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Coenac 1000 Solution

Prescription Required

Product introduction

Coenac 1000 Solution is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.

Coenac 1000 Solution is given as an injection under the supervision of a doctor. It must be injected within 8 hours of paracetamol overdose. It can be given up to 24 hours, but medicine effective slow down when given after 24 hours of dosage overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.

The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Coenac Injection

  • Treatment of Paracetamol toxicity

Benefits of Coenac Injection

In Treatment of Paracetamol toxicity

Coenac 1000 Solution is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol which leads to an overdose. Initially, there may be mild gastrointestinal symptoms like nausea, vomiting, stomach pain, irritability, etc. But, if left untreated, paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.

Side effects of Coenac Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Coenac

  • Rash
  • Red spots or bumps
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Itching

How to use Coenac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Coenac Injection works

Coenac 1000 Solution is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralises the toxic products of paracetamol.

Safety advice

Alcohol
SAFE
Consuming alcohol with Coenac 1000 Solution does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Coenac 1000 Solution is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Coenac 1000 Solution is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Coenac 1000 Solution does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Coenac 1000 Solution is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Coenac 1000 Solution may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Coenac 1000 Solution is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Coenac 1000 Solution may not be needed in these patients. Please consult your doctor.

What if you forget to take Coenac Injection?

If you miss a dose of Coenac 1000 Solution, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Coenac 1000 Solution
₹114/Injection
Mucomix 1gm Injection
Samarth Life Sciences Pvt Ltd
₹132.32/injection
12% costlier
Mucyst 1000mg Injection
Neon Laboratories Ltd
₹123.5/injection
5% costlier
Mucomelt 1000mg Injection
Venus Remedies Ltd
₹130.52/injection
11% costlier
Nacel 1000mg Injection
Celon Laboratories Ltd
₹119.7/injection
2% costlier
Mucotroy Injection 5ml
Troikaa Pharmaceuticals Ltd
₹113.84/injection
3% cheaper

Quick tips

  • Coenac 1000 Solution is used for the treatment of paracetamol overdose (when you may have taken too much paracetamol).
  • It protects the liver from damage by the high levels of paracetamol.
  • It is very effective when given during the first 8 hours following paracetamol overdose. The effectiveness is reduced with time but it can still help when given within 24 hours. 

Fact Box

Chemical Class
N-Acylated Alpha Amino Acids
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Acetylcysteine -Mucolytic

Patient concerns

arrow
Ferrous sulphate tablets toxicity
Dr. Megha Tuli
Obstetrics and Gynaecology
There is no toxicity as such. Please be specific in what respect are you asking.
Diazepam toxicity about 45 tablets
Dr. Ambrish Dharmadhikari
Psychiatry
Rush immediately to emergency services
arrow

FAQs

Q. Is Coenac 1000 Solution good for liver?

Yes, Coenac 1000 Solution is good for the liver. It improves liver function and activity in patients with non-alcoholic fatty liver disease. It also prevents liver from toxic agents which can damage the liver. Additionally, it also prevents liver from damage in cases of drug overdose like paracetamol, etc.

Q. Does Coenac 1000 Solution affect blood pressure?

Yes, Coenac 1000 Solution by acting through various mechanism prevents the rise of blood pressure and maintains the normal functioning of the body. There are reports which show that Coenac 1000 Solution can prevent damage to the inner lining of the blood vessels of the body, which will maintain the elasticity and vitality of the blood vessels. It also increases the antioxidants levels in the body hence preventing the body from oxidative damage.

Q. Does Coenac 1000 Solution help anxiety?

There is no concrete evidence that Coenac 1000 Solution can be used alone in the treatment of anxiety disorder. However, in some reports, it is shown that Coenac 1000 Solution provides benefit by acting as an antioxidant. This property prove to be beneficial in psychiatric and neurological conditions when added to the normal treatment of the particular disorder. Do not take this medication without consulting your doctor. Contact the doctor for any query if you feel anxious.

Q. Is Coenac 1000 Solution good for kidneys?

Yes, Coenac 1000 Solution is beneficial when used in patients with impaired kidney functions. It is also used to prevent or minimize the damage caused by the use of contrast during investigations like CT scan or other body scans.

Q. Does Coenac 1000 Solution need to be refrigerated?

Unopened vials of Coenac 1000 Solution should be stored at room temperature. Once the medicine is opened and diluted it should be used within 3 hours as per the directions of the physician. It should not be stored above 25ºC. Once opened, the vials should be stored in refrigeration and if unused then should be discarded after 96 hours.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
  2. Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
  3. Acetylcysteine. Romford, Essex: Martindale Pharma; 2004 [revised 23 Feb. 2017]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  4. Acetylcysteine. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2004 [revised Jun. 2013]. [Accessed 31 Jan. 2019] (online) Available from:External Link
  5. Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun, 2023] (online) Available from:External Link

Marketer details

Name: Koye Pharmaceuticals Pvt ltd
Address: A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070
Country of origin: India
Expires on or after: January, 2025

A licensed vendor partner from your nearest location will deliver Coenac 1000 Solution. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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5.0 ml in 1 ampoule
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