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COMBIgan Ophthalmic Solution

Timolol (5mg/ml)+ Brimonidine (2mg/ml)
Genuine
Authenticity Assured
Prescription
required
COMBIgan Ophthalmic Solution is a prescription medicine used for the treatment of pressure in the eyes (ocular hypertension) and glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 22 Dec 2025 | 02:55 PM (IST)
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COMBIgan Ophthalmic Solution
COMBIgan Ophthalmic Solution
packet of 5 ml Ophthalmic Solution
₹77.0 per ml
₹453
₹502
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₹385

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₹1200
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by AbbVie Therapeutics India Private Limited
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Brimocom PF Eye Drop
Brimocom PF Eye Drop
bottle of 5 ml Ophthalmic Solution
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by Cipla Health Ltd

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The content is shown in English
COMBIgan Ophthalmic Solution image
COMBIgan Ophthalmic Solution image
COMBIgan Ophthalmic Solution image
COMBIgan Ophthalmic Solution image

Product introduction

COMBIgan Ophthalmic Solution is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. Check the label thoroughly for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better.


The most common side effects include burning, irritation, itching, and redness at the application site, sleepiness, and decreased alertness. If these side effects persist for a longer duration, inform your doctor. 


In case of accidental contact with your nose or mouth, immediately rinse it off with plenty of water. Do not drive or operate heavy machinery immediately after the use of this medicine as it may cause temporary blurring of vision and may affect your ability to drive.

Uses of COMBIgan Ophthalmic Solution

Benefits of COMBIgan Ophthalmic Solution

Treatment of Glaucoma
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by an abnormally high pressure in the eye. COMBIgan Ophthalmic Solution is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Treatment of Ocular hypertension
Ocular hypertension is a condition where the pressure inside the eye is higher than normal eye pressure due to fluid build-up. COMBIgan Ophthalmic Solution increases the flow of fluid from inside the eye into the bloodstream thereby lowering the increased eye pressure. This prevents further damage or complications such as change in vision or even loss of vision. You should only use COMBIgan Ophthalmic Solution in the affected eye and take it regularly as prescribed by your doctor.

Side effects of COMBIgan Ophthalmic Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of COMBIgan
  • Eye itching
  • Conjunctival redness
  • Allergic conjunctivitis
  • Stinging in the eyes
  • Eye redness
  • Burning sensation in eye
  • Stinging sensation

How to use COMBIgan Ophthalmic Solution

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

How COMBIgan Ophthalmic Solution works

COMBIgan Ophthalmic Solution is a combination of two medicines: Timolol and Brimonidine. Timolol is a beta blocker while Brimonidine is a sympathomimetic. They work by decreasing the production of aqueous humor (fluid in the eye), thereby lowering the increased eye pressure.

All substitutes for COMBIgan Ophthalmic Solution

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • COMBIgan Ophthalmic Solution is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
  • Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
  • If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
  • Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
  • Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
  • It may cause short term blurring of vision when first used. Use caution before driving or using machines.
  • It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
  • Make sure to use within 4 weeks of opening the bottle.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of COMBIgan Ophthalmic Solution during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of COMBIgan Ophthalmic Solution during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
COMBIgan Ophthalmic Solution may cause temporary visual disturbances. Do not drive until your vision is clear.
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Wash your hands before applying COMBIgan Ophthalmic Solution to avoid contamination, and do not touch the tip of the dropper. If you wear contact lenses, remove them before using COMBIgan Ophthalmic Solution. For applying COMBIgan Ophthalmic Solution, tilt your head back, look up, and pull down the lower eyelid to make a pouch and then put the drops in the pouch.
No, COMBIgan Ophthalmic Solution should be continued as advised by the doctor. If any problems are experienced due to the use of COMBIgan Ophthalmic Solution, consult the doctor for re-evaluation.
COMBIgan Ophthalmic Solution can blur your eyes for a short period of time. Avoid driving or operating machinery just after using COMBIgan Ophthalmic Solution.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
COMBIgan Ophthalmic Solution should not be used by patients who are hypersensitive to Timolol, Brimonidine or any of its constituents. This medicine should be avoided in patients who have airway disease, lung disease or heart disease. This medicine should not be used in children who are 2 years old or younger.

Fact Box

Habit Forming

No

Therapeutic Class

OPHTHAL
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Twice A Day
80%
Once A Day
20%
Glaucoma
94%
Others
6%
Average
46%
Excellent
45%
Poor
9%
Burning sensation in eye
24%
No Side Effect
18%
Blurred vision
12%
Eye redness
12%
Headache
12%
With or without food
88%
With food
8%
Empty stomach
4%
Expensive
51%
Average
28%
Not Expensive
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AbbVie Therapeutics India Private Limited
Address: Kasturba road,Bangalore,Karnataka 560001

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver COMBIgan Ophthalmic Solution. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Why we need a prescription?
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Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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