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Primol D 500mg/10mg Tablet

Domperidone (10mg)+ Paracetamol (500mg)

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Primol D 500mg/10mg Tablet is a prescription medicine used in the treatment of migraine. It prevents pain signals to reach the brain to reduce pain. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 10 Sep 2026 | 01:04 AM (IST)

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10 tablets

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Gurgaon

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General Information

Contains

Domperidone (10mg)+ Paracetamol (500mg)

Marketer

Altius Life Sciences

Storage

Store below 30°C

The content is shown in English

Product introduction

Primol D 500mg/10mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effect is dryness in mouth. This is temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Primol D Tablet

Treatment of Migraine

Benefits of Primol D Tablet

Treatment of Migraine
Primol D 500mg/10mg Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Primol D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Primol D

Limited data available

How to use Primol D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Primol D 500mg/10mg Tablet is to be taken on an empty stomach.

How Primol D Tablet works

Primol D 500mg/10mg Tablet is a combination of two medicines: Domperidone and Paracetamol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

All substitutes for Primol D 500mg/10mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Primol D 500mg/10mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Inform your doctor if you are taking any pain relief medicine.
Primol D 500mg/10mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
Some tips that may help avoid a migraine attack:
1. Have your meals at the same time every day.
2. Avoid bright lights and extreme temperatures.
3. Avoid loud music and noisy places.
4. Avoid chocolates, cheese, processed food, alcohol, and smoking.
5. Get sufficient sleep and avoid stress.
Primol D 500mg/10mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Inform your doctor if you are taking any pain relief medicine.
Primol D 500mg/10mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
Some tips that may help avoid a migraine attack:
1. Have your meals at the same time every day.
2. Avoid bright lights and extreme temperatures.
3. Avoid loud music and noisy places.
4. Avoid chocolates, cheese, processed food, alcohol, and smoking.
5. Get sufficient sleep and avoid stress.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Primol D 500mg/10mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Primol D 500mg/10mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Primol D 500mg/10mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Primol D 500mg/10mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Primol D 500mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Primol D 500mg/10mg Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Primol D 500mg/10mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

What is Primol D 500mg/10mg Tablet?

Primol D 500mg/10mg Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Primol D 500mg/10mg Tablet can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Can I get addicted to Primol D 500mg/10mg Tablet?

No, there is no report of any patient getting addicted to Primol D 500mg/10mg Tablet.

Can the use of Primol D 500mg/10mg Tablet cause damage to liver?

Yes, Primol D 500mg/10mg Tablet can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.

What is the recommended storage condition for the Primol D 500mg/10mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Altius Life Sciences
Address: Booth No. 184, Sec-16, Panchkula, Haryana 134102

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Primol D 500mg/10mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Home

Neuro Cns

Anti Migraine Preparations

Primol D 500mg/10mg Tablet

Primol D 500mg/10mg Tablet

Payment, Returns & Expiry

Cash on delivery available

7 day free return

Product expires after Dec, 2026

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Primol D Tablet

Benefits of Primol D Tablet

Side effects of Primol D Tablet

How to use Primol D Tablet

How Primol D Tablet works

All substitutes for Primol D 500mg/10mg Tablet

Anadom 10mg/500mg Tablet

Casdom P 10mg/500mg Tablet

Acedome 10mg/500mg Tablet

Betadom P 10mg/500mg Tablet

Pyril-D Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Primol D 500mg/10mg Tablet?

Can I take a higher than the recommended dose of this medicine?

Can I get addicted to Primol D 500mg/10mg Tablet?

Can the use of Primol D 500mg/10mg Tablet cause damage to liver?

What is the recommended storage condition for the Primol D 500mg/10mg Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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