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Dotmef Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 19 Jan 2026 | 01:34 AM (IST)
Dotmef Tablet is a pain-relieving medicine used for the symptomatic relief of pain associated with muscle spasms and inflammation. It is commonly prescribed for menstrual pain (dysmenorrhoea), tension-type headache, and pain caused by smooth muscle spasms of the biliary and urinary tract.
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Dotmef Tablet is currently sold out
Same composition alternative:
Almefkem-D Tablet
₹103₹159.38
Available alternative from Alkem Laboratories
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Dotmef Tablet
Dotmef Tablet
strip of 10 tablets
₹58
₹65.63
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Same composition
Almefkem-D Tablet
Almefkem-D Tablet
strip of 10 tablets
by Alkem Laboratories Ltd
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₹103
₹8.75 per tablet

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₹1200

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The content is shown in English
Dotmef Tablet image
Dotmef Tablet image
Dotmef Tablet image
Dotmef Tablet image

Product introduction

Dotmef Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your healthcare team know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects are diarrhea, nausea, vomiting, stomach pain, dry mouth, loss of appetite, feeling thirsty, and heartburn. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine, as it can worsen your dizziness.


Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Dotmef Tablet

Benefits of Dotmef Tablet

Pain relief
Dotmef Tablet provides effective relief from pain caused by muscle spasms and inflammation, making it especially useful for menstrual pain (dysmenorrhea), cramp-like abdominal pain, biliary and urinary tract spasm-related pain, and tension-type headaches. It relaxes tight smooth muscles and reduces inflammation. This helps ease sharp, cramping pain and associated discomfort.

Side effects of Dotmef Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dotmef
  • Vomiting
  • Changes in pulse rate
  • Headache
  • Skin reaction
  • Dryness in mouth
  • Dizziness
  • Nausea

How to use Dotmef Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dotmef Tablet should be taken with or after food.

How Dotmef Tablet works

Dotmef Tablet is a combination of two medicines: Drotaverine and Mefenamic Acid. Drotaverine works by relaxing smooth muscles, which helps relieve spasm-related pain, while mefenamic acid reduces inflammation and pain by lowering the production of pain-causing substances in the body. Together, they provide effective relief from cramp-like and inflammatory pain.

Quick tips

  • Consider taking Dotmef Tablet with food to prevent an upset stomach.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol while taking Dotmef Tablet, as it can cause excessive drowsiness and increase your risk of stomach problems.
  • If you get diarrhea while taking this medicine, you should stop taking it and consult your doctor.
  • Your doctor may regularly monitor your kidney and liver function if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Dotmef Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Dotmef Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Dotmef Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Dotmef Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Dotmef Tablet may cause vertigo.
Kidney

Kidney

UNSAFE
Dotmef Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

UNSAFE
Dotmef Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Yes, Dotmef Tablet is safe if prescribed by the doctor. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, diarrhoea, loss of appetite, dryness in the mouth, weakness, sleepiness, and other uncommon or rare side effects. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Dotmef Tablet is usually used for the short term and can be discontinued when your pain is relieved. However, Dotmef Tablet should be continued if your physician has advised you to do so.
Yes, the use of Dotmef Tablet can cause nausea and vomiting. Taking it with milk, food, or with antacids can prevent nausea. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Also, avoid taking fatty or fried foods along with the medicine. Talk to your doctor if you have vomiting that persists and you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine. Do not take any other medicine without consulting your doctor.
Yes, the use of Dotmef Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Avoid spicy, salty, and acidic foods (like lemons).

Fact Box

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Therapeutic Class

GASTRO INTESTINAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Siddhichemo Pharmaceuticals
Address: 1/605 krishna vatika, c.s road no - 4, Dahisar (East ), Mumbai, mobile no - 7011670201

Vendor Details

Country of origin: India
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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