Comcapsy 400mg/20mg Tablet

Capecitabine (400mg)+ Cyclophosphamide (20mg)

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Comcapsy 400mg/20mg Tablet is used in the treatment of breast cancer. It may also be used to treat other conditions, as determined by the doctor. It is used alone or in combination with other medications as a part of chemotherapy.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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Comcapsy 400mg/20mg Tablet

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General Information

Contains

Capecitabine (400mg)+ Cyclophosphamide (20mg)

Marketer

Intas Pharmaceuticals Ltd

The content is shown in English

Product introduction

Comcapsy 400mg/20mg Tablet should be taken with food or within 30 minutes of eating. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or more than the recommended dose can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless the doctor tells you to.

The most common side effects of this medicine include hand-foot syndrome, vomiting, and asthenia. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and heart, liver, and uric acid levels.

Before taking Comcapsy 400mg/20mg Tablet, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections, as many other medicines can affect or be affected by this medicine. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment is important to avoid pregnancy.

Uses of Comcapsy Tablet

Treatment of Breast cancer

Benefits of Comcapsy Tablet

Treatment of Breast cancer
Comcapsy 400mg/20mg Tablet helps treat breast cancer, and it may be used alone or in combination with other medicines or treatment modalities, like chemotherapy. It relieves the symptoms of breast cancer, such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breasts. It kills or stops the growth of cancer cells and also prevents their multiplication. Discuss with your doctor if any of the side effects bother you.

Side effects of Comcapsy Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comcapsy

Hand-foot syndrome
Vomiting
Weakness

How to use Comcapsy Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comcapsy 400mg/20mg Tablet may be taken with or without food.

How Comcapsy Tablet works

Comcapsy 400mg/20mg Tablet is a combination of two anticancer medicines. Capecitabine interferes with the production of DNA. It stops cell growth and multiplication, resulting in the slowing or stopping of cancer growth. Cyclophosphamide damages the DNA of cancer cells and prevents their growth. Cancer cells divide faster and with less error-correcting than normal cells, making the cancer cells more prone to this damage.

Quick tips

Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Comcapsy 400mg/20mg Tablet.
Inform your doctor if you are pregnant or breastfeeding before taking this medicine.
You may be at risk of infection; hence, try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your healthcare provider.
Hand-foot-mouth syndrome is one of the most common side effects of this medicine. You may experience a skin rash, swelling, redness, pain, and/or peeling of the skin on the palms of hands and soles of feet.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Use contraceptives, and do not conceive a child (get pregnant) while taking Comcapsy 400mg/20mg Tablet. Barrier methods of contraception, such as condoms, are recommended.
Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Comcapsy 400mg/20mg Tablet.

Pregnancy

UNSAFE

Comcapsy 400mg/20mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Comcapsy 400mg/20mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Comcapsy 400mg/20mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Comcapsy 400mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Comcapsy 400mg/20mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What tests will be prescribed before starting treatment with Comcapsy 400mg/20mg Tablet?

You will be advised to get blood tests done before and during your treatment to check the level of blood cells. You might also be prescribed tests to assess how well your liver and kidneys are working.

I am experiencing nausea and extreme tiredness. Is this due to Comcapsy 400mg/20mg Tablet?

Nausea and fatigue or tiredness are some of the common side effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

Should I avoid any food and drinks while taking Comcapsy 400mg/20mg Tablet?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydration, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.

I have noticed some changes in my skin after taking Comcapsy 400mg/20mg Tablet? What should I do?

Use a moisturizer to get relief from rashes and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can worsen it. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

Fact Box

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Comcapsy 400mg/20mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Comcapsy Tablet

Benefits of Comcapsy Tablet

Side effects of Comcapsy Tablet

How to use Comcapsy Tablet

How Comcapsy Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What tests will be prescribed before starting treatment with Comcapsy 400mg/20mg Tablet?

I am experiencing nausea and extreme tiredness. Is this due to Comcapsy 400mg/20mg Tablet?

Should I avoid any food and drinks while taking Comcapsy 400mg/20mg Tablet?

I have noticed some changes in my skin after taking Comcapsy 400mg/20mg Tablet? What should I do?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests