



Diprovate Plus Lotion
Betamethasone (0.05% w/v)+ Zinc Sulfate (0.5% w/v)
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Diprovate Plus Lotion is a combination medicine used in the treatment of skin infections or dermatitis. It prevents the growth of microorganisms that cause the infection. It also relieves pain, irritation, and itchiness of the skin.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)
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General Information
The content is shown in English




Product introduction
Diprovate Plus Lotion is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
The most common side effects of this medicine are dryness, itchiness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.). Drink plenty of water and apply moisturizing cream or lotion to cope up with the side effects.
Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine and discuss it with your doctor. Consult the doctor before receiving any cosmetic treatment.
The most common side effects of this medicine are dryness, itchiness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.). Drink plenty of water and apply moisturizing cream or lotion to cope up with the side effects.
Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine and discuss it with your doctor. Consult the doctor before receiving any cosmetic treatment.
Uses of Diprovate Plus Lotion
Benefits of Diprovate Plus Lotion
Treatment of Dermatitis
Diprovate Plus Lotion helps manage the symptoms of dermatitis such as dry, itchy, swollen, red, and painful skin with a burning sensation. It has a soothing effect on the skin and gives relief from itching. Diprovate Plus Lotion also has antiseptic property and thus prevents any infection in the affected area. Apply Diprovate Plus Lotion to the affected area usually up to 3-4 times a day or as directed by your doctor. You may see results after 2-3 weeks however, it may vary from person to person as well as on the severity of the condition.
Diprovate Plus Lotion helps manage the symptoms of dermatitis such as dry, itchy, swollen, red, and painful skin with a burning sensation. It has a soothing effect on the skin and gives relief from itching. Diprovate Plus Lotion also has antiseptic property and thus prevents any infection in the affected area. Apply Diprovate Plus Lotion to the affected area usually up to 3-4 times a day or as directed by your doctor. You may see results after 2-3 weeks however, it may vary from person to person as well as on the severity of the condition.
Side effects of Diprovate Plus Lotion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diprovate Plus
- Application site reactions (burning, irritation, itching and redness)
How to use Diprovate Plus Lotion
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.
How Diprovate Plus Lotion works
Diprovate Plus Lotion is a combination of two medicines: Betamethasone and Zinc Sulfate. Betamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Zinc Sulfate works as an astringent and antiseptic on the skin.
All substitutes for Diprovate Plus Lotion
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Diprovate Plus Lotion helps relieve redness and itching associated with inflammatory skin conditions such as dermatitis.
- It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- Do not apply it to broken or infected areas of skin unless instructed by your doctor.
- Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get it in these areas.
- Do not use this medicine more often or for longer than advised by your doctor. Consult your doctor if your skin condition has not improved after two weeks of treatment.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Diprovate Plus Lotion during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Diprovate Plus Lotion may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Frequently asked questions
Use of Diprovate Plus Lotion is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. Avoid its use in case of any fungal infections (ringworm or athlete's foot), viral infections (herpes or chickenpox) or for treatment of acne or rosacea. Avoid its use in itchy areas which are not red and around the genitalia and anus. Consult your doctor before using it for any other condition.
Diprovate Plus Lotion should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of Diprovate Plus Lotion to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using Diprovate Plus Lotion unless it is used for treating a condition of the hands. Avoid any contact with the eyes.
No, do not stop using Diprovate Plus Lotion and complete the full course of treatment even if you feel better. Your symptoms may improve before the underlying disease is completely cured.
Do not use Diprovate Plus Lotion for longer periods of time than advised especially on the face as it may cause thinning of the skin. If it has to be applied over the eyelid, make sure it does not get into your eyes. Unless told by your doctor, do not apply a bandage or dressing to the area being treated, as this will increase absorption of the preparation and increase the risk of side-effects. This medicine should only be used by the patient, never give it to other people even if their condition appears to be the same.
The dose and duration of using Diprovate Plus Lotion should be strictly according to the doctor’s advice. This medicine when used in higher doses and for long periods can get absorbed in the blood circulation and cause adrenal suppression and Cushing's syndrome. It can cause weight gain, high blood pressure and rounding of the face. Its application can cause a change in the color of skin. Veins beneath the skin become visible due to the thinning and weakening of the skin. There could be an increased hair growth. If you experience an increased severity of your symptoms, please consult your doctor for re-evaluation.
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Keep it away from pets and children.
Fact Box
Habit Forming
No
Therapeutic Class
HORMONES
References
- Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 681-697.
- Schimmer BP, Parker KL. Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex. In: Brunton LL, Chabner BA, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. pp. 845-861.
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User feedback
Once A Day
100%
Allergic conditions
34%
Dermatitis
26%
Skin disorders
18%
Others
16%
Nutritional deficiencies
5%
Average
43%
Excellent
42%
Poor
15%
Application site reactions (burning, irritation, itching and redness)
33%
No Side Effect
33%
Contact dermatitis
17%
Acne
17%
With or without food
71%
With food
21%
Empty stomach
7%
Average
49%
Expensive
41%
Not Expensive
10%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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