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MD (Pharmacology), MBBS
Last updated:
14 Dec 2020 | 11:45 AM (IST)
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Combifen 400mg/325mg/25mg Tablet

Prescription Required
Manufacturer
Storage
Store at room temperature (10-30°C)

Introduction

Combifen 400mg/325mg/25mg Tablet is a pain relieving medicine. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Combifen 400mg/325mg/25mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, indigestion, stomach pain, and diarrhea. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Combifen Tablet

Benefits of Combifen Tablet

In Pain relief

Combifen 400mg/325mg/25mg Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It also helps to manage short term symptoms such as back pain, toothache or pain in the ear and throat. It works by reducing substances in the body that cause pain and swelling. Combifen 400mg/325mg/25mg Tablet also reduces fever associated with any painful conditions. This medicine does not cause acidity due to the presence of Magnesium oxide in it.

Side effects of Combifen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combifen

  • Nausea
  • Indigestion
  • Stomach pain
  • Diarrhea

How to use Combifen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combifen 400mg/325mg/25mg Tablet is to be taken with food.

How Combifen Tablet works

Combifen 400mg/325mg/25mg Tablet is a combination of three medicines: Ibuprofen, Paracetamol and Magnesium Oxide which relieve pain. Ibuprofen is a non-steroidal antiinflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Magnesium Oxide is an inorganic salt which reduces the amount of acid in the stomach and prevents damage to the stomach lining caused by Ibuprofen.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Combifen 400mg/325mg/25mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Combifen 400mg/325mg/25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Combifen 400mg/325mg/25mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Combifen 400mg/325mg/25mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Combifen 400mg/325mg/25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combifen 400mg/325mg/25mg Tablet may be needed. Please consult your doctor.
Use of Combifen 400mg/325mg/25mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.
Liver
CAUTION
Combifen 400mg/325mg/25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combifen 400mg/325mg/25mg Tablet may be needed. Please consult your doctor.
However, the use of Combifen 400mg/325mg/25mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient Concerns

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Plz dr. suggest me periods pain reliefer tablet which available easily at store.
Dr. Megha Tuli
Obstetrics and Gynaecology
You can take govern tablets for pain relief
Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tablet Crocin pain relief can. E given
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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ibuprofen. North Harrow, Middlesex: Accord Healthcare Limited; 2016 [revised 16 Mar. 2018]. [Accessed 29 Apr. 2019] (online) Available from:External Link
  2. Paracetamol. Barnstaple, Devon: Actavis UK Ltd.; 1980 [revised 23 Dec. 2016]. [Accessed 29 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Magnesium oxide. [Accessed 29 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

24,Industrial Area ,Ambala Cantt. , Haryana State (India)
Country of Origin: India

Best Price
₹11.03
MRP12.98  Get 15% OFF
Inclusive of all taxes
Best price is valid on orders above ₹499
10 tablets in 1 strip
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