Bonspri Solution for Injection
Prescription Required
Product introduction
Bonspri Solution for Injection is used in the treatment of blood cancer (chronic lymphocytic leukemia). It binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.
Bonspri Solution for Injection is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, diarrhea, breathlessness, cough, etc. Let your doctor know if any of these side effects bothers you pr persists for a longer duration of time. Regular blood tests are required to check your blood cells along with heart, liver and kidney function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Bonspri Solution for Injection is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, diarrhea, breathlessness, cough, etc. Let your doctor know if any of these side effects bothers you pr persists for a longer duration of time. Regular blood tests are required to check your blood cells along with heart, liver and kidney function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Bonspri Solution for Injection
Benefits of Bonspri Solution for Injection
In Blood cancer (Chronic lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Bonspri Solution for Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Side effects of Bonspri Solution for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bonspri
- Nausea
- Diarrhea
- Breathlessness
- Cough
- Flushing of skin
- Low energy
- Skin rash
How to use Bonspri Solution for Injection
Your doctor or nurse will guide you how to use this medicine.
How Bonspri Solution for Injection works
Bonspri Solution for Injection is a monoclonal antibody. It specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bonspri Solution for Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Bonspri Solution for Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Bonspri Solution for Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Bonspri Solution for Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Bonspri Solution for Injection is safe to use in patients with kidney disease. No dose adjustment of Bonspri Solution for Injection is recommended.
Liver
UNSAFE
Bonspri Solution for Injection is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Bonspri Solution for Injection is given as an IV infusion under the supervision of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood cell count (CBC), liver and kidney function.
- Inform your doctor if you experience fever, chills, rash, dizziness and shortness of breath during the treatment.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
CD 20 Inhibitor
Interaction with drugs
Taking Bonspri with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of infections.
Do not use Ofatumumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Ofatumumab is essential, ensure a gap
Concurrent use may increase the risk of infections.
Do not use Ofatumumab with Cholera Vaccine (Inactivated). If Ofatumumab is essential, ensure a gap of At least 12 months after
Concurrent use may increase the risk of infections.
Do not use Ofatumumab with Purified Vi Polysaccharide Typhoid Vaccine. If Ofatumumab is essential, ensure a gap of At least 12
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1747-48.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1011.
- Ofatumumab. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Jan. 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Switzerland
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0.4 ml in 1 prefilled syringe
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