
Bavencio Injection
Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 23 Mar 2026 | 11:29 AM (IST)
Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.
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General Information
The content is shown in English



Product introduction
Bavencio Injection is given as an injection by a healthcare professional. For it to be effective, complete the course of the medicine and do not discontinue even if you get better until the course is completed.
Some common side effects of this medicine include fatigue, nausea, diarrhea, decreased appetite, and muscle pain amongst others. These are usually mild and go away with time. However, if they persist or get worse, let the doctor know.
Before receiving the medicine, you should let your doctor if you have ever had an allergic reaction to any medicine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this medicine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this medicine.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Some common side effects of this medicine include fatigue, nausea, diarrhea, decreased appetite, and muscle pain amongst others. These are usually mild and go away with time. However, if they persist or get worse, let the doctor know.
Before receiving the medicine, you should let your doctor if you have ever had an allergic reaction to any medicine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this medicine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this medicine.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Uses of Bavencio Injection
Benefits of Bavencio Injection
Treatment of Urinary bladder cancer
Bavencio Injection helps to treat urinary bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse and should not be self-administered.
Bavencio Injection helps to treat urinary bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse and should not be self-administered.
Side effects of Bavencio Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bavencio
- Fatigue
- Musculoskeletal (bone, muscle or joint) pain
- Diarrhea
- Nausea
- Infusion site reaction
- Rash
- Decreased appetite
- Peripheral edema
- Urinary tract infection
- High blood pressure
- Mucositis
- Hand-foot syndrome
- Voice change
- Decreased level of thyroid hormones
- Liver toxicity
- Coughing up blood
- Breathlessness
- Abdominal pain
- Headache
How to use Bavencio Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Bavencio Injection works
Bavencio Injection is a type of immunotherapy. It activates the body's immune system to fight cancer cells. Avelumab targets and blocks a protein (PD-L1) found on the surface of certain immune cells. Blocking PD-L1 activates the immune cells to find and kill cancer cells.
Quick tips
- Do not receive any immunization or vaccination without your doctor’s approval while taking Bavencio Injection.
- You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your health care provider.
- Inform your doctor immediately if you notice signs or symptoms of skin rash, itchy skin, a rash with tiny spots and bumps, reddening of the skin.
- To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
- Use contraceptives, and do not conceive a child (get pregnant) while taking Bavencio Injection. Barrier methods of contraception, such as condoms, are recommended.
- Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
- Do not drive or use machines after you have received Bavencio Injection since you might feel tired or dizzy.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bavencio Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Bavencio Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
UNSAFE
Bavencio Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
CONSULT YOUR DOCTOR
It is not known whether Bavencio Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Bavencio Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver
SAFE IF PRESCRIBED
Bavencio Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Interaction with drugs
Taking Bavencio with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)
Conomitant use should be avoided.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Other Anticancer Agents
References
- Bavencio (Avelumab) [Product Information]; 2021. [Accessed 16 Nov. 2022] (online) Available from:
- Avelumab [Prescribing Information]. Rockland, MA: : EMD Serono, Inc.; 2022. [Accessed 16 Nov. 2022] (online) Available from:
- Avelumab [Summary of Product Characteristics]. Modugno, Italy: Merck Serono S.p.A.; 2020. [Accessed 16 Nov. 2022] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Merck Ltd
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India
Vendor Details
Country of origin: Swaziland
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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