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Coxwin 3 Tablet

Prescription Required

Overview

Introduction

Coxwin 3 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Coxwin 3 Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Coxwin 3 Tablet

Side effects of Coxwin 3 Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Coxwin 3

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Increased liver enzymes
  • Jaundice
  • Visual impairment
  • Increased uric acid level in blood
  • Gout
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Coxwin 3 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coxwin 3 Tablet is to be taken empty stomach.
Avoid Coxwin 3 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Coxwin 3 Tablet works

Coxwin 3 Tablet is a combination of three medicines: Rifampicin, isoniazid and ethambutol, which treats tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.

Safety Advice

Alcohol
UNSAFE
Consuming alcohol while taking Coxwin 3 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Coxwin 3 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Coxwin 3 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Coxwin 3 Tablet may cause side effects which could affect your ability to drive.
Coxwin 3 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Coxwin 3 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Coxwin 3 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Coxwin 3 Tablet should be used with caution in patients with liver disease. Dose adjustment of Coxwin 3 Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Coxwin 3 Tablet
₹3.66/Tablet
Trac 3 450 mg/300 mg/800 mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.82/Tablet
4% costlier
Mycocox E 450 mg/300 mg/800 mg Tablet
Cadila Pharmaceuticals Ltd
₹8.91/Tablet
144% costlier
Monto 3 Tablet
Shreya Life Sciences Pvt Ltd
₹10.01/Tablet
174% costlier
₹13.94/Tablet
281% costlier
Rhe-FD Tablet
Macleods Pharmaceuticals Pvt Ltd
₹15.28/Tablet
318% costlier

Quick Tips

  • It is best to take the medicine on an empty stomach one hour before or two hours after meals.
  • Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the infection harder to treat.
  • It can make birth control pills less effective so ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).
  • It can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. 

Fact Box

Habit Forming
No

Patient Concerns

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My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Do you have any questions related to Coxwin 3 Tablet ?

User Feedback


FAQs

Q. Which is the best time to take Coxwin 3?

Take Coxwin 3 exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Q. Can the use of Coxwin 3 make birth control pills ineffective?

Yes, Coxwin 3 can make birth control pills less effective. Ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Q. Is tuberculosis a curable disease?

Yes, tuberculosis (TB) is a curable disease and can be cured with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side effects.

Q. What are the instructions for the storage and disposal of Coxwin 3?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Coxwin 3 cause discoloration of the urine?

Yes, Coxwin 3 contains rifampicin which can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).

Q. Can I discontinue Coxwin 3 if I feel well?

No, do not discontinue Coxwin 3. Take the proper course of the drug that has been prescribed to you even if you begin to feel better. If you stop taking Coxwin 3, your infection may become worse and difficult to treat. It may even result in drug-resistant TB i.e. drugs you were taking may no longer work for Tuberculosis.

Q. Can Coxwin 3 cause visual impairment?

Coxwin 3 contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 10 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Marc Laboratories Limited, Plot No. 112, HP HIDC, Baddi, Solan-173205, Himachal Pradesh, India
Country of Origin: India
NOT FOR SALE
We do not facilitate sale of this product at present

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