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Clobcore Lotion belongs to a group of medicines called steroids. It is used for the short-term treatment of skin inflammation and itching. It works by preventing the release of substances that cause swelling, redness, and itchiness in the skin.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 07 Jan 2026 | 03:57 PM (IST)
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General Information

Contains

Clobetasone (0.05% w/v)

Marketer

Coremedics Pharmaceutical Pvt. Ltd.

Storage

Store below 25°C
The content is shown in English
Clobcore Lotion image
Clobcore Lotion image
Clobcore Lotion image
Clobcore Lotion image

Product introduction

Clobcore Lotion is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor.


Using Clobcore Lotion does not cause any serious side effects. Let your doctor know if you experience any symptoms while using Clobcore Lotion. They may be able to suggest ways to treat or manage the side effects. However, if you experience any side effects that persist or worsen, let your doctor know.


Before using Clobcore Lotion, let your doctor know if you are using any other medicine for the same condition. Pregnant and breastfeeding women should consult their doctors before using this medicine. This medicine is not recommended for use in children below 12 years of age.

Uses of Clobcore Lotion

  • Treatment of Skin conditions with inflammation & itching

Benefits of Clobcore Lotion

Treatment of Skin conditions with inflammation & itching
Clobcore Lotion is effective in treating skin disorders with inflammation and itching, such as eczema and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin. In treating eczema and dermatitis, it reduces the redness, rash, pain, or itchiness caused by your skin’s reaction to an irritant. Always use Clobcore Lotion as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.

Side effects of Clobcore Lotion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clobcore
  • Limited data available

How to use Clobcore Lotion

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Clobcore Lotion works

Clobcore Lotion is a steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy.

Quick tips

  • Apply Clobcore Lotion to the affected areas as a thin film 2-3 times daily, or as advised by your doctor.
  • Do not use it more often or for longer than advised by your doctor.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • If you think the area of skin you are treating has become infected, you should stop using Clobcore Lotion and consult your doctor.
  • Consult your doctor if your skin condition has not improved after 2 weeks of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Clobcore Lotion is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Clobcore Lotion may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Clobcore with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Mild

Minoxidil (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Before using Clobcore Lotion, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Clobcore Lotion gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.
Yes, clobetasol and Clobcore Lotion are different steroid medications. Clobetasol is a very potent (strong) steroid, whereas Clobcore Lotion is comparatively milder and has been categorized under moderately potent steroids.
Clobcore Lotion is a topical steroid that needs to be applied locally on the affected part. It is a moderately strong steroid. The chances of immunity suppression with Clobcore Lotion are lower than other steroids like clobetasol and betamethasone when applied to the skin. Do consult your physician before you start this medication.
The use of Clobcore Lotion is usually not recommended in children less than 12 years of age. It should only be used if advised by the doctor. Doctors often prescribe this medicine for the treatment of dermatoses (skin infections) in children. The duration of the treatment with Clobcore Lotion does not normally exceed 7 days. If your condition worsens or does not improve within 7 days, consult your doctor.
No, do not stop using Clobcore Lotion without consulting your doctor, even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
If you forget to use Clobcore Lotion, do not worry and continue using Clobcore Lotion as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. If you are not sure and have any other doubts, please consult your doctor.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Glucocorticoids

References

  1. Clobetasone [EMC SmPC]. Uxbridge, Middlesex: GlaxoSmithKline UK; 2008 [revised 2 Aug. 2017]. [Accessed 04 Apr. 2019] (online) Available from:
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
  3. Clobetasone butyrate [product Information]. Abbotsford, Victoria: GlaxoSmithKline Australia Pty Ltd; 2018. [Accessed 09 May 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Coremedics Pharmaceutical Pvt. Ltd.
Address: TIJARA ROAD, KISHAN GARH BASS, KISHANGARH, ALWAR, RAJASTHAN, INDIA, 301405

Vendor Details

Country of origin: India

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