Coldifen Tablet is a combination medicine used to treat common cold symptoms. It thins mucus in the nose, windpipe and lungs making it easier to cough out. It also provides relief from seasonal allergic conditions such as runny nose, watery eyes, sneezing and congestion or stuffiness.
Coldifen Tablet is taken in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, vomiting, stomach upset, headache, insomnia, and loss of appetite. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.
Before taking it, you should tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Coldifen Tablet is a combination of medicines that effectively relieves symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It also blocks the activity of certain chemicals that causes pain and fever. An antacid present in Coldifen Tablet prevents acidity that may occur due to this medicine. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.
Side effects of Coldifen Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Coldifen
Nausea
Vomiting
Upset stomach
Drowsiness
Dizziness
Headache
Allergic reaction
Insomnia (difficulty in sleeping)
Loss of appetite
How to use Coldifen Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coldifen Tablet is to be taken on an empty stomach.
How Coldifen Tablet works
Coldifen Tablet is a combination of three medicines:Fexofenadine, phenylephrine, paracetamol and ambroxol which relieve common cold symptoms. Fexofenadine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Ambroxol is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out.
Safety advice
Alcohol
CAUTION
Alcohol should be used with caution while taking Coldifen Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Coldifen Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CAUTION
Coldifen Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving
NOT RELEVANT
Not relevant, as Coldifen Tablet is intended for use in hospitalized patients.
Kidney
CAUTION
Coldifen Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. May cause excessive sleepiness in patients with end stage kidney disease.
Liver
UNSAFE
Coldifen Tablet is unsafe to use in patients with liver disease and should be avoided.
What if you forget to take Coldifen Tablet?
If you miss a dose of Coldifen Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Coldifen Tablet is prescribed to get relief from symptoms of common cold.
Call your doctor if your symptoms have not improved within seven days of treatment.
Inform your doctor if you are taking any other medications for cold.
It may cause nausea. Stick to simple meals, and do not eat rich or spicy food.
Avoid using antacids 30 minutes before or after taking this medicine. It can make it harder for your body to absorb this medicine.
Along with taking Coldifen Tablet do the following simple tips at home to get relief:
Steam inhalation.
Gargling with warm saltwater.
Apply vapor rubs on chest, back if needed. Take enough rest.
Take warm food and fluid only. Ensure adequate fluid intake.
Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcase, etc.
Fact Box
Habit Forming
No
Therapeutic Class
RESPIRATORY
Patient concerns
common cold,snizning and headache which tab can take to common cold?
Dr. Shubhra Chandan Pradhan
ENT
Take tab LCZ PLUS and consult an ENT specialist for proper clinical examination
Common cold with bronchitis fever two days Fever with common cold & bronchitis
Dr. Gopal Bansilal Samdani
Paediatrics
There are many underlying causes of your symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of child. Please consult me or any other Paediatrician. will take detail history and will examine your child in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. At time may ask you relevant investigations if necessary. Your child may need antibiotics and/or other prescription drugs.
For cough, cold -- Prevent dehydration. Fluids may help thin secretions and soothe an irritated throat. Dry, hacking coughs respond to honey in hot water, tea, or lemon juice. Drink plenty of fluids to replace those lost from sweating and having a runny nose, get plenty of rest, eat healthily ? a low-fat, high-fibre diet is recommended, including plenty of fresh fruit and vegetables. OTC drugs, gargling with salt water and sucking on menthol sweets can help relieve a sore throat and blocked nose, are generally safe for older children and adults to take, but might not be suitable for babies, young children. Avoid applying Vicks VapoRub to babies and toddlers.You should never give children under 4 years of age over-the-counter cough and cold products without checking with your child's doctor. These medicines may harm young children.
For cough, cold -- Prevent dehydration. Fluids may help thin secretions and soothe an irritated throat. Dry, hacking coughs respond to honey in hot water, tea, or lemon juice. Drink plenty of fluids to replace those lost from sweating and having a runny nose, get plenty of rest, eat healthily ? a low-fat, high-fibre diet is recommended, including plenty of fresh fruit and vegetables. OTC drugs, gargling with salt water and sucking on menthol sweets can help relieve a sore throat and blocked nose, are generally safe for older children and adults to take, but might not be suitable for babies, young children. Avoid applying Vicks VapoRub to babies and toddlers.You should never give children under 4 years of age over-the-counter cough and cold products without checking with your child's doctor. These medicines may harm young children. There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you specific treatment.
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References
Picon PD, Costa MB, da Veiga Picon R, et al. Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial. BMC Infect Dis. 2013 Nov 22;13:556. [Accessed 30 Jan. 2026]. Available from: