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18 Feb 2020 | 05:25 PM (IST)
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Depaxil CR Plus 25 Tablet

Prescription Required
Storage
Store at room temperature (10-30°C)

Introduction

Depaxil CR Plus 25 Tablet is a prescription medicine used to treat depression. It is a combination medicine which works by increasing the level of chemical messengers in the brain that improves mood. It also calms the brain by decreasing the abnormal and excessive activity of the nerve cells.

Depaxil CR Plus 25 Tablet can be taken with or without food. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. Try to never skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may result in withdrawal symptoms.

Some common side effects of this medicine include nausea, vomiting, confusion, memory impairment, low sexual desire, confusion, and delayed ejaculation. It may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you.  It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Depaxil Plus Tablet ER

Side effects of Depaxil Plus Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depaxil Plus

  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Depaxil Plus Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depaxil CR Plus 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Depaxil Plus Tablet ER works

Depaxil CR Plus 25 Tablet is a combination of two medicines: Paroxetine and Clonazepam which has mood-enhancing and anxiety-lowering effects. Paroxetine is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Depaxil CR Plus 25 Tablet.
Pregnancy
UNSAFE
Depaxil CR Plus 25 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
CONSULT YOUR DOCTOR
Depaxil CR Plus 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Depaxil CR Plus 25 Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Depaxil CR Plus 25 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Depaxil CR Plus 25 Tablet may not be needed in these patients. Please consult your doctor.
Use of Depaxil CR Plus 25 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
Depaxil CR Plus 25 Tablet should be used with caution in patients with liver disease. Dose adjustment of Depaxil CR Plus 25 Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Depaxil CR Plus 25 Tablet
₹17.3/Tablet ER
Panazep 25 Tablet ER
Sun Pharmaceutical Industries Ltd
₹18.2/Tablet ER
5% costlier

Fact Box

Habit Forming
Yes

Patient Concerns

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He was diagnose one of nerve is brain has shrinked causing body imbalance headache taking 1.depaxil cr 25 mg 2.Alp sr .5 nd 3. Betacap side effect observed are overactive more nd repetitive talking what to do now
Dr. Vikas Sharma
Neurology
Pt needs to seen yo gib opinion
I had recently undergone left humerus plating surgery and i was told to take setfrac plus tablet The problem is setfrac plus tablet is not available in my town so can u please sugeat the substitute tablet to setfrac plus?????
Dr. Rohit Chakor
Orthopaedics
You see the content of the tablet and ask for it
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Do you have any questions related to Depaxil CR Plus 25 Tablet ?

User Feedback


FAQs

Q. Are there any important warnings associated with the use of Depaxil CR Plus 25 Tablet?

Depaxil CR Plus 25 Tablet may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Depaxil CR Plus 25 Tablet when my symptoms are relieved?

No, you should continue taking Depaxil CR Plus 25 Tablet even if you feel well. If you stop Depaxil CR Plus 25 Tablet suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Depaxil CR Plus 25 Tablet?

There are reports that suggest that the use of Depaxil CR Plus 25 Tablet can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Depaxil CR Plus 25 Tablet cause sleepiness?

Yes, Depaxil CR Plus 25 Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Depaxil CR Plus 25 Tablet affect my sex life?

The use of Depaxil CR Plus 25 Tablet can affect the sexual life of both men and women. Different sexual problems can occur due to Depaxil CR Plus 25 Tablet like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Depaxil CR Plus 25 Tablet?

No, do not drink alcohol while taking Depaxil CR Plus 25 Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Depaxil CR Plus 25 Tablet.

Q. How long does Depaxil CR Plus 25 Tablet take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Depaxil CR Plus 25 Tablet, although some people may start to feel better sooner. When taking Depaxil CR Plus 25 Tablet, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Depaxil CR Plus 25 Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Paroxetine. Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
NOT FOR SALE
We do not facilitate sale of this product at present

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