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Colisig 3 Injection

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Colisig 3 Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It is commonly used for critically ill patients admitted to the hospital.
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General Information

Contains

Colistimethate Sodium (3Million IU)

Marketer

Signity Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Colisig 3 Injection image
Colisig 3 Injection image

Product introduction

Colisig 3 Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits.

Common side effects of this medicine include gastrointestinal upset, slurred speech, dizziness, vertigo, fever, rash, and paresthesia. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell the doctor if you are allergic to any antibiotic or have any liver or kidney problems. Pregnant or breastfeeding mothers should consult their doctor before using it. Your doctor may get regular blood tests done to monitor kidney function and the level of the medicine in your blood.

Uses of Colisig Powder for Injection

  • Severe bacterial infections

Benefits of Colisig Powder for Injection

Severe bacterial infections
Colisig 3 Injection is an antibiotic that works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections. This medicine is usually given as an injection by a doctor or nurse and should not be self-administered at home.
This medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Colisig Powder for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Colisig
  • Slurred speech
  • Rash
  • Fever
  • Upset stomach
  • Gastrointestinal disturbance
  • Generalized itching
  • Red spots or bumps
  • Increased blood urea nitrogen
  • Increased creatinine level in blood
  • Decreased creatinine clearance
  • Respiratory distress
  • Apnea (absence of breathing)
  • Renal toxicity
  • Decreased urinary volume
  • Dizziness
  • Paresthesia (tingling or pricking sensation)
  • Vertigo

How to use Colisig Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Colisig Powder for Injection works

Colisig 3 Injection is an antibiotic. It kills bacteria by destroying the bacterial cell membrane.

Quick tips

  • Colisig 3 Injection is an antibiotic that is usually only given in the hospital for serious infections.
  • It is given by injection or drip (infusion) into a vein usually over 30-60 minutes.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Your doctor may get regular blood tests done to monitor the level of the medicine in your blood.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Colisig 3 Injection does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Colisig 3 Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Colisig 3 Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
Colisig 3 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Colisig 3 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Colisig 3 Injection in patients with liver disease.

Frequently asked questions

Before taking Colisig 3 Injection, you must tell your doctor if you have or ever had any problems related to your kidneys or lungs (such as asthma). Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Colisig 3 Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Colisig 3 Injection.
Use of Colisig 3 Injection should be avoided in patients who are allergic to Colisig 3 Injection or any of its components. However, if you are not aware of any allergy or if you are using Colisig 3 Injection for the first time, consult your doctor.
Enough evidence is not available to provide clarity on the use of Colisig 3 Injection in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Colisig 3 Injection. You may take it only if prescribed by your doctor.
Colisig 3 Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Before taking Colisig 3 Injection, you must tell your doctor if you have or ever had any problems related to your kidneys or lungs (such as asthma). Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Colisig 3 Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Colisig 3 Injection.
Use of Colisig 3 Injection should be avoided in patients who are allergic to Colisig 3 Injection or any of its components. However, if you are not aware of any allergy or if you are using Colisig 3 Injection for the first time, consult your doctor.
Enough evidence is not available to provide clarity on the use of Colisig 3 Injection in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Colisig 3 Injection. You may take it only if prescribed by your doctor.
Colisig 3 Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

Polypeptides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Cell membrane active agent

Related lab tests

Complete Blood Count

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 324-25.
  2. Colistimethate. Rochester, Michigan: JHP Pharmaceuticals, LLC.; 2013. [Accessed 11 Feb. 2019] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Signity Pharmaceuticals Pvt Ltd
Address: PLOT NO. 10, FLAT NO. 1, GROUND FLOOR DNYANYOG APARTMENT, DEO NAGAR, KHAMLA ROAD NAGPUR Nagpur MH 440015 IN , - , .

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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