Avastin 400mg Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.

Avastin 400mg Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Avastin 400mg Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.

The most common side effects of this medicine include nosebleeds, headache, high blood pressure, rhinitis, protein in urine, change in taste, dry skin, bleeding, lacrimation disorder, back pain, and exfoliative dermatitis. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug can lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Avastin Injection

Side effects of Avastin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Avastin

Nosebleeds
Headache
High blood pressure
Inflammation of the nose
Protein in urine
Taste change
Dry skin
Hemorrhage
Increased lacrimation
Back pain
Exfoliative dermatitis

How to use Avastin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Avastin Injection works

Avastin 400mg Injection is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Avastin 400mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Avastin 400mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Avastin 400mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Avastin 400mg Injection may cause side effects which could affect your ability to drive.
Sleepiness and fainting have been reported with Avastin 400mg Injection and this may impair your ability to drive.

Kidney

SAFE IF PRESCRIBED

Avastin 400mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avastin 400mg Injection may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Avastin 400mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Avastin 400mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Avastin Injection?

If you miss a dose of Avastin 400mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Avastin 400mg Injection

₹101275/Injection

Krabeva 400mg Injection

Biocon

₹43212/injection

65% cheaper

Bevacirel 400mg Injection

Reliance Life Sciences

₹38856.34/injection

69% cheaper

Avastimab 400mg Injection

RPG Life Sciences Ltd

₹52500/injection

57% cheaper

Avangio Injection

PlasmaGen Biosciences Pvt Ltd

₹36900/injection

70% cheaper

Bevnexxa 400mg Injection

Celon Laboratories Ltd

₹39000/injection

68% cheaper

View all substitutes

Quick tips

Avastin 400mg Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
Avastin 400mg Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Avastin 400mg Injection.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Vascular Endothelial Growth Factor (VEGF) Inhibitors

Interaction with drugs

Taking Avastin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Panitumumab (Injection Route) Severe

Do not consume Panitumumab with Bevacizumab during the treatment of metastatic colon cancer. Concomitant use may cause lethal infections.

Diclofenac (Oral Route) Moderate

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

Diclofenac (Injection Route) Moderate

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

Imatinib mesylate (Oral Route) Moderate

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

Ticagrelor (Oral Route) Moderate

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

View all drug interactions

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

Smears show metastatic mucinous adenocarcinoma.HISTOPATHOLOGY REPORT.sir is there any treatment Sir my mom firstly suffered from stomach pain.Then say about doing ultra sound test which is as:Neoplasm Stomach Pylrus.Fresh blood in corpus .polypoid growth in pylrus biopy taken from HPE Sir please help doctors already said there is no treatment for this stomach cancer disease

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Cancer is treated based on stage of cancerPlease upload reports of Ultrasound and endoscopy

User feedback

What are you using Avastin Injection for?

Cancer of col*

33%

Ovarian cance*

29%

Others

24%

Brain tumor

10%

Non-small cel*

*Cancer of colon and rectum, Ovarian cancer, Non-small cell lung cancer

How much was the improvement?

Average

56%

Poor

22%

Excellent

22%

What were the side-effects while using Avastin 400mg Injection?

Rectal bleedi*

17%

Headache

17%

Peripheral ne*

17%

Tasteless

17%

Loss of appet*

17%

*Rectal bleeding, Peripheral neuropathy (tingling and numbness of feet and hand), Loss of appetite

How do you take Avastin Injection?

With food

100%

Please rate Avastin 400mg Injection on price

Expensive

100%

FAQs

What kinds of cancer can Avastin 400mg Injection be used for ?

Avastin 400mg Injection is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).

How is Avastin 400mg Injection given?

Avastin 400mg Injection is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.

How long can I take Avastin 400mg Injection for?

You keep taking Avastin 400mg Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Avastin 400mg Injection. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.

How Avastin 400mg Injection works differently from chemotherapy?

Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Avastin 400mg Injection is to prevent the growth of new blood vessels that feed tumors. This causes the tumour to shrink, or to stop growing.

Does a person taking Avastin 400mg Injection still need chemotherapy?

Chemotherapy is still needed along with taking Avastin 400mg Injection. It makes chemotherapy work better.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Avastin (Bevacizumab) [Product Information]. [Accessed 07 Oct. 2024] (online) Available from:
Avastin (Bevacizumab) [Prescribing Information]. South San Francisco, CA: Genentech, Inc.; 2022. [Accessed 07 Oct. 2024] (online) Available from:
Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1739-40.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 142-43.
Bevacizumab. South San Francisco, California: Genentech, Inc.; 2004 [revised Sep. 2011]. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bevacizumab. [Updated 2019 Jul 20]. [Accessed 18 Feb. 2020] (online) Available from:

Marketer details

Name: Roche Products India Pvt Ltd

Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Country of origin: India
Expires on or after: August, 2025

A licensed vendor partner from your nearest location will deliver Avastin 400mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India