Alprax Plus Tablet SR

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 09 Feb 2026 | 03:40 PM (IST)

Alprax Plus Tablet SR is a prescription medicine used to treat depression. It is a combination medicine which calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also increases the levels of some chemical messengers in the brain and improves mood.

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General Information

Contains

Alprazolam (0.5mg)+ Sertraline (25mg)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Alprax Plus Tablet SR is taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain consistent levels of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as this may cause nausea, stomach upset, flu-like withdrawal symptoms, sleep disturbance and anxiety.

Some common side effects of this medicine include nausea, vomiting, diarrhea, confusion, memory impairment, and low sexual desire. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food and exercise regularly. On the other hand, weight loss can be managed by consulting a dietitian who can help you increase the food portions. It is important to inform your doctor if you develop any unusual changes in mood as it may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Alprax Plus Tablet SR

Depression

Benefits of Alprax Plus Tablet SR

Depression
Alprax Plus Tablet SR works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Alprax Plus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alprax Plus

Nausea
Vomiting
Diarrhea
Confusion
Memory impairment
Uncoordinated body movements
Drowsiness
Tiredness
Delayed ejaculation
Anorgasmia (decreased orgasm)
Low sexual desire

How to use Alprax Plus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alprax Plus Tablet SR may be taken with or without food.

How Alprax Plus Tablet SR works

Alprax Plus Tablet SR is a combination of two medicines:

Quick tips

Alprax Plus Tablet SR is prescribed for the treatment of depression.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
Do not stop taking Alprax Plus Tablet SR unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Avoid the use of Alprax Plus Tablet SR along with certain medications like aspirin, warfarin, ibuprofen, or naproxen as it might increase the risk of bleeding.
Inform your doctor if you observe changes in appetite or weight.
Inform your doctor if you are taking any other antidepressant.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Alprax Plus Tablet SR may affect the levels of sugar in your blood.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Alprax Plus Tablet SR may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Alprax Plus Tablet SR is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Alprax Plus Tablet SR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Alprax Plus Tablet SR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Alprax Plus Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Alprax Plus Tablet SR is unsafe to use in patients with liver disease and should be avoided.
Use of Alprax Plus Tablet SR is not recommended in patients with severe liver disease.

Frequently asked questions

Can I stop taking Alprax Plus Tablet SR if I feel well?

No, you should continue to take Alprax Plus Tablet SR even if you feel well. If you stop taking Alprax Plus Tablet SR suddenly, serious withdrawal problems may occur. Consult your doctor instead of stopping it yourself, your doctor might decrease your dose gradually.

Can the use of Alprax Plus Tablet SR cause sleepiness?

Yes, Alprax Plus Tablet SR can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

What are the instructions for the storage and disposal of Alprax Plus Tablet SR?

Keep this medicine in the container or pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

User feedback

Patients taking Alprax Plus Tablet SR

Once A Day

95%

Twice A Day

Alternate Day

What are you using Alprax Plus Tablet SR for?

Depression

78%

Others

22%

How much was the improvement?

Excellent

67%

Poor

17%

Average

17%

What were the side-effects while using Alprax Plus Tablet SR?

No Side Effect

100%

How do you take Alprax Plus Tablet SR?

With food

100%

Please rate Alprax Plus Tablet SR on price

Not Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Alprax Plus Tablet SR

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Alprax Plus Tablet SR

Benefits of Alprax Plus Tablet SR

Side effects of Alprax Plus Tablet SR

How to use Alprax Plus Tablet SR

How Alprax Plus Tablet SR works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can I stop taking Alprax Plus Tablet SR if I feel well?

Can the use of Alprax Plus Tablet SR cause sleepiness?

What are the instructions for the storage and disposal of Alprax Plus Tablet SR?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Alprax Plus Tablet SR

What are you using Alprax Plus Tablet SR for?

How much was the improvement?

What were the side-effects while using Alprax Plus Tablet SR?

How do you take Alprax Plus Tablet SR?

Please rate Alprax Plus Tablet SR on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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