Author Details
Written By
PGDHHM, BDS
Reviewed By
MBA, MBBS
Last updated
22 Mar 2024 | 03:25 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Comtripsy 6.14mg/15mg Tablet

Prescription Required

Product introduction

Comtripsy 6.14mg/15mg Tablet is a combination of two medicines that treat cancer of the colon and rectum that has spread to other parts of the body (metastasized). It works by stopping or slowing down the growth of cancer cells.

Comtripsy 6.14mg/15mg Tablet should be taken with food, but try to have it at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia, neutropenia, fatigue, nausea, thrombocytopenia, decreased appetite, diarrhea, vomiting, and fever. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Comtripsy Tablet

Benefits of Comtripsy Tablet

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Comtripsy 6.14mg/15mg Tablet treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Comtripsy Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comtripsy

  • Anemia (low number of red blood cells)
  • Decreased white blood cell count (neutrophils)
  • Fatigue
  • Nausea
  • Low blood platelets
  • Decreased appetite
  • Diarrhea
  • Fever
  • Vomiting

How to use Comtripsy Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comtripsy 6.14mg/15mg Tablet is to be taken with food.

How Comtripsy Tablet works

Comtripsy 6.14mg/15mg Tablet is a combination of two anticancer medications. Trifluridine suppresses DNA synthesis and stops the growth of cancer cells. Tipiracil slows down the degradation of trifluridine in the body.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Comtripsy 6.14mg/15mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Comtripsy 6.14mg/15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Comtripsy 6.14mg/15mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
CONSULT YOUR DOCTOR
It is not known whether Comtripsy 6.14mg/15mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Comtripsy 6.14mg/15mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Comtripsy 6.14mg/15mg Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Comtripsy 6.14mg/15mg Tablet is safe to use in patients with liver disease. No dose adjustment of Comtripsy 6.14mg/15mg Tablet is recommended.

What if you forget to take Comtripsy Tablet?

If you miss a dose of Comtripsy 6.14mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Avoid the use of antacids within two hours of taking this medicine.
  • Drink plenty of water every 24 hours after the start of the treatment.
  • You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
  • To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Eat foods that may help reduce diarrhea and take adequate rest.
  • Use contraceptives, and do not conceive a child (get pregnant) while taking Comtripsy 6.14mg/15mg Tablet. Barrier methods of contraception, such as condoms should be used during therapy and for 6 months after treatment.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient concerns

arrow
Is ulcers curable G2 stage of cancer in rectum area
Dr.
Gastroenterology
Needs evaluation Please meet a Gastro surgeon
My dad is suffering from colon cancer How to get rid of it
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Surgery is main stay of treatment, which should be followed by chemotherapy.
arrow

FAQs

Q. Can Comtripsy 6.14mg/15mg Tablet be taken during pregnancy?

This treatment may harm a baby developing in the womb. It is important not to conceive or father a child while you are on treatment with Comtripsy 6.14mg/15mg Tablet and for at least 6 months after its final dose. Talk to your doctor about effective contraception before starting the treatment.

Q. Can I breastfeed while taking Comtripsy 6.14mg/15mg Tablet?

No, it is advisable to avoid breastfeeding during the treatment with Comtripsy 6.14mg/15mg Tablet and for 1 day following its final dose.

Q. How to get relief from diarrhea while on treatment with Comtripsy 6.14mg/15mg Tablet?

Food items with soluble fiber can help relieve diarrhea as they absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid it. You can also have soups and juices frequently to hydrate yourself.

Q. Should I avoid any food and drinks while taking Comtripsy 6.14mg/15mg Tablet?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydratation, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.

Q. How will you know that Comtripsy 6.14mg/15mg Tablet is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

Q. What precautions should I take to reduce the chances of getting infected during the treatment with Comtripsy 6.14mg/15mg Tablet?

Since Comtripsy 6.14mg/15mg Tablet lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection. In order to prevent this, avoid people who have infections. Check with your doctor immediately if you think you may have been infected, or if you get a fever, chills, or cough.

Q. Why am I experiencing bleeding from my gums after brushing my teeth?

You may experience bleeding from gums due to a drop in the number of platelets (blood cells) in your blood. These blood cells help the blood clot when we bruise ourselves.

Q. How to cope with tiredness and weakness after starting the treatment?

Various things can help you reduce tiredness and cope with it, for example, gentle exercise. However, always consult your doctor before doing any kind of exercise.
Related lab tests

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Trifluridine and Tipiracil [Prescribing Information]. Princeton, NJ: Taiho Oncology, Inc.; 2019. [Accessed 25th Nov. 2022] (online) Available from:External Link
  2. Trifluridine and Tipiracil [Summary of Product Characteristics]. Gidy, France: Les Laboratoires Servier Industrie; 2016. [Accessed 25th Nov. 2022] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

3636
Inclusive of all taxes
MRP3750  3% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.