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Diapar Tablet is a prescription medicine used in the treatment of migraine. It prevents pain signals to reach the brain to reduce pain. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 03:27 PM (IST)
₹41.2 MRP ₹45.239% off 
Gurgaon
 
 
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Diike 10mg/500mg Tablet
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Diapar Tablet
Diapar Tablet
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₹41.2
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Same composition
Diike 10mg/500mg Tablet
Diike 10mg/500mg Tablet
strip of 10 tablets
Domperidone (10mg) + Paracetamol (500mg)
by Cadila Pharmaceuticals Ltd
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₹20.7
₹1.9 per tablet

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General Information

Contains

Domperidone (10mg)+ Paracetamol (500mg)

Marketer

Navil Laboratories Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Diapar Tablet image
Diapar Tablet image

Product introduction

Diapar Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effect is dryness in mouth. This is temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Diapar Tablet

Benefits of Diapar Tablet

Treatment of Migraine
Diapar Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Diapar Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diapar
  • Dryness in mouth

How to use Diapar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diapar Tablet is to be taken on an empty stomach.

How Diapar Tablet works

Diapar Tablet is a combination of two medicines: Domperidone and Paracetamol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

All substitutes for Diapar Tablet

For information purposes only. Consult a doctor before taking any medicine.

Primol D 500mg/10mg Tablet

by Altius Life Sciences
₹3.98/tablet
3% cheaper
<h3 class=bodySemiBold>Primol D 500mg/10mg Tablet</h3>

Casdom P 10mg/500mg Tablet

by Casca Remedies Pvt Ltd
₹2.05/tablet
50% cheaper
<h3 class=bodySemiBold>Casdom P 10mg/500mg Tablet</h3>

Dominaus-P 10mg/500mg Tablet

by Minova Life Sciences Pvt Ltd
₹2.99/tablet
27% cheaper
<h3 class=bodySemiBold>Dominaus-P 10mg/500mg Tablet</h3>

Dompac 10mg/500mg Tablet

by Ester Formulations
₹1.28/tablet
69% cheaper
<h3 class=bodySemiBold>Dompac 10mg/500mg Tablet</h3>

Acedome 10mg/500mg Tablet

by Symbiosis Lab
₹1.88/tablet
54% cheaper
<h3 class=bodySemiBold>Acedome 10mg/500mg Tablet</h3>

Quick tips

  • Diapar Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you are taking any pain relief medicine.
  • Diapar Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.
  • Diapar Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you are taking any pain relief medicine.
  • Diapar Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Diapar Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Diapar Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Diapar Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Diapar Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Diapar Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Diapar Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Diapar Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Diapar Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
No, taking a higher than the recommended dose of Diapar Tablet can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
No, there is no report of any patient getting addicted to Diapar Tablet.
Yes, Diapar Tablet can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 15 Apr. 2019] (online) Available from:
  2. ScienceDirect. Domperidone. [Accessed 15 Apr. 2019] (online) Available from:
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User feedback

Once A Day
78%
Thrice A Day
11%
Twice A Day
11%
Migraine
40%
Headache
20%
Others
20%
Pain relief
20%
Average
100%
No Side Effect
100%
Empty stomach
100%
Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Navil Laboratories Pvt Ltd
Address: Rose Cliff Bunglow, Next To Fatima Devi High School, Manchhubhai Road, Near Malad Subway, Malad (East), Mumbai - 400097, Maharashtra, India

Vendor Details

Country of origin: India

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