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Benoquin Ointment

Monobenzone (20% w/w)
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Benoquin Ointment is used for depigmentation. It is used to permanently lighten the skin in people with extensive vitiligo. It works by increasing the elimination of melanin from skin cells.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹316 MRP ₹35010% off 
 
 
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General Information

The content is shown in English
Benoquin Ointment image
Benoquin Ointment image

Product introduction

Benoquin Ointment is for external use only. You should always use it exactly as your doctor has told you. You must wash your hands thoroughly before and after applying this medicine. This medicine should be used regularly to get the most benefit from it. Do not use more than you need as some side effects may be increased.

Benoquin Ointment has a few potential side effects but not everyone will get them. These may include application site reactions like burning, irritation, itching, and redness. Serious allergic reaction to this drug is rare but let your doctor know if you’re bothered by side effects or they do not go away. Make sure you read the instructions that come with your medicine. Avoid contact with eyes. In case of accidental contact, you should rinse your eyes thoroughly with water.

You can start applying Benoquin Ointment to a small portion of unbroken skin or near the pigmented area for a period of several days for checking allergic reaction. You should discontinue it if itching, excessive inflammation, or swelling occurs. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. If no improvement is seen after two months of treatment, the use of this product should be discontinued.

Uses of Benoquin Ointment

Benefits of Benoquin Ointment

Vitiligo
Vitiligo is a condition in which the skin loses its natural color in patches. Benoquin Ointment effectively blocks that process in the skin that leads to discoloration. It also reduces any redness, rash, pain or itchiness that may be caused in this condition. This improves your self-esteem and confidence as your appearance changes. You should always use it as prescribed to get the full benefits.

Side effects of Benoquin Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Benoquin
  • Application site reactions (burning, irritation, itching and redness)

How to use Benoquin Ointment

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

How Benoquin Ointment works

Benoquin Ointment is a depigmenting agent. It works by increasing the elimination of melanin (skin darkening pigment) from skin cells. This helps lighten the skin in vitiligo.

Quick tips

  • Benoquin Ointment helps lighten the skin in people with vitiligo.
  • It may take up to 4 months to complete treatment. Keep using the medication as prescribed.
  • Apply it in a thin layer to the pigmented areas of skin and rub in gently.
  • It can make your skin more sensitive to sun. Use sunscreen and protective clothing when outdoors. 
  • It may also cause changes in the color of your untreated skin. Talk to your doctor if this bothers you.
  • Inform your doctor if your condition does not improve after 1 month of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Benoquin Ointment during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Benoquin Ointment during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Benoquin Ointment is used only for permanent depigmentation of the skin in patients with widespread vitiligo that covers more than half of the body. It is not a cosmetic skin lightener and should never be used for freckles, melasma, or tanning spots.
No. Benoquin Ointment is a strong depigmenting medicine, not a mild cosmetic bleach. Using it for skin lightening in people without vitiligo can cause permanent, uneven loss of skin color.
Individuals should not use Benoquin Ointment if they are allergic to monobenzone or any of its ingredients, or if they want it only for cosmetic lightening. It is strictly for patients with extensive vitiligo.
Yes. Benoquin Ointment often causes irreversible depigmentation. Once the pigment is lost, your skin may remain permanently white and extra sensitive to sunlight.
You should stop using Benoquin Ointment and call your doctor if you develop severe irritation, burning, rashes, or eczema-like skin reactions. In some cases, areas far away from where the medicine was applied may also lose pigment permanently.
Yes. Once your skin is depigmented with Benoquin Ointment, it will remain highly sensitive to sunlight for the rest of your life. You must use sunscreen regularly and protect your skin whenever you are outdoors.
The safety of Benoquin Ointment has not been established in children under 12 years, so it should not be used in younger patients.
Yes. Even areas of normal skin far from the Benoquin Ointment application site may become depigmented. The loss of color may be irregular, excessive, unsightly, and it is often permanent.
The exact time Benoquin Ointment takes to work is not known. However, depigmentation usually occurs within one to four months of treatment. If there is no improvement after four months, your doctor may stop the treatment.

Fact Box

Chemical Class

4- alkoxyphenols

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Anti Pigmentation & Skin Lightening Agents

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1055.
  2. Monobenzone. Costa Mesa, CA: ICN Pharmaceuticals, Inc.; [Accessed 03 Apr. 2019] (online) Available from:
  3. PubChem. Monobenzone. [Accessed 03 Apr. 2019] (online) Available from:
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User feedback

Once A Day
71%
Twice A Day
18%
Thrice A Day
12%
Vitiligo
80%
Others
20%
Excellent
38%
Poor
36%
Average
26%
No Side Effect
85%
Application site reactions (burning, irritation, itching and redness)
15%
With or without food
70%
Empty stomach
20%
With food
10%
Not Expensive
48%
Average
45%
Expensive
6%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mac Laboratories Ltd
Address: KIROLVIDYAVIHAR (WEST) MUMBAI MH 400086 INDIA

Vendor Details

Country of origin: India
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