Combiflam Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 01 Apr 2026 | 05:21 PM (IST)

Product Summary :

Combiflam Tablet is a combination of ibuprofen (an NSAID) and paracetamol (an analgesic and antipyretic). It is used to relieve pain and fever, such as headache, toothache, muscle pain, and minor injuries. It works by reducing chemical messengers that cause pain, inflammation, and fever. Take it with food to reduce stomach upset and use it as prescribed. Common side effects include nausea, stomach pain, dizziness, and indigestion. Avoid use in patients with a history of stomach ulcers or bleeding, severe liver disease, or allergy to NSAIDs.

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General Information

Contains

Ibuprofen (400mg)+ Paracetamol (325mg)

Marketer

Sanofi Consumer Healthcare India Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Combiflam Tablet contains two painkiller medicines. They work together to reduce pain, fever, and inflammation. It is used to treat many conditions such as headache, muscle pain, pain during periods, toothache, and joint pain.

Take Combiflam Tablet with food to reduce the risk of an upset stomach. The dose and how often you need it will be decided by your doctor. Medicines used to treat pain are usually best taken at the first sign of pain. It is meant for short-term use only. Consult your doctor if the symptoms persist or worsen or if the medicine is required for use beyond 3 days.

Side effects are rare if this medicine is used correctly, but it may cause heartburn, indigestion, nausea, vomiting, headache, and stomach pain in some people. Consult your doctor if any of these bother you or do not go away.

Before taking Combiflam Tablet, let your doctor know if you are using blood-thinning medicines, or have asthma or any liver or kidney problems. It may affect the dose or suitability of this medicine. Pregnant or breastfeeding women should consult their doctor before taking this medicine. Let your doctor know about all the other medicines you are taking, as they may affect, or be affected by, this medicine. It is best to avoid drinking alcohol while using this medicine.

Uses of Combiflam Tablet

Pain relief : Combiflam Tablet helps relieve pain in conditions such as headache, body ache, muscle ache, toothache, menstrual cramps, and minor injuries.
Treatment of Fever : Combiflam Tablet helps relieve fever in conditions such as flu, viral infections, post-vaccination reactions, and other illnesses associated with fever.

Benefits of Combiflam Tablet

Pain relief
Fever is usually a sign of infection or inflammation in the body. Combiflam Tablet helps reduce high temperature by blocking chemical messengers that cause fever. This helps bring down the temperature and relieve associated symptoms such as body aches and discomfort. Take it as advised, using the lowest effective dose for the shortest duration.

Treatment of Fever
Pain and inflammation can occur due to injury, strain, or underlying conditions. Combiflam Tablet works through different mechanisms to reduce pain, swelling, and inflammation. This provides effective relief from conditions such as headache, migraine, back pain, menstrual cramps, dental pain, and muscle aches.

Side effects of Combiflam Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combiflam

Heartburn
Indigestion
Nausea
Stomach pain
Vomiting
Headache
Sleepiness

How to use Combiflam Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combiflam Tablet should be taken with or after food.

How Combiflam Tablet works

Combiflam Tablet is a combination of two medicines: Ibuprofen and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Dosage

The dose of Combiflam Tablet depends on the severity of your pain or fever, your age, and your overall health. It is usually taken two or three times a day, depending on your doctor’s advice. Your doctor will decide the right dose and duration of treatment for you.

Take Combiflam Tablet exactly as prescribed and do not take more than the recommended dose. Try to take the medicine at evenly spaced times each day if multiple doses are advised. Use it only for the duration recommended by your doctor. If your symptoms do not improve or worsen during treatment, consult your doctor.

Missed Dose

If you miss a dose of Combiflam Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Overdose

Overdose may cause nausea, vomiting, abdominal pain, dizziness, drowsiness, or gastrointestinal bleeding. Severe toxicity may result in liver damage, kidney impairment, low blood pressure, seizures, or metabolic acidosis.

In case of suspected overdose, seek immediate medical attention. The doctor may initiate gastric lavage, activated charcoal, and supportive management, including monitoring of liver and kidney function.

All substitutes for Combiflam Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Combiflam Tablet with food to reduce stomach irritation.
Take Combiflam Tablet exactly as prescribed by your doctor, and avoid prolonged use without medical supervision.
Long-term or excessive use of Combiflam Tablet may increase the risk of stomach bleeding and kidney problems.
Do not take Combiflam Tablet with other medicines containing paracetamol without consulting your doctor.
Avoid taking Combiflam Tablet with other NSAIDs (such as ibuprofen, diclofenac, or naproxen) unless advised by your doctor.
Avoid alcohol while taking Combiflam Tablet, as it may increase drowsiness and the risk of stomach or liver problems.
Watch for warning signs such as severe stomach pain, vomiting blood, or black/tarry stools, and seek medical attention immediately.
Stay well hydrated while taking Combiflam Tablet, especially during fever or hot weather.
Inform your doctor if you have a history of asthma triggered by painkillers before taking Combiflam Tablet.
If dizziness occurs after taking Combiflam Tablet, avoid driving or activities requiring alertness.
Consult your doctor if pain or fever persists for more than a few days despite taking Combiflam Tablet

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Combiflam Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Combiflam Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Combiflam Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Combiflam Tablet is unsafe to use in patients with kidney disease and should be avoided.

Liver

UNSAFE

Combiflam Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What are the side effects of Combiflam Tablet?

Combiflam Tablet may cause side effects such as nausea, vomiting, stomach pain, heartburn, diarrhea, or dizziness in some people. These effects are usually mild and may improve if the medicine is taken with food or milk. Some people may also feel tired or lightheaded. In rare cases, repeated use may affect kidney function or increase blood pressure, particularly in people who are dehydrated or have existing health problems. If side effects persist, worsen, or become severe, consult your doctor.

Can I stop taking Combiflam Tablet when my pain is relieved?

If you are using Combiflam Tablet for short-term pain or fever, you can usually stop taking it once your symptoms improve. However, if it has been prescribed for a condition that causes long-term pain, you should continue taking it for the duration recommended by your doctor. Always follow your doctor’s instructions before stopping any medication.

What is Combiflam Tablet and what is it used for?

Combiflam Tablet is a medicine used for short-term relief of pain and fever. It is commonly prescribed for conditions such as headache, body aches, toothache, sore throat pain, muscle pain, joint pain, and inflammation-related discomfort. It works by lowering fever and reducing substances in the body that cause pain and swelling. While it helps relieve symptoms, it does not treat the underlying cause of the illness. If pain or fever continues, consult your doctor.

Who should not take Combiflam Tablet?

Combiflam Tablet should not be taken by people who are allergic to this medicine or to other similar pain relievers known as NSAIDs. It is also not recommended for individuals with stomach ulcers or stomach bleeding, severe liver or kidney disease, uncontrolled high blood pressure, or heart failure unless advised by a doctor. Long-term or improper use may harm the stomach, kidneys, or liver. Always inform your doctor about your medical history before taking Combiflam Tablet.

Is Combiflam Tablet helpful for relieving stomach pain?

Combiflam Tablet should not be used to treat stomach pain without consulting a doctor. This medicine may increase the risk of stomach irritation and could worsen an underlying stomach condition, such as gastritis or ulcers. If you have persistent stomach pain, it is important to seek medical evaluation rather than self-medicating.

Can I take an extra Combiflam Tablet for pain?

No, taking more than the recommended dose of Combiflam Tablet is not safe and will not necessarily provide better pain relief. Higher doses can increase the risk of side effects such as nausea, vomiting, stomach irritation, heartburn, and diarrhoea. Repeated or excessive use may also cause kidney damage or liver damage. If the prescribed dose does not control your pain or fever, consult your doctor instead of increasing the dose on your own.

Is Combiflam Tablet safe during pregnancy?

Combiflam Tablet is generally not recommended during pregnancy unless your doctor specifically advises it. One of its components, ibuprofen, may affect the baby’s circulation and kidney function, especially during the later stages of pregnancy. Because of these risks, pregnant women should avoid self-medicating with this medicine. If you experience pain or fever during pregnancy, consult your doctor so a safer treatment option can be recommended.

Is Combiflam Tablet safe for children with a fever?

Combiflam Tablet should only be given to children if advised by a doctor. Children require doses based on their age and weight, and certain medicine combinations may not be suitable for all ages. Although it can reduce fever and pain, improper use may increase the risk of overdose, especially if other medicines contain similar ingredients. Consult a doctor before giving Combiflam Tablet to a child.

Can ibuprofen reduce fever?

Yes, ibuprofen can help reduce fever by lowering substances in the body called prostaglandins that are involved in inflammation and temperature regulation. However, fever may return until the underlying cause is treated. If fever lasts more than a few days or the person appears very unwell, medical advice should be sought.

Can I drink alcohol while taking Combiflam Tablet?

It is best to avoid alcohol while taking Combiflam Tablet. Alcohol can increase the risk of stomach irritation and bleeding when combined with ibuprofen, and it may also increase the risk of liver damage when combined with paracetamol. If you regularly consume alcohol, discuss this with your doctor before taking Combiflam Tablet.

What foods should be avoided while taking ibuprofen?

While taking Combiflam Tablet, avoid alcohol and avoid taking the medicine on an empty stomach. If spicy or heavy foods worsen acidity or heartburn, it may help to eat lighter meals during treatment. If you develop stomach pain, black stools, or vomiting that looks like blood, seek medical attention immediately.

Can Combiflam Tablet treat an infected tooth?

Combiflam Tablet may temporarily reduce pain and inflammation from a tooth infection, but it does not treat the infection itself. Dental infections can spread and may cause swelling, fever, or a bad taste in the mouth. If you suspect a tooth infection, you should consult a dentist or doctor promptly for proper treatment.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Related lab tests

Complete Blood Count

References

User feedback

Patients taking Combiflam Tablet

Once A Day

60%

Twice A Day

40%

What are you using Combiflam Tablet for?

Pain relief

55%

Fever

25%

Others

10%

Headache

Dental pain

How much was the improvement?

Excellent

42%

Average

41%

Poor

17%

What were the side-effects while using Combiflam Tablet?

No Side Effect

79%

Stomach pain

Indigestion

Heartburn

Nausea

How do you take Combiflam Tablet?

With food

77%

With or without food

19%

Empty stomach

Please rate Combiflam Tablet on price

Not Expensive

40%

Average

35%

Expensive

26%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sanofi Consumer Healthcare India Limited
Address: Unit No. 2, G-16/2 & 3, MIDC, Tarapur - 401506/Unit 1104, 11th Floor, Godrej Two, Pirojshanagar, Eastern Express Highway, Vikhroli East, Mumbai, Maharashtra, 400079

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Combiflam Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Combiflam Tablet

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Combiflam Tablet

Benefits of Combiflam Tablet

Side effects of Combiflam Tablet

How to use Combiflam Tablet

How Combiflam Tablet works

Dosage

Missed Dose

Overdose

All substitutes for Combiflam Tablet

Ibufyl Plus Tablet

Flexib 325 Tablet

Flexon Tablet

Fenceta 400mg/325mg Tablet

Duoflam P 400mg/325mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What are the side effects of Combiflam Tablet?

Can I stop taking Combiflam Tablet when my pain is relieved?

What is Combiflam Tablet and what is it used for?

Who should not take Combiflam Tablet?

Is Combiflam Tablet helpful for relieving stomach pain?

Can I take an extra Combiflam Tablet for pain?

Is Combiflam Tablet safe during pregnancy?

Is Combiflam Tablet safe for children with a fever?

Can ibuprofen reduce fever?

Can I drink alcohol while taking Combiflam Tablet?

What foods should be avoided while taking ibuprofen?

Can Combiflam Tablet treat an infected tooth?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

References

User feedback

Patients taking Combiflam Tablet

What are you using Combiflam Tablet for?

How much was the improvement?

What were the side-effects while using Combiflam Tablet?

How do you take Combiflam Tablet?

Please rate Combiflam Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests