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Last updated on:
15 Jan 2019 | 11:31 AM (IST)
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Depaxil CR Plus 25 Tablet


Uses of Depaxil Plus Tablet ER

Depaxil CR Plus 25 Tablet is used in the treatment of depression.

Depaxil Plus Tablet ER side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairement
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Depaxil Plus Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depaxil CR Plus 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Depaxil Plus Tablet ER works

Depaxil CR Plus 25 Tablet is a combination of two medicines: Paroxetine and Clonazepam which has mood-enhancing and anxiety-lowering effects. Paroxetine is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Depaxil Plus Tablet ER related warnings

Depaxil CR Plus 25 Tablet may cause excessive drowsiness and calmness with alcohol.
Depaxil CR Plus 25 Tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
Depaxil CR Plus 25 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Depaxil CR Plus 25 Tablet may cause side effects which could affect your ability to drive.
Depaxil CR Plus 25 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Depaxil CR Plus 25 Tablet may not be needed in these patients. Please consult your doctor.
Use of Depaxil CR Plus 25 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Depaxil CR Plus 25 Tablet should be used with caution in patients with liver disease. Dose adjustment of Depaxil CR Plus 25 Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Depaxil CR Plus 25 Tablet
₹17.3/Tablet ER
Panazep 25 Tablet ER
Sun Pharmaceutical Industries Ltd
₹17.5/Tablet ER
1% costlier

Patient Concerns

Questions Related to Depaxil Plus

sir, my self im very depressing while comparing me to others& i dont talk to much bcoz i feel im not in level to talk with them & feel me about myself everyday about my negetativity.this type thinking stressess me very much how can i come from this type of stress?? i feel this is b.coz my weight & height at the age of 21 im right sir??
Dr. Jyoti Kapoor Madan
If you let your confidence down, you will develop helplessness ehic leads to depression. Instead of worrying about your weight, take action. Seek professional help. If you feel unmotivated, meet a psychiatrist, its neither too early nor too late for professional advice.
Sir i m suffering from mindly disturbance last 8 days because i have fail in love . Now i dont get to sleep. Only 2-3 hrs sleeping please help me. Im in more depression
Dr. Mehtab Baig
Think one mantra ,,,,,duniya jaye bhad me ,,,,, if u don't you takes always on medicine plz ignore all your memories with your ex And deleted
Do you have any questions related to Depaxil CR Plus 25 Tablet?


Q. Are there any important warnings associated with the use of Depaxil Plus?

Depaxil Plus may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Depaxil Plus when my symptoms are relieved?

No, you should continue taking Depaxil Plus even if you feel well. If you stop Depaxil Plus suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Depaxil Plus?

There are reports that suggest that the use of Depaxil Plus can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Depaxil Plus cause sleepiness?

Yes, Depaxil Plus can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Depaxil Plus affect my sex life?

The use of Depaxil Plus can affect the sexual life of both men and women. Different sexual problems can occur due to Depaxil Plus like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Depaxil Plus?

No, do not drink alcohol while taking Depaxil Plus. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Depaxil Plus.

Q. How long does Depaxil Plus take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Depaxil Plus, although some people may start to feel better sooner. When taking Depaxil Plus, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Depaxil Plus?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Ayurvedic Ingredients

The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
We do not facilitate sale of this product at present