Biratrone 500 Tablet

Abiraterone Acetate (500mg)

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Biratrone 500 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Aug 2026 | 01:27 PM (IST)

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General Information

Contains

Abiraterone Acetate (500mg)

Marketer

Medizia Biotech

Storage

Store below 30°C

The content is shown in English

Product introduction

Biratrone 500 Tablet is given as an injection under the supervision of a doctor, do not self administer the injection. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Biratrone Tablet

Prostate cancer

Benefits of Biratrone Tablet

Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Biratrone 500 Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Biratrone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Biratrone

Vomiting
Decreased potassium level in blood
Fatigue
Diarrhea
High blood pressure
Cough
Breathlessness
Joint pain
Flushing (sense of warmth in the face, ears, neck and trunk)
Constipation
Peripheral edema
Indigestion
Upper respiratory tract infection
Nasopharyngitis (inflammation of the throat and nasal passages)
Bruise
Insomnia (difficulty in sleeping)
Blood in urine
Hematoma

How to use Biratrone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Biratrone 500 Tablet is to be taken on an empty stomach.

How Biratrone Tablet works

Biratrone 500 Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

All substitutes for Biratrone 500 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Biratrone 500 Tablet treats prostate cancer that has spread to other parts of the body.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Biratrone 500 Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Biratrone 500 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Biratrone 500 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Biratrone 500 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Biratrone 500 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Because of the limited information, cautious use of Biratrone 500 Tablet is recommended in patients with severe kidney disease.

Liver

CAUTION

Biratrone 500 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Can Biratrone 500 Tablet cure prostate cancer?

Biratrone 500 Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Biratrone 500 Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Biratrone 500 Tablet.

Is Biratrone 500 Tablet a chemotherapy drug?

Biratrone 500 Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Biratrone 500 Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.

Why do I need to take prednisolone with Biratrone 500 Tablet?

Your doctor will always prescribe prednisolone with Biratrone 500 Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Biratrone 500 Tablet.

Does Biratrone 500 Tablet affect liver?

Biratrone 500 Tablet can cause severe liver problems. In very rare cases, Biratrone 500 Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Biratrone 500 Tablet.

Fact Box

Chemical Class

Androgen derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
Chemocare. Abiraterone Acetate. [Accessed 03 Jul. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medizia Biotech
Address: Near Matka Chowk, Ambala Road, Jagadhri, Distt. Yamuna Nagar-135003 (Haryana)

Vendor Details

Country of origin: India

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Biratrone 500 Tablet

Biratrone 500 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Biratrone Tablet

Benefits of Biratrone Tablet

Side effects of Biratrone Tablet

How to use Biratrone Tablet

How Biratrone Tablet works

All substitutes for Biratrone 500 Tablet

ZABpro 500mg Tablet

Zelgor 500mg Tablet

Abiratred 500mg Tablet

Bdron 500 Tablet

ABUra 500 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can Biratrone 500 Tablet cure prostate cancer?

Is Biratrone 500 Tablet a chemotherapy drug?

Why do I need to take prednisolone with Biratrone 500 Tablet?

Does Biratrone 500 Tablet affect liver?

How frequently should the liver investigations be done?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests