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Agidol Plus 5mg Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 19 Jun 2026 | 05:57 PM (IST)
₹35.4 MRP ₹39.3810% off 
As per Ministry of Health and Family Welfare
 
 
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Agidol Plus 5mg Tablet image
Agidol Plus 5mg Tablet image

Product introduction

Agidol Plus 5mg Tablet also helps by improving muscle control and reducing the stiffness of the muscle. It may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Agidol Plus Tablet

Benefits of Agidol Plus Tablet

Schizophrenia
Schizophrenia is a long-term mental health condition that affects how a person thinks, feels, and behaves. It can cause symptoms like hallucinations (seeing or hearing things that aren't there), delusions, and severe mood or behavior changes. Agidol Plus 5mg Tablet helps manage the core symptoms of schizophrenia by balancing brain chemicals involved in mood and thinking, and reduces movement-related side effects often caused by antipsychotic treatment. This medicine helps improve daily functioning, thinking clarity, and emotional stability in individuals living with schizophrenia.

Side effects of Agidol Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Agidol Plus
  • Nausea
  • Constipation
  • Dryness in mouth
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Increased prolactin level in blood
  • Dizziness
  • Blurred vision
  • Nervousness

How to use Agidol Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agidol Plus 5mg Tablet may be taken with or without food.

How Agidol Plus Tablet works

Agidol Plus 5mg Tablet is a combination of two medicines: Haloperidol and Trihexyphenidyl. Haloperidol is a typical antipsychotic. It works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is added to treat and prevent these side effects.

Quick tips

  • Agidol Plus 5mg Tablet is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug induced abnormal movements.
  • Be cautious while driving or doing anything that requires concentration as Agidol Plus 5mg Tablet can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication as it may lower its efficacy.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Agidol Plus 5mg Tablet without talking to your doctor first as it may cause worsening of symptoms.
  • Agidol Plus 5mg Tablet is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug induced abnormal movements.
  • Be cautious while driving or doing anything that requires concentration as Agidol Plus 5mg Tablet can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication as it may lower its efficacy.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Agidol Plus 5mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Agidol Plus 5mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Agidol Plus 5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Agidol Plus 5mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
If Agidol Plus 5mg Tablet is used, monitor the baby for excessive sleepiness.
Driving

Driving

UNSAFE
Agidol Plus 5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Agidol Plus 5mg Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney

Kidney

CAUTION
Agidol Plus 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver

Liver

CAUTION
Agidol Plus 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
All

Frequently asked questions

Agidol Plus 5mg Tablet is used to treat schizophrenia and other conditions in which a person may experience disturbed thoughts, unusual behaviour, hallucinations, or difficulty distinguishing between what is real and what is not. It helps improve thinking, behaviour, and emotional stability, making it easier to carry out daily activities.
Agidol Plus 5mg Tablet contains Haloperidol and Trihexyphenidyl. Haloperidol helps control symptoms such as hallucinations, delusions, agitation, and disturbed thinking by acting on certain chemical messengers in the brain. Trihexyphenidyl helps reduce movement-related side effects such as muscle stiffness, shaking, and involuntary movements that can occur with antipsychotic treatment. Together, these medicines help improve symptom control while reducing treatment-related discomfort.
Yes, Agidol Plus 5mg Tablet can generally be taken with or without food. Taking it the same way each day may help you remember your dose and maintain consistent treatment. Follow your doctor's instructions regarding how to take the medicine.
Agidol Plus 5mg Tablet is usually prescribed for long-term management of schizophrenia and related conditions. Continue taking it for as long as advised by your doctor, even if you start feeling better. Stopping treatment too early may cause symptoms to return or worsen.
Some individuals may experience dry mouth, constipation, blurred vision, dizziness, drowsiness, restlessness, or difficulty concentrating while taking Agidol Plus 5mg Tablet. These side effects are often mild and may improve as the body adjusts to treatment. Rarely, serious side effects can occur, including involuntary movements of the face, tongue, or body (tardive dyskinesia), which may be irreversible. Contact your doctor if you notice unusual muscle movements, severe stiffness, high fever, confusion, or other concerning symptoms.
Seek immediate medical attention if you develop severe muscle stiffness, high fever, confusion, difficulty swallowing, uncontrolled body movements, seizures, a fast or irregular heartbeat, or severe allergic reactions such as swelling of the face, lips, tongue, or throat.
Haloperidol helps manage the symptoms of schizophrenia, while Trihexyphenidyl helps reduce movement-related side effects that can occur during treatment with antipsychotic medicines. Combining both ingredients may improve overall treatment comfort and adherence.
The Trihexyphenidyl in Agidol Plus 5mg Tablet helps reduce symptoms such as muscle stiffness, tremors, and involuntary movements that may occur as a result of treatment with Haloperidol. This may help make daily activities more comfortable.
Do not stop taking Agidol Plus 5mg Tablet without speaking to your doctor. Suddenly stopping treatment may cause symptoms to return, worsen, or become more difficult to control. Your doctor will advise if the medicine needs to be reduced or discontinued.
Some individuals may notice changes in appetite or weight while taking medicines used for mental health conditions. Maintaining a balanced diet, staying physically active, and monitoring your weight regularly may help. If you notice significant weight changes, discuss them with your doctor.
Trihexyphenidyl may worsen certain conditions such as glaucoma or difficulty passing urine in some individuals. Informing your doctor about these conditions helps ensure that the treatment remains safe and appropriate for you.
Schizophrenia symptoms often require ongoing treatment to remain well controlled. Taking Agidol Plus 5mg Tablet regularly as prescribed helps maintain stable symptom control and may reduce the likelihood of symptom recurrence.
Some symptoms such as agitation or restlessness may improve earlier, while improvements in thinking, behaviour, and other symptoms may take several weeks. Continue taking the medicine as prescribed and attend regular follow-up visits with your doctor.
If your symptoms continue, worsen, or new symptoms develop despite taking Agidol Plus 5mg Tablet regularly, inform your doctor. Your doctor may review your treatment plan and determine whether any adjustments are needed.

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User feedback

Twice A Day
38%
Once A Day
38%
Thrice A Day
25%
Schizophrenia
100%
Excellent
67%
Average
33%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Name: AGM Biotec
Address: E-49, RUDRAPUR - 263153, Opposite Dharamshala

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Country of origin: India
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