Side Effects of Coxwin 3 are Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Increased liver enzymes, Jaundice, Visual impairment, Increased uric acid level in blood, Gout, Peripheral neuropathy (tingling and numbness of feet and hand).
How to use Coxwin 3 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coxwin 3 Tablet is to be taken empty stomach. Avoid Coxwin 3 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Coxwin 3 Tablet is a combination of three medicines: Rifampicin, isoniazid and ethambutol which treat tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.
In Depth Information on Coxwin 3 Tablet
Coxwin 3 Tablet related warnings
Special precautions for Coxwin 3 Tablet
Coxwin 3 Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
Coxwin 3 Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Coxwin 3 Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well. Coxwin 3 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Coxwin 3 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Coxwin 3 Tablet may be needed. Please consult your doctor. Kidney function tests are advisable before the start of this medicine.
Coxwin 3 Tablet should be used with caution in patients with liver disease. Dose adjustment of Coxwin 3 Tablet may be needed. Please consult your doctor.
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Take the Coxwin 3 exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
Q. Can the use of Coxwin 3 make birth control pills ineffective?
Yes, Coxwin 3 can make birth control pills less effective. Ask the doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Coxwin 3.
Q. Is tuberculosis a curable disease?
Yes, tuberculosis (TB) is a curable disease and usually with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side-effects.
Q. What are the instructions for the storage and disposal of Coxwin 3?
Keep this medicine in the packet or container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Q. Can the use of Coxwin 3 cause discoloration of the urine?
Yes, Coxwin 3 contain Rifampicin. It causes temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown colour). This side effect is usually not harmful. However, discolouration of urine can be a sign of liver damage. Call your doctor if you have discolouration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).
Q. Can I discontinue Coxwin 3 if I feel well?
No, do not discontinue Coxwin 3.Take the proper course of a drug that has been prescribed for you even if you begin to feel better. If you stop taking Coxwin 3 then your infection may become worse, may become difficult to treat and it may result in drug-resistant TB i.e drugs you were taking may no longer work for Tuberculosis.
Q. Can Coxwin 3 cause visual impairment?
Coxwin 3 contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.