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Cetsafe Plus Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 22 Jan 2026 | 12:56 AM (IST)
Cetsafe Plus Tablet is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It is also used to relieve pain and fever.
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General Information

Contains

Levocetirizine (5mg)+ Phenylpropanolamine (25mg)+ Paracetamol (500mg)

Marketer

Coxswain Healthcare

Storage

Store below 30°C
The content is shown in English
Cetsafe Plus Tablet image
Cetsafe Plus Tablet image

Product introduction

Cetsafe Plus Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, dryness in mouth, headache, fatigue, allergic reactions, high blood pressure, and insomnia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before taking this medicine, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Cetsafe Plus Tablet

Benefits of Cetsafe Plus Tablet

Common cold
Cetsafe Plus Tablet is a combination medicine that effectively relieves symptoms of the common cold, such as a blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier.

Cetsafe Plus Tablet is safe and effective. It usually starts to work within a few minutes, and the effects can last up to several hours. Take it as prescribed by your doctor, and do not stop using it unless you are advised otherwise.

Side effects of Cetsafe Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cetsafe Plus
  • Nausea
  • Dryness in mouth
  • Headache
  • Fatigue
  • Allergic reaction
  • High blood pressure
  • Insomnia (difficulty in sleeping)
  • Palpitations
  • Sleepiness

How to use Cetsafe Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cetsafe Plus Tablet may be taken with or without food.

How Cetsafe Plus Tablet works

Cetsafe Plus Tablet is a combination of three medicines: Levocetirizine, Phenylpropanolamine and Paracetamol which relieve common cold symptoms. Levocetirizine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever.

Quick tips

  • Cetsafe Plus Tablet is prescribed to get relief from symptoms of common cold.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
  • Call your doctor if your symptoms have not improved within seven days of treatment.
  • Inform your doctor if you are taking any other medications for cold.
  • Along with taking Cetsafe Plus Tablet do the following simple tips at home to get relief:
    1. Steam inhalation.
    2. Gargling with warm saltwater.
    3. Apply vapor rubs on chest, back if needed. Take enough rest.
    4. Take warm food and fluid only. Ensure adequate fluid intake.
    5. Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcases, etc.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Cetsafe Plus Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Cetsafe Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Cetsafe Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Cetsafe Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Cetsafe Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Cetsafe Plus Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Cetsafe Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Cetsafe Plus Tablet is not recommended in patients with severe liver disease and active liver disease.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

References

  1. Levocitrizine. Slough, Berkshire: UCB Pharma Limited; 2007 [revised 27 Mar. 2019]. [Accessed 01 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Coxswain Healthcare
Address: 305/306, Bhagtani Enclave, Sonapur Cross Road, Bhandup West, Mumbai - 400078, Behind Asian Paints Nahur

Vendor Details

Country of origin: India

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