Combither Forte 80 mg/480 mg Tablet is used for the treatment of malaria in both children and adults. It contains two medicines both of which belong to a group of medicines called antimalarials. However, it is not used to prevent malaria or to treat severe/complicated malaria (when the brain, lungs, or kidneys are affected).

Combither Forte 80 mg/480 mg Tablet works by killing the malaria-causing parasites thereby preventing further spread of the infection. It should be taken with food as this will help your body better absorb the medicine. Take it in the dose and duration advised by your doctor. Do not take more than the recommended dose, as this may have harmful effects on your body. Complete the full course of treatment to make sure the infection is treated completely.

Headache, loss of appetite, weakness, joint pain, or muscle pain are some of the common side effects associated with this medicine. You may also feel dizzy after taking this medicine. Inform your doctor if these persist or worsen.

Before taking this medicine, you should tell your doctor about all the medicines that you may be taking for any other health conditions. Pregnant or breastfeeding women should not take this medicine unless prescribed by the doctor, as it may be harmful effects on the developing baby.

Uses of Combither Forte Tablet

Treatment of Malaria

Benefits of Combither Forte Tablet

In Treatment of Malaria

Malaria is an infection that is transmitted by mosquito bites. Combither Forte 80 mg/480 mg Tablet effectively treats malaria by killing the malarial parasites. However, it should not be used to prevent malaria and should be taken only when prescribed by a doctor. This medicine makes you feel better within a few days of treatment. But, if you have fever, chills, muscle pain, or headache soon after you finish your treatment, this could be a sign that you still are infected with malaria. Consult your doctor immediately if you notice any such symptoms.

Refrain from taking any other medicines or antacids along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Combither Forte Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combither Forte

Headache
Loss of appetite
Dizziness
Weakness
Joint pain
Muscle pain

How to use Combither Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combither Forte 80 mg/480 mg Tablet is to be taken with food.

How Combither Forte Tablet works

Combither Forte 80 mg/480 mg Tablet is a combination of two antiparasitic medicines: Artemether and Lumefantrine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Combither Forte 80 mg/480 mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Combither Forte 80 mg/480 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Combither Forte 80 mg/480 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Combither Forte 80 mg/480 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Combither Forte 80 mg/480 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combither Forte 80 mg/480 mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe kidney disease.

Liver

CAUTION

Combither Forte 80 mg/480 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Combither Forte 80 mg/480 mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe liver disease.

What if you forget to take Combither Forte Tablet?

If you miss a dose of Combither Forte 80 mg/480 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Combither Forte 80 mg/480 mg Tablet

₹14.2/Tablet

Lumerax 80 Tablet

Ipca Laboratories Ltd

₹28.5/tablet

101% costlier

Lumet 80 Tablet

Cipla Ltd

₹28.56/tablet

101% costlier

Falcinil Lfx 80 mg/480 mg Tablet

Zuventus Healthcare Ltd

₹28.56/tablet

101% costlier

Lumart 80 Tablet

McW Healthcare

₹24/tablet

69% costlier

Maladex 80 mg/480 mg Tablet

BestoChem Formulations India Ltd

₹23/tablet

62% costlier

View all substitutes

Quick tips

You have been prescribed Combither Forte 80 mg/480 mg Tablet for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications such as chloroquine.
Tips to reduce the chance of being bitten by mosquitoes:
- Wear light-coloured and covered clothing when you are outside after sunset.
- Use insect repellent creams or sprays on parts of your body not covered by clothing.
- Spray to kill any mosquitoes that may have entered rooms in spite of screening.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
It should be taken with food or drinks rich in fat such as milk.
It may cause fatigue and dizziness. Use caution while driving or doing anything that requires concentration.
If you vomit within 1 hour of taking the tablets, take another dose.
Inform your doctor if you have kidney, liver or heart disease.

Fact Box

Habit Forming

Therapeutic Class

ANTI MALARIALS

Patient concerns

Typhoid.treament feom doctor is xone injection and combither syruo My daughter has typhoid Whay should i do

Dr. Gopal Bansilal Samdani

Paediatrics

Please share your few recent prescriptions and Reports of investigations done in recent past for this problem. Your Question is not very clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.

Which medicine use for Malaria? What is eating in Malaria?

Dr. Saurav Arora

Homeopathy

The medicine depends upon symptoms and stage of disease

I have fever since last four days, I was prescribed zifi 200 and zerodol p by my doctor, but I started getting rashes, reactions, so the doctor stopped the meds, and said to have crocin only, now fourth day is over, fever comes down after having crocin then comes back again. Body ache, and headache is there, fever reaches 103, 103.8 easily every morning, have pain in my eyes also. Had zathrin 250 in the morning and at night today with crocin, my doctor suggested it on phone. What do I have? And why am I not getting better? What medication should I take?

Dr. Pushkar Mani

Physician

do malaria card test & widal

User feedback

Patients taking Combither Forte 80 mg/480 mg Tablet

Twice A Day

88%

Thrice A Day

Once A Day

What are you using Combither Forte Tablet for?

Malaria

81%

Others

19%

How much was the improvement?

Poor

42%

Average

33%

Excellent

25%

What were the side-effects while using Combither Forte 80 mg/480 mg Tablet?

No Side Effec*

25%

Joint pain

25%

Weakness

25%

Headache

25%

*No Side Effect

How do you take Combither Forte Tablet?

With food

100%

Please rate Combither Forte 80 mg/480 mg Tablet on price

Average

67%

Expensive

33%

FAQs

How to take Combither Forte 80 mg/480 mg Tablet?

Take Combither Forte 80 mg/480 mg Tablet with food, exactly as prescribed by your doctor. This medicine is usually taken twice a day with a meal for 3 days, or as directed. On your first day of treatment, take your first dose with food, followed by your second dose 8 hours later. Then for the next 2 days, take one dose in the morning and one dose in the evening. Patients should be encouraged to resume normal eating as soon as food can be tolerated, since this improves the absorption of the medicine.

Can I take Combither Forte 80 mg/480 mg Tablet while I am pregnant?

No, Combither Forte 80 mg/480 mg Tablet is considered to be harmful for women in their first trimester of pregnancy. The reason being, it increases the chances of fetal loss.

Are there any specific contraindications associated with the use of Combither Forte 80 mg/480 mg Tablet?

The use of Combither Forte 80 mg/480 mg Tablet is considered to be harmful for patients with a known hypersensitivity to any of the active or inactive ingredients of the medicine. Caution is advised in patients with cases of severe malaria and in the first trimester of pregnancy.

What should I know about the storage and disposal of Combither Forte 80 mg/480 mg Tablet?

It is advised to keep this medicine in the container it came in, tightly closed. It should be kept out of reach of children. Store it at room temperature and away from excess heat and moisture.

Related lab tests

Malarial Falciparum & Vivax Antigen

Malarial Parasite Identification

Peripheral Smear Examination

Peripheral Smear for Malaria

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Artemether+Lumefantrine. Camberley Surrey: Novartis Pharmaceuticals UK Ltd.; 1999 [revised 31 May 2017]. [Accessed 10 Apr. 2019] (online) Available from:
Artemether/lumefantrine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009. [Accessed 10 Apr. 2019] (online) Available from:

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd

Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

Country of origin: India

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