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Combinase AQ Nasal Spray 1
Combinase AQ Nasal Spray 2
Combinase AQ Nasal Spray 3
Combinase AQ Nasal Spray 4
Combinase AQ Nasal Spray 5
Combinase AQ Nasal Spray 6
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Product Summary :

Combinase AQ Nasal Spray is a combination medicine containing azelastine (an antihistamine) and fluticasone (a corticosteroid). It is used to relieve symptoms of allergic rhinitis, such as sneezing, runny or blocked nose, nasal itching, and postnasal drip. Common side effects include nosebleeds, headache, and taste change. Inform your doctor if you have glaucoma, cataracts, recent nasal surgery, or a nasal infection. Use it regularly as prescribed for effective symptom control.


Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Nov 2026 | 01:02 AM (IST)
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7 ml Nasal Spray
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Product expires after Apr, 2027

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Combinase AQ Nasal Spray 1
Combinase AQ Nasal Spray 2
Combinase AQ Nasal Spray 3
Combinase AQ Nasal Spray 4
Combinase AQ Nasal Spray 5
Combinase AQ Nasal Spray 6

Product introduction

Combinase AQ Nasal Spray is a medicine used to relieve symptoms of allergic rhinitis, such as sneezing, a runny or blocked nose, nasal itching, and watery eyes. It blocks the action of histamine, a substance responsible for symptoms such as sneezing, itching, and a runny nose, and reduces inflammation inside the nose.

Use Combinase AQ Nasal Spray in the dose and duration instructed by your doctor. Do not use it more often or for longer than recommended. Blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril.


The most common side effects are taste changes, nosebleeds, and headache. It may also cause nasal irritation or discomfort, sneezing after administration, and dry nose or throat in some people. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.


Do not take Combinase AQ Nasal Spray if you have a known hypersensitivity or allergy to fluticasone furoate, azelastine hydrochloride, or any excipient in the product. Patients who have experienced previous severe allergic reactions to intranasal corticosteroids or antihistamines should avoid this medicine. It should also be used with caution in patients with recent nasal ulcers, nasal surgery, nasal injury, nosebleeds, or active infections.

Uses of Combinase AQ Nasal Spray

  • Treatment of Allergic rhinitis

Benefits of Combinase AQ Nasal Spray

Treatment of Allergic rhinitis
Allergic rhinitis is a condition that causes symptoms such as sneezing, runny or blocked nose, nasal itching, and postnasal drip, which can interfere with daily activities. Combinase AQ Nasal Spray helps relieve these symptoms by reducing allergic reactions, inflammation, and swelling inside the nose. It makes breathing through the nose easier and helps reduce discomfort caused by allergies.

Side effects of Combinase AQ Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combinase AQ
  • Nosebleeds
  • Headache

How to use Combinase AQ Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Combinase AQ Nasal Spray works

Combinase AQ Nasal Spray contains fluticasone furoate and azelastine hydrochloride, which work together to relieve symptoms of allergic rhinitis such as sneezing, runny nose, nasal congestion, and itching. Azelastine hydrochloride is an antihistamine that blocks H1 receptors, preventing the action of histamine, a chemical released during allergic reactions. This helps reduce sneezing, itching, and nasal discharge. Fluticasone furoate is a corticosteroid with potent anti-inflammatory activity. It suppresses the release of inflammatory mediators and reduces the activity of cells involved in allergic inflammation, including mast cells, eosinophils, and lymphocytes. This helps relieve nasal swelling, congestion, and inflammation.

Dosage

The recommended dose of Combinase AQ Nasal Spray is one spray in each nostril twice daily, in the morning and evening, or as directed by your doctor. The dose and duration of treatment depend on your condition and response to the medicine. Do not exceed the prescribed dose without consulting your doctor.

Quick tips

  • Use Combinase AQ Nasal Spray regularly as prescribed, even if your allergy symptoms improve. Regular use helps maintain symptom control.
  • Blow your nose gently before using the spray to clear your nostrils and allow the medicine to reach the nasal lining.
  • Keep your head slightly tilted forward while spraying. Avoid tilting it backwards, as this may cause the medicine to flow into your throat and leave a bitter taste.
  • Avoid spraying directly onto the nasal septum (the wall separating your nostrils) to reduce irritation and the risk of nosebleeds.
  • Avoid getting the spray into your eyes. Rinse your eyes with water if accidental contact occurs.
  • Combinase AQ Nasal Spray may cause drowsiness or dizziness in some people. Avoid driving or operating machinery if you experience these effects.
  • Inform your doctor if you have frequent nosebleeds, recent nasal surgery, or an untreated nasal infection before using this medicine.
  • Tell your doctor if you have glaucoma, cataracts, or changes in vision, as prolonged use of nasal corticosteroids may require eye monitoring.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Combinase AQ Nasal Spray during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Combinase AQ Nasal Spray during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Combinase AQ Nasal Spray is used to relieve symptoms of allergic rhinitis, such as sneezing, a runny or blocked nose, nasal itching, and postnasal drip. It is particularly useful when treatment with either a nasal antihistamine or a corticosteroid alone does not provide adequate relief.
Combinase AQ Nasal Spray contains two medicines that work in different ways to relieve nasal allergy symptoms. Azelastine blocks the action of histamine, a substance responsible for symptoms such as sneezing, itching, and a runny nose. Fluticasone reduces inflammation inside the nose, helping relieve swelling and nasal congestion.
Combinase AQ Nasal Spray may start relieving nasal allergy symptoms within about 30 minutes of use. However, the time taken to experience relief may vary between individuals. Continue using it regularly as prescribed, even if your symptoms begin to improve.
Yes, Combinase AQ Nasal Spray is intended for regular use during the period when you experience allergic rhinitis symptoms. Using it consistently as prescribed helps maintain symptom control. Do not use more than the recommended dose or continue treatment longer than advised without consulting your doctor.
A bitter taste is a side effect of Combinase AQ Nasal Spray. This happens when the medicine flows towards the throat after spraying. Keeping your head slightly tilted forward and avoiding tilting it backwards may help reduce this effect. If you experience a bitter taste, drinking a soft drink may help it go away.
Yes, nosebleeds are a known side effect of Combinase AQ Nasal Spray. The medicine may also cause irritation, dryness, or discomfort inside the nose. Consult your doctor if you experience persistent nosebleeds, and seek medical attention if bleeding is severe.
There is limited information about the use of Combinase AQ Nasal Spray during pregnancy and breastfeeding. It is not known whether Combinase AQ Nasal Spray pass into human breast milk following nasal administration. Consult your doctor before using this medicine if you are pregnant, planning a pregnancy, or breastfeeding.
Do not stop using Combinase AQ Nasal Spray without consulting your doctor. Regular use may be necessary to maintain relief from allergic rhinitis symptoms, particularly during ongoing exposure to allergens. Your doctor will advise when the treatment can be reduced or discontinued.
Prolonged use of nasal corticosteroids, including fluticasone, may increase the risk of eye problems such as glaucoma or cataracts in some patients. Inform your doctor if you have a history of these conditions or experience blurred vision or other visual disturbances. Your doctor may recommend regular eye examinations if necessary.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Twice A Day
60%
Once A Day
40%
Others
69%
Severe allergic reactions
15%
Asthma
8%
Allergic conditions
8%
Average
51%
Excellent
39%
Poor
10%
Headache
25%
Taste change
25%
Nosebleeds
12%
Sleepiness
12%
No Side Effect
12%
With or without food
75%
With food
17%
Empty stomach
8%
Expensive
79%
Average
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Combinase AQ Nasal Spray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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