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food interaction for COLIGON-O

alcohol interaction for COLIGON-O

pregnancy interaction for COLIGON-O

lactation interaction for COLIGON-O

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Human and animal studies are not available. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Dicyclomine(10 mg)


Dicyclomine is used to treat periodic spasms and pain in abdomen and stomach, intestinal cramps, irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits) and inability to control urine (urinary incontinence).

How it works

Dicyclomine belongs to antispasmodic and anticholinergic (antimuscarinic) class of medicines that act by relieving the smooth muscle tightening (contraction) of the gastrointestinal tract via dual action: (i) by a specific action (anticholinergic), which reduces muscle contractions and (ii) by a direct effect on muscles of the stomach and intestine (musculotropic) leading to muscle relaxations, and decrease in contraction and pain.

Common side effects

Flatulence, Abdominal bloating, Blurred vision, Gastrointestinal discomfort, Constipation, Dizziness, Drowsiness, Weakness, Dry mouth, Difficulty in urination, Headache, Loss of appetite, Stomach pain, Vomiting
Magaldrate(400 mg)


Magaldrate, given alone or in combination with antiflatulent (simethicone) drugs to treat indigestion (dyspepsia), heartburn, gas, and other digestive problems.

How it works

Magaldrate belongs to group of medicines called antacids. It rapidly neutralizes or buffers existing acid in stomach .

Common side effects

Nausea, Memory loss, Brittle bone, Constipation, Diarrhoea, Intestinal pain, Loss of appetite, Muscle weakness, Slow reflexes, Vomiting
Oxetacaine(10 mg)


Oxetacaine is used to relieve pain associated with several conditions of digestive system like inflammation of the food pipe (esophagitis) or stomach (gastritis), hiatus hernia (protrusion of stomach into esophagus), heartburn of pregnancy, ulcers of the stomach and intestine (peptic ulcer), or long-term bowel disorders (irritable bowel syndrome).

How it works

Oxetacaine belongs to a class of medications called local anesthetics. It acts upon the nerves of the digestive system and stops the nerves from sending signals of pain thus providing relief.

Common side effects

Constipation, Diarrhoea, Dizziness, Weakness, Drowsiness, Dry mouth, Headache, Hypersensitivity reaction, Loss of appetite, Nausea
Simethicone(25 mg)


Simethicone is used to relieve painful pressure, hiccups, bloating and fullness caused by excess gas in the stomach and intestines in adults as well as in children.

How it works

Simethicone belongs to class of medications called surface active substances. It is an antifoaming agents and works by acting on inner lining of intestine and allowing gas bubbles to come together more easily helping to release trapped wind.

Common side effects

Allergic reaction


No substitutes found

Expert advice for COLIGON-O

  • This medication may impair your thinking or alertness. Be careful if you drive or do anything that requires you to be alert.
  • Avoid becoming overheated or dehydrated during exercise and in hot weather. Dicyclomine can decrease your sweating, which can lead to heat stroke in a hot environment.
  • Avoid taking alcohol as it can increase certain side effects of dicyclomine.
  • Stop using dicyclomine and call your doctor right away if you have serious side effects such as confusion, hallucinations, unusual thoughts or behavior, fast or uneven heart rate, or if you urinate less than usual or not at all.

Frequently asked questions for COLIGON-O


Q. Is Dicyclomine safe?
Dicyclomine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is Dicyclomine gluten free?
Dicyclomine active drug does not contain gluten. Read the label instruction of the brands your doctor prescribes you, for gluten content.
Q. Is Dicyclomine an over-the-counter medicine?
Dicyclomine is available over-the-counter. However, always consult your doctor before taking dicyclomine for your disease.
Q. Does dicyclomine help nausea?
Dicyclomine is not known to relieve nausea. Nausea is a common side effect of dicyclomine.
Q. Does dicyclomine help constipation or trigger constipation?
Dicyclomine may cause constipation.
Q. Is dicyclomine an opiate/steroid/antacid/NSAID/benzodiazepine?
Dicyclomine is not an opiate, steroid, or an antacid. It is neither a NSAID not a benzodiazepine.
Q. Is dicyclomine a muscle relaxer?
Yes, dicyclomine is a smooth muscle relaxant. It has a direct effect on muscles of the stomach and intestine. It does not relax the skeletal/voluntary muscles.
Q. Can I take dicyclomine for diarrhea?
Dicyclomine has no known effects in treating diarrhea.
Q. Can I take dicyclomine for menstrual cramps?
Dicyclomine mainly acts on the smooth muscles of the intestine. Hence, it is used to relieve cramps or spasms of the stomach and intestines (gut). It is not known whether it can be used for menstrual cramps.
Q. Does dicyclomine cause constipation?
Dicyclomine may cause constipation.
Q. Does dicyclomine make you drowsy?
Dicyclomine may cause drowsiness and make you feel sleepy.
Q. Does dicyclomine cause hair loss?
Dicyclomine does not have hair loss as a known side-effect.
Q. Can I take dicyclomine with Advil (ibuprofen)/ amoxicillin/ Pepto (bismuth subsalicylate)/ tramadol/ Vicodin (acetaminophen and hydrocodone)/ oxycodone/ Tylenol (paracetamol)?
There are no known serious drug interactions between dicyclomine and Advil (ibuprofen)/ amoxicillin/ Pepto (bismuth subsalicylate)/ Tramadol/ Vicodin (acetaminophen and hydrocodone)/ oxycodone/ Tylenol (paracetamol). Dicyclomine is often available in combination with pain killers like paracetamol Consult your doctor about all medications currently taken before starting and while on dicyclomine.


Q. What is magaldrate and simethicone?
Magaldrate and simethicone are used as antacid and antiflatulent drug in combination therapy. Magaldrate works by neutralizing stomach acid and simethicone works by eliminating the gas from stomach.


Q. Is simethicone antacid?
No. Simethicone is not an antacid. But it is used in preparations which are used as antacid.

Q. Does it contain aspirin?
It does not contain aspirin.
Q. Is simethicone available over the counter?
Yes. Simethicone is sold over the counter without a prescription.
Q. Is simethicone gluten free?
Yes. Simethicone is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Is simethicone safe?
Yes. Simethicone is relatively safe.

Q. Is it safe for babies?
 Safe for infants and babies, if used as recommended. In case of any side-effects, consult your doctor.
Q. Is it safe to take simethicone daily?
It is advisable to take simethicone only as per the instructions of the doctor.
Q. Is simethicone good for gas?
Yes. Simethicone is effective in the treatment of gas.

Q. Does it have any side effects?
 It does not have any known serious side-effects.
Q. Can I take simethicone with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol, or Depakote?
Yes. Simethicone can be taken with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol (bismuth subsalicylate) or Depakote (divalproate sodium), if prescribed by your doctor.
Q. Does simethicone cause nausea or constipation?
Simethicone is not known to cause nausea or constipation. If you experience any such symptoms, please consult your doctor.
Q. Is simethicone effective against acid reflux?
Simethicone is effective in controlling acid reflux if combined with an antacid.


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)