Dinost 0.5mg Gel is a medicine used to induce labor in women, who are ready to deliver a full term baby. It works by softening and widening the cervix (lower end of the uterus) and helps the baby to pass through easily.

Dinost 0.5mg Gel is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals. The dose and how often you take it depends on what you are taking it for. You might be asked to lie down for at least 30 minutes after medicine application.

The most common side effects of this medicine include vomiting, diarrhea, back pain, and flushing of the skin. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a heart attack, or have asthma or have high or low blood pressure. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You may be checked for contraction timely by your doctor while on treatment with this medicine.

Uses of Dinost Vaginal gel

Induction of labour

Side effects of Dinost Vaginal gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dinost

Nausea
Diarrhea
Vomiting
Fever
Uterine tachysystole
Uterine hyperstimulation
Flushing of skin

How to use Dinost Vaginal gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying

How Dinost Vaginal gel works

Dinost 0.5mg Gel is similar to a natural substance (E2 prostaglandin) which is released in your body when labour starts. It works by opening the part of the birth canal (cervix) and causing the uterus to contract, to allow the baby through.

Safety advice

Alcohol

No interaction found/established

Pregnancy

SAFE IF PRESCRIBED

Dinost 0.5mg Gel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Dinost 0.5mg Gel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Dinost 0.5mg Gel

₹241/Vaginal gel

Medidin Gel

Medipol Pharmaceuticals India Pvt Ltd

₹242/vaginal gel

1% cheaper

Cerviprime 0.5mg Gel

Zydus Healthcare Limited

₹284.65/vaginal gel

16% costlier

Quick tips

Dinost 0.5mg Gel helps induce labour in pregnant women.
It is only used in a hospital or clinic by your doctor.
Your doctor may ask you to lie down for at least 30 minutes to keep the medication in place.
A second dose of medicine may be given if contractions are not strong enough.
You may be monitored closely after administration to make sure that the contractions do not become too strong and no distress comes to the baby.
Inform your doctor if you have heart, kidney, lung or liver disease or if you have a history of asthma.

Fact Box

Chemical Class

Prostaglandin Analog

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

PG E2 analogue

Patient concerns

I am pregnant.the doctor's date was 06.12.2016.but till now labour pain is not being occured.pls give the proper suggestions

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Go for induction of labour

Baby is correct position but no pain till now and the due date is 13- feb-2017

Dr. Suman Rao

Obstetrics and Gynaecology

Go for induction of labour if you have no pain till 15th

I am 15 weeks pregnant with bicornuate uterus have sometime bleeding if i walk or strain too much. scanning is done and got confirmation that feotus is good no issues with the baby growth. This is my second pregnancy. I just want to know whether any problem would occur as the baby grows. Pls advise.

Dr. Suman Rao

Obstetrics and Gynaecology

You can have a slightly high risk of going into preterm labour .

User feedback

What are you using Dinost Vaginal gel for?

Induction of *

100%

*Induction of labour

How much was the improvement?

Poor

62%

Excellent

24%

Average

14%

What were the side-effects while using Dinost 0.5mg Gel?

Increased ute*

50%

No Side Effec*

50%

*Increased uterine contractions, No Side Effect

How do you take Dinost Vaginal gel?

Empty stomach

100%

Please rate Dinost 0.5mg Gel on price

Average

67%

Expensive

33%

FAQs

What is Dinost 0.5mg Gel?

Dinost 0.5mg Gel works similar to Prostaglandin E2, a substance produced naturally by the women’s body. It helps in initiating the labor in women who are ready to deliver a full-term baby. It works by softening and widening the cervix.

How is it applied?

This medicine is not for self-application purpose. It is usually applied in hospital settings by a medical healthcare professional like a nurse or doctor. It is placed in the upper vagina. This medicine remains active for 6 hours.

How many doses do I need?

The dose would depend on your response to the medicine. In some patients, a single dose of this medicine usually starts labor. Sometimes, a dose may be repeated if your doctor feels that the cervix is not completely ready for the labor. In a few cases, the dose may be repeated multiple times.

What should I expect when I get this medicine?

After inserting this medicine, you and your’s baby vitals may be monitored constantly. You will be advised to lie down for at least 30 minutes. Any contractions will also be monitored. Your doctor may examine you after 6 hours or earlier in case you have strong contractions, to check for progress of labor.

What could be the possible side effects associated with it?

The side effects of Dinost 0.5mg Gel are uncommon but they can occur. A small number of women may have fever, nausea, vomiting, or diarrhea. Some women may experience a high number of uterine contractions, which may or may not stress your baby.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Schimmer BP, Parker KL. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1850.
Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 325.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 413-14.
Dinoprostone. New York, New York: Pfizer; 2017. [Accessed 03 Apr. 2019] (online) Available from:
Dinoprostone. East Kilbride, Scotland: Ferring Controlled Therapeutics Ltd. (FCT); 2017. [Accessed 14 Feb. 2019] (online) Available from:
Drugs.com. Dinoprostone. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:

Marketer details

Name: Neon Laboratories Ltd

Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Country of origin: India

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