Depart Cold Tablet

Phenylephrine (5mg)+ Dexchlorpheniramine (2mg)+ Paracetamol (325mg)+ Caffeine (16mg)

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Depart Cold Tablet is a medicine used to treat common cold symptoms. It provides relief from symptoms like runny nose, sneezing, watery eyes, and nasal congestion. It also blocks the release of certain chemical messengers that cause pain and inflammation and relieves aches and fever associated with cold.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Jul 2026 | 01:07 AM (IST)

₹49.3 MRP ₹55.3111% off

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General Information

Contains

Phenylephrine (5mg)+ Dexchlorpheniramine (2mg)+ Paracetamol (325mg)+ Caffeine (16mg)

Marketer

Winbaxy Laboratory

Storage

Store below 30°C

The content is shown in English

Product introduction

Depart Cold Tablet may be taken with or without food. Take it regularly and at the same time each day to get maximum benefits from it. Do not take this medicine more than the recommended dose. An overdose may have harmful effects on the body. Prolong use of this medicine may harm your health, do not take it more than the prescribed duration unless your doctor advised you to do so.

It may cause side effects like nausea, vomiting, and upset stomach in some patients. Let your doctor know if any of these side effects bother you. Inform your doctor immediately if any rash or allergic reaction is observed while taking this medicine. They may be able to suggest ways to reduce or treat the side effects.

Before taking this medicine, let your doctor know if you have any other medical conditions. Let your doctor also know about all the other medicines you are taking. To make sure it is safe for you, tell your doctor if you are pregnant, breastfeeding.

Uses of Depart Cold Tablet

Treatment of Common cold

Benefits of Depart Cold Tablet

Treatment of Common cold
Depart Cold Tablet is a combination of medicines that effectively relieves symptoms of common cold such as runny nose, watery eyes, sneezing, congestion, or stuffiness. It narrows the blood vessels in the nose and provides rapid relief from congestion. Depart Cold Tablet also does not cause much sleepiness due to the presence of Caffeine in it. As a result, you can do your daily activities more easily. Depart Cold Tablet is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.

Side effects of Depart Cold Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depart Cold

Nausea
Vomiting
Upset stomach

How to use Depart Cold Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depart Cold Tablet may be taken with or without food.

How Depart Cold Tablet works

Phenylephrine is a nasal decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Dexchlorpheniramine is an antihistamine medication. It blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Caffeine is a stimulant which works by blocking the action of certain natural substances (adenosine and phosphodiesterase).

Quick tips

Depart Cold Tablet is prescribed to get relief from symptoms of common cold.
Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
Call your doctor if your symptoms have not improved within seven days of treatment.
Inform your doctor if you are taking any other medications for cold.
Along with taking Depart Cold Tablet do the following simple tips at home to get relief:
1. Steam inhalation.
2. Gargling with warm saltwater.
3. Apply vapor rubs on chest, back if needed. Take enough rest.
4. Take warm food and fluid only. Ensure adequate fluid intake.
5. Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcases, etc.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Depart Cold Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Depart Cold Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Depart Cold Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Depart Cold Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Depart Cold Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Depart Cold Tablet is unsafe to use in patients with liver disease and should be avoided.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

References

Kiran MD, Waghambare PD, Pawaskar L, et al. Fixed-dose Combination Therapy of Paracetamol, Phenylephrine, and Chlorpheniramine Maleate for the Symptomatic Treatment of Common Cold in Indian Adults. J Assoc Physicians India. 2024;72(11):45-48. [Accessed 29 Dec. 2025]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Winbaxy Laboratory
Address: WINBAXY LABORATORY, FF-25, THE VALENCIYA, B/H PRIYA CINEMA VADODARA - 390021, GUJ- IND Vadodara, Gujarat 390021 India

Vendor Details

Country of origin: India

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Depart Cold Tablet

Depart Cold Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Depart Cold Tablet

Benefits of Depart Cold Tablet

Side effects of Depart Cold Tablet

How to use Depart Cold Tablet

How Depart Cold Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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