage and disposal of Dotrasulide 40mg/100mg Tablet?

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

PubChem. Drotaverine. [Accessed 15 Apr. 2019] (online) Available from:
Nimesulide. 2004]. [Accessed 15 Apr. 2019] (online) Available from:
MedIndia. Drotaverine - Indications, Dosage, Side Effects and Precautions. [Accessed 15 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 15 Apr. 2019] (online) Available from:

Marketer details

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Address: 81, Industrial Estate, Ambala Cantt 133006, Haryana.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.