Daparyl-VM 500 Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Daparyl-VM 500 Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in the proper utilization of insulin, thereby lowering the blood sugar level.

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General Information

Contains

Dapagliflozin (10mg)+ Metformin (500mg)+ Vildagliptin (100mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Daparyl-VM 500 Tablet is best taken with food. The dose will be decided by your doctor, and don’t stop taking it unless the doctor advises otherwise. If stopped abruptly, your blood sugar levels may increase and can put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by the doctor.

The most common side effects of this medicine include vaginal yeast infection, nasopharyngitis, urinary tract infection, diarrhea, headache, nausea, and vomiting. Drinking plenty of fluids while using it will help prevent dehydration. Maintaining good hygiene can help prevent fungal infections in the genital area.

Before taking Daparyl-VM 500 Tablet, inform your doctor if you have any kidney or liver problems, a urinary tract infection, or you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly.

Uses of Daparyl-VM Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Daparyl-VM Tablet

Treatment of Type 2 diabetes mellitus
Daparyl-VM 500 Tablet is a medicine that helps control high blood glucose (sugar) levels. It helps remove extra glucose from your body through urine. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the glucose level, the risk of any serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs, is reduced. This medicine also reduces the risk of dying from cardiovascular disease if you have type 2 diabetes and cardiovascular disease.

Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. Keep using this drug for as long as it is prescribed because it is protecting your future health.

Side effects of Daparyl-VM Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Daparyl-VM

Vaginal yeast infection
Nasopharyngitis (inflammation of the throat and nasal passages)
Urinary tract infection
Diarrhea
Headache
Nausea
Vomiting

How to use Daparyl-VM Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Daparyl-VM 500 Tablet should be taken with or after food.

How Daparyl-VM Tablet works

Daparyl-VM 500 Tablet is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Vildagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood. Metformin decreases the amount of glucose absorbed from your food and the amount of glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood.

All substitutes for Daparyl-VM 500 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor will monitor your blood sugar levels regularly when you are taking Daparyl-VM 500 Tablet.
Hypoglycemia (low blood sugar level) may occur when Daparyl-VM 500 Tablet is taken along with other antidiabetic medicines, alcohol, or on delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief.
If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are the signs of too much sugar in your blood and your dose may need adjusting.
Lifestyle changes like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you usually drink may help this medication work better.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Daparyl-VM 500 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Daparyl-VM 500 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Daparyl-VM 500 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Daparyl-VM 500 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Daparyl-VM 500 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Daparyl-VM 500 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Is Daparyl-VM 500 Tablet safe for the kidneys?

Daparyl-VM 500 Tablet does not cause kidney damage. The kidneys process and clear the drug out of your system via urine. However, if your kidneys are not functioning properly, this medicine can lead to a condition called lactic acidosis. Its symptoms include tiredness, weakness, muscle pain, sleepiness, abdominal pain, and breathing problems. Seek immediate medical advice in case you notice any such symptoms.

Can Daparyl-VM 500 Tablet cause dizziness?

Yes, Daparyl-VM 500 Tablet can lower your blood sugar level and make you feel dizzy if taken with other antidiabetic medicines. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling. Also, monitor your blood sugar level at regular intervals.

Can this medicine be used to treat type 1 diabetes?

This medication does not treat type 1 diabetes or diabetic ketoacidosis (increased ketones in the blood or urine).

Can Daparyl-VM 500 Tablet cause pancreatitis?

There have been reports of acute pancreatitis due to Daparyl-VM 500 Tablet. Patients are prompted to discontinue this medicine and contact their doctor if there is persistent severe abdominal pain, sometimes radiating to the back.

What should you not eat while taking Daparyl-VM 500 Tablet?

It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar levels.

Is Daparyl-VM 500 Tablet tablet safe to use?

Yes, Daparyl-VM 500 Tablet tablet is safe when used as directed by the doctor; however, it may show some side effects. For best results, this medicine should be used in the correct dose and at the same time each day.

Can I stop taking Daparyl-VM 500 Tablet tablet?

No, do not stop taking Daparyl-VM 500 Tablet tablets without talking to your doctor first. Sudden discontinuation of this medicine may worsen your diabetes. Inform your doctor if the symptoms bother you, or if no considerable improvement is seen in your condition. The doctor may suggest some other medicine that could be more effective in treating your diabetes.

Can people with diabetes have proteins?

Yes, people with diabetes must include protein along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet. It is often recommended to consume about 2-3 teaspoons of proteins in the evening snacks to avert the chances of hypoglycemia.

Are artificial sweeteners good for people with diabetes?

No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.

Can diabetes cause kidney failure?

Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy, as this condition is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to the kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.

Can diabetes be cured?

Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. Although it cannot be cured permanently, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Dapagliflozin and metformin HCl [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2017. [Accessed 10 Mar. 2023]. (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Daparyl-VM 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Daparyl-VM 500 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Daparyl-VM Tablet

Benefits of Daparyl-VM Tablet

Side effects of Daparyl-VM Tablet

How to use Daparyl-VM Tablet

How Daparyl-VM Tablet works

All substitutes for Daparyl-VM 500 Tablet

Jalra Trio Tablet

VILDApride DM 10mg/500mg/100mg Tablet

Zavamet DP 10mg/500mg/100mg Tablet

Gliptagreat DM 10mg/500mg/100mg Tablet

Vylda DM 10mg/500mg/100mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Daparyl-VM 500 Tablet safe for the kidneys?

Can Daparyl-VM 500 Tablet cause dizziness?

Can this medicine be used to treat type 1 diabetes?

Can Daparyl-VM 500 Tablet cause pancreatitis?

What should you not eat while taking Daparyl-VM 500 Tablet?

Is Daparyl-VM 500 Tablet tablet safe to use?

Can I stop taking Daparyl-VM 500 Tablet tablet?

Can people with diabetes have proteins?

Are artificial sweeteners good for people with diabetes?

Can diabetes cause kidney failure?

Can diabetes be cured?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests