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03 Apr 2020 | 10:18 AM (IST)
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Arzerra Injection

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Arzerra Injection is used in the treatment of blood cancer (chronic lymphocytic leukemia). It binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.

Arzerra Injection is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include injection site reaction, nausea, diarrhea, and upper respiratory tract infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and kidney function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Side effects of Arzerra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arzerra

  • Nausea
  • Diarrhea
  • Breathlessness
  • Cough
  • Flushing of skin
  • Low energy
  • Skin rash

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Breathlessness
    Control your breaths by breathing in slowly through your nose and breathing out through your mouth. Sitting on a chair and leaning your chest slightly forward may also help. Increase the flow of air around you by opening windows or using a fan. Try to learn breathing techniques and do regular physical exercise. Wearing loose clothing around your waist and chest may also be helpful. Your breathing will usually return to normal within a few weeks of starting the medicine. Tell your doctor if your symptoms do not improve or get worse. Shortness of breath can also be a sign of an ongoing or worsening heart problem.
  • Coping with Cough
    Get plenty of rest as exhausting or stressing out yourself could aggravate your condition. You should drink plenty of fluids as it will keep your throat moist and comfortable. Try taking steam inhalation. The moisture can ease your breathing and loosen mucus. You can consider sipping warm water or tea with honey and lemon. This will keep your nose and throat from being too dry. Using an air humidifier may also help. You can also gargle with salt water several times a day. See your doctor if your symptoms last longer than 3 weeks or get worse quickly. Avoid alcohol and do not smoke as they can aggravate your conditions.
  • Coping with Flushing of skin
    Sip cold or iced drinks. Try cutting down on coffee, tea and alcohol. It might help to keep the room cool and use a fan. You could also spray cool water on your face. Wear layers of light clothing that you can easily take off if you overheat. Breathe deeply and try to relax. Have a lukewarm shower or bath instead of a hot one. Avoid smoking and cut down on alcohol. The flushing should go away after a few days. If it does not go away or causes problems, contact your doctor. There may be medicines that can help.
  • Coping with Skin rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.

How to use Arzerra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Arzerra Injection works

Arzerra Injection is a monoclonal antibody. It specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Arzerra Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Arzerra Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Arzerra Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Arzerra Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Arzerra Injection is safe to use in patients with kidney disease. No dose adjustment of Arzerra Injection is recommended.
Liver
UNSAFE
Arzerra Injection is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Arzerra Injection is given as an IV infusion under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count (CBC), liver and kidney function.
  • Inform your doctor if you experience fever, chills, rash, dizziness and shortness of breath during the treatment.

Fact Box

Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No

Patient Concerns

arrow
She is suffering from chronic myeloid leukemia
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1747-48.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1011.
  3. Ofatumumab. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Jan. 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Dr. Annie Besant Road, Mumbai - 400 030
A licensed vendor partner from your nearest location will deliver Arzerra Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP50556  Get 10% OFF
Best Price
₹45556
3 injections in 1 vial
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